Homology relationship between the messenger RNA and heterogenous nuclear RNA of mouse L cells. A DNA excess hybridization study

1977 ◽  
Vol 109 (3) ◽  
pp. 437-453 ◽  
Author(s):  
B. David Hames ◽  
Robert P. Perry
1977 ◽  
Vol 115 (4) ◽  
pp. 695-714 ◽  
Author(s):  
Ueli Schibler ◽  
Dawn E. Kelley ◽  
Robert P. Perry
Keyword(s):  
L Cells ◽  

1979 ◽  
Vol 135 (4) ◽  
pp. 879-891 ◽  
Author(s):  
Maureen Gilmore-Hebert ◽  
Randolph Wall

1981 ◽  
Vol 1 (2) ◽  
pp. 179-187 ◽  
Author(s):  
M Salditt-Georgieff ◽  
M M Harpold ◽  
M C Wilson ◽  
J E Darnell

The rate of synthesis in Chinese hamster cells of 5' cap structures, m7 GpppNmp, in large (greater than 700 bases) heterogeneous nuclear ribonucleic acid (RNA) molecules is two to three times faster than the synthesis of 3'-terminal polyadenylic acid segments. As judged by presence of caps, newly synthesized polysomal messenger RNA, exclusive of messenger RNA the size of histone messenger RNA, is more than 90% in the polyadenylated category. It appears, therefore, that between half and two-thirds of the long capped heterogeneous nuclear RNA molecules do not contribute a capped polysomal derivative to the cytoplasm. There are capped, nonpolysomal, non-polyadenylated molecules with a rapid turnover rate that fractionate with the cytoplasm. These metabolically unstable molecules either could represent leakage into the cytoplasm during fractionation or could truly spend a brief time in the cytoplasm before decay.


1994 ◽  
Vol 57 (5) ◽  
pp. 760-764 ◽  
Author(s):  
Mitsuru Setoyama ◽  
Toshinobu Fujiyoshi ◽  
Shimako Mizoguchi ◽  
Yoshihiko Katahira ◽  
Shinji Yashiki ◽  
...  

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