Simultaneous determination of cobalt and nickel. Comparison of prediction ability of PCR and PLS using original, first and second derivative spectra

Abstract A derivative spectrophotometric procedure was established for simultaneous determination of propranolol HCI (PP) with hydrochlorothiazide (HTZ) and metoprolol tartrate (MTP) with HTZ in tablet preparations. The method uses first- and second-derivative spectra of tablet extract in 0.01 N NaOH solution. Ratios of analyte concentrations in the mixture were determined by the compensation technique. The zero-crossing point (ZCP) was also used to estimate the amounts of PP and HTZ in the formulations, and results were compared with those from the compensation technique. The results were found to be precise and free from interferences.

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Simultaneous determination of aspirin and caffeine in the presence of pharmaceutical additives by curve fitting the second-derivative spectra.

BUNSEKI KAGAKU ◽

10.2116/bunsekikagaku.42.10_581 ◽

1993 ◽

Vol 42 (10) ◽

pp. 581-585 ◽

Cited By ~ 8

Author(s):

Keisuke KITAMURA ◽

Tatsuya KITADE ◽

Masanari MABUCHI ◽

Masaharu MIZUOCHI ◽

Koji GOTO

Keyword(s):

Simultaneous Determination ◽

Curve Fitting ◽

Second Derivative ◽

Derivative Spectra ◽

Second Derivative Spectra

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Simultaneous determination of compounds in Septalen® pellets by derivative spectrophotometry

Journal of the Serbian Chemical Society ◽

10.2298/jsc0006339m ◽

2000 ◽

Vol 65 (5-6) ◽

pp. 339-344 ◽

Cited By ~ 6

Author(s):

Mirjana Medenica ◽

Darko Ivanovic ◽

Andjelija Malenovic

Keyword(s):

Simultaneous Determination ◽

Regression Coefficient ◽

Correlation Coefficients ◽

The Other ◽

Second Derivative ◽

Zero Crossing ◽

Derivative Spectra ◽

Second Derivative Spectra ◽

Cetrimonium Bromide

In this paper, a second-derivative spectrophotometric method of assaying Septalen ? pellets (Krka, Novo Mesto, Slovenia), which contain lidocaine 1 mg, and cetrimoniumbromide 2mg, is described. Lidocaine, 2-(diethylamino)-N-(2,6-dimethyl- phenyl)-acetamide, is a local anesthetic with pronounced antiarhythmic and anticonvulsant properties. Cetrimoniumbromide, N,N,N-trimethyl-l-hexadecanaminium bromide, is a topical antiseptic and cleansing agent. Lidocaine was determined at 250 nm using the "zero crossing" technique because the signals of centrimonium bromide and the colour ingredient are zero at this wavelength. Cetrimonium bromide was determined by correction of the peak amplitude at 215 nm according to lidocaine. In choosing the optimal magnitudes for the simultaneous determination of both drugs, the following criteria were considered: (1) the linearity of the calibration graphs as given by the correlation coefficients, (2) the intercept, (3) the sensitivity as given by the regression coefficient, (4) the degree of interference in the derivative measurement by the presence of the other compound, as given by the relative percent error and by the relative recovery, and (5) the reproducibility, as given by the coefficient of variation, calculated by recording the second-derivative spectra.

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Multi-wavelength analyses of second-derivative spectra for rapid determination of acetaminophen in serum.

Clinical Chemistry ◽

10.1093/clinchem/34.6.1119 ◽

1988 ◽

Vol 34 (6) ◽

pp. 1119-1121 ◽

Cited By ~ 1

Author(s):

B Dingeon ◽

M A Charvin ◽

M T Quenard ◽

H Thome

Keyword(s):

Phosphate Buffer ◽

Rapid Determination ◽

Turnaround Time ◽

Second Derivative ◽

Derivative Spectra ◽

Multi Wavelength ◽

Precision And Accuracy ◽

Second Derivative Spectra ◽

Method Of Extraction

Abstract Measurement of acetaminophen by analysis of the second derivative of its spectrum is specific and sensitive. The method of extraction and the use of just one phosphate buffer as reagent makes this method very convenient. Readings are reliable from 10 to 1500 mg/L. A turnaround time of 20 min makes this method well suited for emergency cases. Precision and accuracy of the method are presented. Results are not biased by interferences, not even from N-acetylcysteine.

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Simultaneous Determination of Cobalt and Nickel Using Morpholinedithiocarbamate (MDTC) as Reagent by First and Second Derivative Spectrophotometry

Journal of the Chinese Chemical Society ◽

10.1002/jccs.200700102 ◽

2007 ◽

Vol 54 (3) ◽

pp. 715-722 ◽

Cited By ~ 4

Author(s):

Varinder Kaur ◽

Ashok Kumar Malika ◽

Neelam Verma

Keyword(s):

Simultaneous Determination ◽

Derivative Spectrophotometry ◽

Second Derivative ◽

Cobalt And Nickel

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Determination of Lipid Oxidation in Edible Oils by near Infrared Spectroscopy

Journal of Near Infrared Spectroscopy ◽

10.1255/jnirs.72 ◽

1995 ◽

Vol 3 (4) ◽

pp. 219-225 ◽

Cited By ~ 16

Author(s):

Hitoshi Takamura ◽

Noriko Hyakumoto ◽

Naoko Endo ◽

Teruyoshi Matoba ◽

Tamako Nishiike

Keyword(s):

Lipid Oxidation ◽

Near Infrared ◽

Edible Oils ◽

Lipid Peroxide ◽

Nir Spectroscopy ◽

Second Derivative ◽

Derivative Spectra ◽

Highly Correlated ◽

Second Derivative Spectra

The relationship between near infrared (NIR) second derivative spectra and lipid oxidation was investigated to develop a method for the determination of lipid oxidation in edible oils by NIR spectroscopy, using peroxide value ( POV) as the index of oxidation. Although several absorption peaks were found in the difference second derivative spectra of oxidised edible oils, the intensity of the peak at 2084 nm only was highly correlated to POV. In the spectra of purified hydroperoxides of methyl oleate and methyl linoleate, the intensity of the peak at 2084 nm was also highly correlated with POV, which demonstrates that the absorption is due to hydroperoxide. In addition, this peak shifted and weakened after reduction of hydroperoxide to hydroxide, which shows the absorption is specific for the hydroperoxyl group. These results suggest that 2084 nm is the key wavelength for lipid peroxide and can be used for the determination of lipid oxidation in edible oils.

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