64: Intravesical Instillation of Epinephrine in Patients with Intractable Hemorrhagic Cystitis Due to Radiation Cystitis

2007 ◽  
Vol 177 (4S) ◽  
pp. 22-22
Author(s):  
Yung C. Chow ◽  
Jong M. Hsu ◽  
Wen C. Lin ◽  
Huang K. Chang ◽  
Yuh C. Yang ◽  
...  
Keyword(s):  
Hemorrhagic Cystitis ◽  
Intravesical Instillation ◽  
Radiation Cystitis

scholarly journals MP26-20 INTRAVESICAL INSTILLATION OF LIPOSOMAL-TACROLIMUS (LP-10) IS AN EFFECTIVE TREATMENT FOR CHRONIC RADIATION CYSTITIS

2016 ◽  
Vol 195 (4S) ◽  
Author(s):  
Bernadette Zwaans ◽  
Sarah Bartolone ◽  
Michael Chancellor ◽  
Peter Levanovich ◽  
Sarah Krueger ◽  
...  
Keyword(s):  
Effective Treatment ◽  
Intravesical Instillation ◽  
Radiation Cystitis ◽  
Chronic Radiation

scholarly journals Intravesical Instillation of Sodium Hyaluronate (Cystistat®) for the Treatment of Patients with Radiation Cystitis-Randomized Clinical Trial

2020 ◽  
Vol 13 (11) ◽  
Author(s):  
Farzad Allameh ◽  
Abbas Basiri ◽  
Saleh Ghiasy ◽  
Atefeh Javadi ◽  
Seyyed Ali Hojjati ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Clinical Trial ◽  
Hyaluronic Acid ◽  
Sodium Hyaluronate ◽  
Intravesical Instillation ◽  
Control Group ◽  
Radiation Cystitis ◽  
Vas Score ◽  
The Mean

Background: Radiotherapy (RT) is a choice to manage pelvic organ malignancies that can affect bladder; therefore, it causes radiation cystitis with some bothering urinary symptoms and decreasing the patient’s quality of life. Intravesical hyaluronic acid (HA) is an agent with promising results in some studies for cystitis, and Cystistat is a derivative of hyaluronic acid. Objectives: This clinical trial aimed at evaluating the effects of intravesical instillation of Cystistat on symptoms of radiation cystitis and quality of life (QOL). Methods: A total of 58 patients with radiation cystitis were randomized in 2 groups (case: 30, control: 28). One group received intravesical Cystistat, the other received normal saline weekly for up to 4 weeks and then monthly for up to 2 months. Hematuria, Visual Analog scale (VAS) and QOL based on King’s Health questionnaire were compared before and 3, 6 and 9 months after intravesical instillation. Results: The mean age of the patients was 63.93 ± 10.89 years old. The mean of each sub-category of QOL and total score of QOL, as well as, VAS score were significantly improved in comparison to the control group at each time of follow-ups (P < 0.05). Hematuria was significantly different in the 3rd, 6th and 9th month of follow-ups (P < 0.05). Conclusions: Findings showed that patients with radiation cystitis could significantly benefit from intravesical instillation of HA, their hematuria would be successfully resolved rather than control group in addition to lowering the VAS score, so their QOL would be improved.

Use of Prostaglandin F2 Alpha for Cyclophosphamide-Induced Hemorrhagic Cystitis

1994 ◽  
Vol 10 (5) ◽  
pp. 204-206 ◽  
Author(s):  
Christina L. Cocnata
Keyword(s):  
English Language ◽  
Case Reports ◽  
Data Extraction ◽  
Hemorrhagic Cystitis ◽  
Intravesical Instillation ◽  
Optimal Dosage ◽  
Bladder Irrigation ◽  
Optimal Dosage Regimen ◽  
Study Selection ◽  
Prostaglandin F

Objective: To examine the use of prostaglandin F2 alpha in treating cyclophosphamide-induced hemorrhagic cystitis. Data Sources: An English language literature search using MEDLINE 1982–1993 and bibliographic reviews of related textbooks and review articles. Study Selection: Articles containing pertinent information regarding the therapeutic use and effects of prostaglandin F2 alpha as a treatment for cyclophosphamide-induced hemorrhagic cystitis in humans. Data Extraction: Resources were evaluated and information was extracted independently. Data Synthesis: A review of human cases suggests that intravesical administration of prostaglandin F2 alpha may be an effective bedside therapy for cyclophosphamide-induced hemorrhagic cystitis. Adverse reactions are limited primarily to local effects. The optimal dosage regimen of intravesical prostaglandin F2 alpha is not clearly established. Conclusions: Patients with intractable vesical hemorrhage secondary to cyclophosphamide administration may benefit from bedside intravesical instillation of prostaglandin F2 alpha. Information in the literature regarding prostaglandin bladder irrigation is scarce, and confined to case reports. Clinical studies are needed to endorse and/or refute the efficacy of intravesical instillation of prostaglandin F2 alpha as a treatment modality for hemorrhagic cystitis.

scholarly journals Radiation Induced Hemorrhagic Cystitis: Current Treatments

2017 ◽  
Vol 35 (4) ◽  
pp. 391
Author(s):  
Chaiyut Kongseang ◽  
Worapat Attawettayanon ◽  
Watid Kanchanawanichkul
Keyword(s):  
Mortality Rate ◽  
Hemorrhagic Cystitis ◽  
Moderate Degree ◽  
Gross Hematuria ◽  
Current Management ◽  
Correct Treatment ◽  
Radiation Cystitis ◽  
Common Presentation ◽  
Genitourinary Cancer ◽  
Radiation Induced

Gross hematuria is the most common presentation in genitourinary cancer patients. Patient with radiation cystitis also have similar presentation. Radiation cystitis can cause hematuria in various degrees, most of patients usually had mild to moderate degree which can be successfully treated with conservative treatment. In some patients, degree of hematuria may be severe that leads to mortality, correct treatment may decrease mortality rate. We review the current literature regarding the current management of radiation cystitis.

Intravesical Instillation of Dilute Formalin for the Treatment of Severe Hemorrhagic Emphysematous Cystitis in a Diabetic Dog

2004 ◽  
Vol 40 (1) ◽  
pp. 64-68 ◽  
Author(s):  
Todd D. Henrikson ◽  
Lisa Moore ◽  
David S. Biller ◽  
Thomas Schermerhorn
Keyword(s):  
Veterinary Medicine ◽  
Case Report ◽  
Urinary Bladder ◽  
Hemorrhagic Cystitis ◽  
Intravesical Instillation ◽  
Emphysematous Cystitis ◽  
Life Threatening ◽  
Diabetic Dog

Intravesical formalin is a known treatment for control of hemorrhagic cystitis caused by multiple etiologies in humans and dogs. This case report documents the successful use of intravesical formalin for the treatment of severe hemorrhagic cystitis that occurred secondary to emphysematous cystitis in a diabetic dog. In addition, a review of emphysematous cystitis and the use of intravesical formalin in human and veterinary medicine is discussed. Formalin instillation into the urinary bladder is an option for life-threatening, refractory cases of hemorrhagic cystitis; but clinicians must be familiar with the proper technique and be aware of potential complications prior to its use.

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