Use of an 18-mm I.D. column for analytical- and semi-preparative-scale high-pressure liquid chromatography

1976 ◽  
Vol 122 ◽  
pp. 317-329 ◽  
Author(s):  
E. Godbille ◽  
P. Devaux
Keyword(s):  
High Pressure ◽  
Liquid Chromatography ◽  
High Pressure Liquid Chromatography ◽  
Preparative Scale

scholarly journals Diastereomers of the insect repellent 3-acetyl-2-(2′,6′-dimethyl-5′-heptenyl)oxazolidine. Isolation by high pressure liquid chromatography and characterization by 13C nuclear magnetic resonance spectroscopy

1984 ◽  
Vol 62 (1) ◽  
pp. 96-100 ◽  
Author(s):  
Wesley G. Taylor ◽  
Tom T. Nakashima
Keyword(s):  
Nuclear Magnetic Resonance ◽  
High Pressure ◽  
Liquid Chromatography ◽  
Magnetic Resonance ◽  
High Pressure Liquid Chromatography ◽  
Resonance Spectroscopy ◽  
Insect Repellent ◽  
Preparative Scale ◽  
13C Nuclear Magnetic Resonance ◽  
Nuclear Magnetic

Preparative-scale high pressure liquid chromatography on 3-acetyl-2-(2′,6′-dimethyl-5′-heptenyl)oxazolidine (1), a complex acetamide derivative of citronellal, resulted in isolation of the diastereomeric forms of this insect repellent. The two diastereomers were designated as 1a and 1b on the basis of their order of elution from silica gel and from a variety of capillary gas chromatography columns. Interpretation of the 13C nuclear magnetic resonance spectra of 1a and 1b was accomplished by comparison with model compounds and by off-resonance proton-decoupling experiments. Absolute stereochemical assignments were not made. Because of the amide group, the diastereomers existed in solution at ambient temperature as cis and trans rotational isomers, which caused nonequivalence of most of the carbon atoms, including the olefinic carbons at C-5′ and C-6′. trans Isomer (5) was concluded to be the major contributor to the rotational equilibrium. The spectrum of 3-acetyl-2-(4′-methyl-3′-pentenyl)oxazolidine (7) was also recorded for comparison.

Historical chemical annotations of Cinchona bark collections are comparable to results from current day high-pressure liquid chromatography technologies

2020 ◽  
Vol 249 ◽  
pp. 112375 ◽  
Author(s):  
Nataly Allasi Canales ◽  
Tobias Nikolaj Gress Hansen ◽  
Claus Cornett ◽  
Kim Walker ◽  
Felix Driver ◽  
...  
Keyword(s):  
High Pressure ◽  
Liquid Chromatography ◽  
High Pressure Liquid Chromatography
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