scholarly journals Lectins as probes of chromatin structure. Binding of concanavalin A to purified rat liver chromatin.

1977 ◽  
Vol 252 (20) ◽  
pp. 7062-7067
Author(s):  
W B Rizzo ◽  
M Bustin
Keyword(s):  
Rat Liver ◽  
Concanavalin A ◽  
Chromatin Structure ◽  
Liver Chromatin

Early alterations in rat liver chromatin structure after a single dose of diethylnitrosamine

1983 ◽  
Vol 3 (2) ◽  
pp. 185-188
Author(s):  
Karl Letnansky ◽  
Hratschik R. Vardapetjan
Keyword(s):  
Single Dose ◽  
Rat Liver ◽  
Chromatin Structure ◽  
Chemical Modifications ◽  
Lower Melting ◽  
Melting Temperatures ◽  
Liver Chromatin ◽  
Rat Livers ◽  
Rapid Shift ◽  
Good Agreement

In the chromatin of 24-h regenerating rat livers, derivative melting profiles are characterized by a high proportion of transitions above 90°C. After the injection of diethylnitrosamine there is a rapid shift to lower melting temperatures. This is due to a rearrangement of the chromatin to higher amounts of nucleosomal components but possibly also a consequence of chemical modifications and conformational alterations of the DNA. In the nonregenerating liver essentially the same observations can be made, although reactions proceed significantly slower. These results are in good agreement with the observation that carcinogens are more active in tissues stimulated to rapid proliferation as compared to resting tissues.

Structure of Chromatin DNA not Complexed with Protein

1974 ◽  
Vol 29 (9-10) ◽  
pp. 597-601 ◽  
Author(s):  
K. Hartmut Richter ◽  
Constantin E. Sekeris
Keyword(s):  
Rat Liver ◽  
Chromatin Structure ◽  
Dnase I ◽  
Hydroxy Apatite ◽  
Free Dna ◽  
Liver Chromatin ◽  
Total Dna ◽  
The Mean ◽  
Phosphate Groups

Abstract Rat liver chromatin was titrated by poly-ᴅ-lysine of mol.wt. 140,000. Approximately 32% of the phosphate groups of the chromatin were found to react with the polycation. By submitting the chromatin-poly-ᴅ-lysine complex to pronase and DNase I digestion and by further submitting the obtained DNA-lysine complex to hydroxy-apatite-chromatography, "free" DNA was isolated. The mean S-value of this DNA was found to be 10 ± 0 .8 , corresponding to approximately 2100 nucleo­ tide pairs, its renaturation kinetics similar to total DNA. On the basis of these results and on the findings that histone-saturated DNA-histone recombinates are digested with DNase I up to 65% a model of chromatin structure was proposed, taking into account protein covered-and free DNA regions

scholarly journals Studies on the Binding of Concanavalin A to Rat Liver Mitochondria

1973 ◽  
Vol 248 (9) ◽  
pp. 3137-3145 ◽  
Author(s):  
Robert H. Glew ◽  
Samuel C. Kayman ◽  
Mark S. Kuhlenschmidt
Keyword(s):  
Rat Liver ◽  
Concanavalin A ◽  
Liver Mitochondria ◽  
Rat Liver Mitochondria

Purification and properties of a neutral protease from rat liver chromatin

Biochemistry ◽  
1974 ◽  
Vol 13 (25) ◽  
pp. 5128-5134 ◽  
Author(s):  
Ming Ta Chong ◽  
William T. Garrard ◽  
James Bonner
Keyword(s):  
Rat Liver ◽  
Neutral Protease ◽  
Purification And Properties ◽  
Liver Chromatin

Association of the thyroid hormone receptor with rat liver chromatin

Biochemistry ◽  
1981 ◽  
Vol 20 (24) ◽  
pp. 6781-6789 ◽  
Author(s):  
Donald B. Jump ◽  
Steven Seelig ◽  
Harold L. Schwartz ◽  
Jack H. Oppenheimer
Keyword(s):  
Thyroid Hormone ◽  
Rat Liver ◽  
Hormone Receptor ◽  
Thyroid Hormone Receptor ◽  
Liver Chromatin
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