Neonatal necrotizing enterocolitis in the absence of pneumatosis intestinalis

1983 ◽  
Vol 18 (3) ◽  
pp. 319
Author(s):  
J.J. Tepas
Keyword(s):  
Necrotizing Enterocolitis ◽  
Pneumatosis Intestinalis ◽  
Neonatal Necrotizing Enterocolitis

Neonatal Necrotizing Enterocolitis

1982 ◽  
Vol 29 (5) ◽  
pp. 1149-1170 ◽  
Author(s):  
Edwin G. Brown ◽  
Avron Y. Sweet
Keyword(s):  
Necrotizing Enterocolitis ◽  
Neonatal Necrotizing Enterocolitis

Intestinal Lesions Containing Coronavirus-like Particles in Neonatal Necrotizing Enterocolitis: An Ultrastructural Analysis

PEDIATRICS ◽  
1984 ◽  
Vol 73 (2) ◽  
pp. 218-224
Author(s):  
S. Rousset ◽  
O. Moscovici ◽  
P. Lebon ◽  
J. P. Barbet ◽  
P. Helardot ◽  
...  
Keyword(s):  
Electron Microscopy ◽  
Small Intestine ◽  
Necrotizing Enterocolitis ◽  
Intestinal Mucosa ◽  
Light And Electron Microscopy ◽  
Anaerobic Bacteria ◽  
Intestinal Lesions ◽  
Maternity Hospitals ◽  
Neonatal Necrotizing Enterocolitis

Since the outbreaks of neonatal necrotizing enterocolitis occurring in maternity hospitals of Paris and suburbs in 1979-1980, it has been possible to examine by light and electron microscopy gut specimens from ten newborns with this illness. Coronavirus-like particles, enclosed in intracytoplasmic vesicles of damaged epithelial cells of the intestinal mucosa, were observed in the small intestine, appendix, and colon. The ultrastructural study, supported by bacteriologic findings, suggests the role of coronavirus-like particles in the appearance of the lesions. Secondary proliferation of mainly anaerobic bacteria, probably responsible for pneumatosis, may aggravate the disease.

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