Pharmacology of natural compounds. I. Smooth muscle relaxant activity induced by a Ginkgo Biloba L. extract on guinea-pig trachea

1988 ◽  
Vol 20 (7) ◽  
pp. 573-589 ◽  
Author(s):  
L. Puglisi ◽  
S. Salvadori ◽  
G. Gabrielli ◽  
R. Pasargiklian
Keyword(s):  
Smooth Muscle ◽  
Guinea Pig ◽  
Ginkgo Biloba ◽  
Muscle Relaxant ◽  
Natural Compounds ◽  
Muscle Relaxant Activity ◽  
Smooth Muscle Relaxant

scholarly journals Triterpenoids, Including One with Smooth Muscle Relaxant Activity, from Rubus idaeus (Raspberry) Leaves

2006 ◽  
Vol 1 (8) ◽  
pp. 1934578X0600100
Author(s):  
Janne Rojas Vera ◽  
Christopher G. Dacke ◽  
Asmita V. Patel ◽  
Gerald Blunden
Keyword(s):  
Smooth Muscle ◽  
Guinea Pig ◽  
Column Chromatography ◽  
Muscle Relaxant ◽  
Methanol Extract ◽  
Rubus Idaeus ◽  
Guinea Pig Ileum ◽  
Muscle Relaxant Activity ◽  
Smooth Muscle Relaxant

A methanol extract of Rubus idaeus leaves was fractionated by column chromatography and the eluted samples were tested for their ability to relax transmurally stimulated Guinea pig ileum preparations in vitro. Two distinct bands of activity were detected. From band one sitosterol and eight triterpenoids were characterized, but only olean-18-ene-1β, 2α, 3α-triol demonstrated smooth muscle relaxant activity. This compound is, to the best of our knowledge, novel, as are olean-12-ene-3β, 29-diol and urs-12-ene-3β, 30-diol.

ChemInform Abstract: Synthesis and Smooth Muscle Relaxant Activity of a New Series of Potassium Channel Activators: 3-Amino-1,1-dimethylindan-2-ols.

ChemInform ◽  
2010 ◽  
Vol 22 (27) ◽  
pp. no-no
Author(s):  
D. R. BUCKLE ◽  
J. R. S. ARCH ◽  
C. EDGE ◽  
K. A. FOSTER ◽  
C. S. V. HOUGE-FRYDRYCH ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Potassium Channel ◽  
Muscle Relaxant ◽  
Muscle Relaxant Activity ◽  
Potassium Channel Activators ◽  
Smooth Muscle Relaxant

Synthesis and airway smooth muscle relaxant activity of linear and cyclic vasoactive intestinal peptide analogs

Peptides ◽  
1988 ◽  
pp. 441-443 ◽  
Author(s):  
David R. Bolin ◽  
Iou-Iou Sytwu ◽  
Jeanine M. Cottrell ◽  
Ralph J. Garippa ◽  
Cydney C. Brooks ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Vasoactive Intestinal Peptide ◽  
Airway Smooth Muscle ◽  
Muscle Relaxant ◽  
Peptide Analogs ◽  
Muscle Relaxant Activity ◽  
Smooth Muscle Relaxant

Smooth Muscle Relaxant Activity of Pterosin Z and Related Compounds

Planta Medica ◽  
1999 ◽  
Vol 65 (03) ◽  
pp. 271-272 ◽  
Author(s):  
Helen Sheridan ◽  
Neil Frankish ◽  
Ronan Farrell
Keyword(s):  
Smooth Muscle ◽  
Muscle Relaxant ◽  
Muscle Relaxant Activity ◽  
Related Compounds ◽  
Smooth Muscle Relaxant

Synthesis and smooth muscle relaxant activity of a new series of potassium channel activators: 3-amido-1,1-dimethylindan-2-ols

1991 ◽  
Vol 34 (3) ◽  
pp. 919-926 ◽  
Author(s):  
Derek R. Buckle ◽  
Jonathan R. S. Arch ◽  
Colin Edge ◽  
Keith A. Foster ◽  
Catherine S. V. Houge-Frydrych ◽  
...  
Keyword(s):  
Smooth Muscle ◽  
Potassium Channel ◽  
Muscle Relaxant ◽  
Muscle Relaxant Activity ◽  
Potassium Channel Activators ◽  
Smooth Muscle Relaxant
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