The influence of lipophilic character on the biological activity of oligosaccharide antibiotics in Escherichia coli

1970 ◽  
Vol 2 (2) ◽  
pp. 121-124 ◽  
Author(s):  
Gian Luigi Biagi ◽  
Anna Maria Barbaro ◽  
Maria Clelia Guerra
Keyword(s):  
Escherichia Coli ◽  
Biological Activity ◽  
Lipophilic Character

scholarly journals Template Synthesis, Characterization and Biological Activity of Cu(II), Ni(II), Co(II), Zn(II)Complexes with Isonicotinoylhydrazone--2-aldehydefluorene Ligand

2010 ◽  
Vol 7 (1) ◽  
pp. 227-233
Keyword(s):  
Experimental Data ◽  
Escherichia Coli ◽  
Thermal Analysis ◽  
Biological Activity ◽  
Nmr Spectra ◽  
Magnetic Moments ◽  
Analytical Data ◽  
Azomethine Nitrogen ◽  
Tetrahedral Geometry ◽  
Metal Ligand

This is about synthesizing new complex combinations of Cu(II), Ni(II),Co(II), Zn(II) with aroylhydrazone ligand isonicotinoylhydrazone-2-aldehydefluorene (INHAF) made by condensation of isonicotinoylhydrazine with 2-aldehydefluorene. The complexes have been characterized by analytical data, IR, UV-Vis, NMR spectra, magnetic susceptibility values, thermal analysis and for the Cu(II) complex the ESR spectrum has been registered. For all complexes the biological activity against theStaphylo-coccus aureus, Escherichia coli, Klebssiella pneumoniaebacteria has been investigated. The experimental data sustain stoichiometry of 1:2 (metal/ligand) for the Cu(II), Ni(II), Zn(II) complexes and of 1:1 for the complex with Co(II). The electronic spectra and the magnetic moments suggest octahedral stereochemistry at the complexes with Cu(II), Ni(II) and the tetrahedral geometry for the Co(II) complex. The INHAF ligand is coordinated bidentate by the O=C amide oxygen and the azomethine nitrogen in the complexes of Cu(II), Ni(II), Co(II) and monodentate by the azomethine nitrogen in the complex of Zn(II).

scholarly journals Coexpression of interleukin-6 and -2 from giant panda in Escherichia coli and the biological activity of the fusion protein

2013 ◽  
Vol 12 (2) ◽  
pp. 1987-1995
Author(s):  
Y. Yi ◽  
Y.-Y. Nian ◽  
H.-W. Ji ◽  
H. Zhang ◽  
L. Zhu ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Biological Activity ◽  
Fusion Protein ◽  
Interleukin 6 ◽  
Giant Panda

scholarly journals Biological Activity of Escherichia coli tRNAPhe Modified in Its C-C-A Terminus

1972 ◽  
Vol 28 (4) ◽  
pp. 478-491 ◽  
Author(s):  
Jacov Tal ◽  
Uriel Z. Littauer ◽  
Murray P. Deutscher
Keyword(s):  
Escherichia Coli ◽  
Biological Activity

Biological activity of rat proinsulin synthesized by Escherichia coli

Gene ◽  
1983 ◽  
Vol 21 (1-2) ◽  
pp. 95-104 ◽  
Author(s):  
Stephen Naber ◽  
Lydia Villa-Komaroff ◽  
Stephanie Broome ◽  
Aldo Rossini ◽  
Vilma Lauris ◽  
...  
Keyword(s):  
Escherichia Coli ◽  
Biological Activity

scholarly journals Bioactive molecules modelised by numerical simulation:molecules against Escherichia Coli

2014 ◽  
Vol 70 (a1) ◽  
pp. C1008-C1008
Author(s):  
Rita Kakou Yao ◽  
Jules Abodou Tenon ◽  
Akoun Abou
Keyword(s):  
Escherichia Coli ◽  
Biological Activity ◽  
In Silico ◽  
Biological Activities ◽  
Digital Simulation ◽  
Simulation Method ◽  
Bioactive Molecules ◽  
Structural Determination ◽  
Human Beings

The work exposed in this paper joins in the research of medecine by means of the modelling by digital simulation (method in silico). This method allows to plan the biological activities of new molecules and to design others more active than existing molecules against a given infection . The generated and validated models are used here in the research for molecules potentially more active against Escherichia coli which causes diarrheic infections at the human beings. Here, we report works the synthesis of our works of structural determination, of forecast of biological activity and conception of molecules bioactive again Eschericha coli.

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