Wet granulation: the effect of shear on granule properties

Influence of spray nozzle aperture during high shear wet granulation on granule properties and its compression attributes

International Journal of Pharmaceutics ◽

10.1016/j.ijpharm.2018.10.067 ◽

2018 ◽

Vol 553 (1-2) ◽

pp. 474-482 ◽

Cited By ~ 5

Author(s):

Natalia Veronica ◽

Hui Ping Goh ◽

Christina Yong Xin Kang ◽

Celine Valeria Liew ◽

Paul Wan Sia Heng

Keyword(s):

Wet Granulation ◽

High Shear ◽

Spray Nozzle ◽

Real-time monitoring of granule properties during high shear wet granulation by near-infrared spectroscopy with a chemometrics approach

RSC Advances ◽

10.1039/c7ra05252a ◽

2017 ◽

Vol 7 (61) ◽

pp. 38307-38317 ◽

Cited By ~ 5

Author(s):

F. Shikata ◽

S. Kimura ◽

Y. Hattori ◽

M. Otsuka

Keyword(s):

Infrared Spectroscopy ◽

Real Time ◽

Near Infrared Spectroscopy ◽

Near Infrared ◽

Wet Granulation ◽

High Shear ◽

Monitoring Method ◽

Granulation Process ◽

An in-line near-infrared spectroscopy monitoring method was developed for analyzing granule properties during a high shear wet granulation process.

Twin screw wet granulation: Granule properties

Chemical Engineering Journal ◽

10.1016/j.cej.2010.05.023 ◽

2010 ◽

Vol 164 (2-3) ◽

pp. 322-329 ◽

Cited By ~ 89

Author(s):

Ranjit M. Dhenge ◽

Richard S. Fyles ◽

James J. Cartwright ◽

David G. Doughty ◽

Michael J. Hounslow ◽

...

Keyword(s):

Wet Granulation ◽

Twin Screw ◽

Predictive population balance model development and validation of the effect of high shear wet granulation process parameters on granule properties

Powder Technology ◽

10.1016/j.powtec.2018.07.004 ◽

2018 ◽

Vol 338 ◽

pp. 391-401 ◽

Cited By ~ 3

Author(s):

Anik Chaturbedi ◽

Preetanshu Pandey ◽

Dilbir Bindra ◽

Jay Poorna Reddy ◽

Bo Lang ◽

...

Keyword(s):

Process Parameters ◽

Model Development ◽

Balance Model ◽

Population Balance Model ◽

Wet Granulation ◽

High Shear ◽

Granulation Process ◽

Development And Validation ◽

Comparison of granule properties produced using Twin Screw Extruder and High Shear Mixer: A step towards understanding the mechanism of twin screw wet granulation

Powder Technology ◽

10.1016/j.powtec.2012.05.031 ◽

2013 ◽

Vol 238 ◽

pp. 91-98 ◽

Cited By ~ 48

Author(s):

Kai T. Lee ◽

Andy Ingram ◽

Neil A. Rowson

Keyword(s):

Wet Granulation ◽

High Shear ◽

Twin Screw Extruder ◽

Screw Extruder ◽

Twin Screw ◽

Effect of Physical States of Binders on High-Shear Wet Granulation and Granule Properties: A Mechanistic Approach Toward Understanding High-Shear wet Granulation Process, Part 3: Effect of Binder Rheological Properties

10.1002/jps.23059 ◽

2012 ◽

Vol 101 (5) ◽

pp. 1877-1887 ◽

Cited By ~ 7

Author(s):

Jinjiang Li ◽

Li Tao ◽

David Buckley ◽

Jing Tao ◽

Julia Gao ◽

...

Keyword(s):

Rheological Properties ◽

Wet Granulation ◽

High Shear ◽

Granulation Process ◽

Mechanistic Approach ◽

Twin screw wet granulation: Influence of formulation parameters on granule properties and growth behavior

Powder Technology ◽

10.1016/j.powtec.2012.04.035 ◽

2013 ◽

Vol 238 ◽

pp. 108-115 ◽

Cited By ~ 121

Author(s):

A.S. El Hagrasy ◽

J.R. Hennenkamp ◽

M.D. Burke ◽

J.J. Cartwright ◽

J.D. Litster

Keyword(s):

Growth Behavior ◽

Wet Granulation ◽

Twin Screw ◽

Formulation Parameters ◽

The Effect of the Physical States of Binders on High-Shear Wet Granulation and Granule Properties: A Mechanistic Approach Towards Understanding High-Shear Wet Granulation Process. Part I. Physical Characterization of Binders

10.1002/jps.22260 ◽

2011 ◽

Vol 100 (1) ◽

pp. 164-173 ◽

Cited By ~ 12

Author(s):

Jinjiang Li ◽

Li Tao ◽

Mandar Dali ◽

David Buckley ◽

Julia Gao ◽

...

Keyword(s):

Physical Characterization ◽

Wet Granulation ◽

High Shear ◽

Granulation Process ◽

Mechanistic Approach ◽

The Effect of the Physical States of Binders on High-Shear Wet Granulation and Granule Properties: A Mechanistic Approach Toward Understanding High-Shear Wet Granulation Process. Part II. Granulation and Granule Properties

10.1002/jps.22261 ◽

2011 ◽

Vol 100 (1) ◽

pp. 294-310 ◽

Cited By ~ 14

Author(s):

Jinjiang Li ◽

Li Tao ◽

Mandar Dali ◽

David Buckley ◽

Julia Gao ◽

...

Keyword(s):

Wet Granulation ◽

High Shear ◽

Granulation Process ◽

Mechanistic Approach ◽

The Effect of the Physical State of Binders on High-Shear Wet Granulation and Granule Properties: A Mechanistic Approach to Understand the High-Shear Wet Granulation Process. Part IV. The Impact of Rheological State and Tip-speeds

10.1002/jps.23750 ◽

2013 ◽

Vol 102 (12) ◽

pp. 4384-4394 ◽

Cited By ~ 3

Author(s):

Jinjiang Li ◽

Li Tao ◽

David Buckley ◽

Jing Tao ◽

Julia Gao ◽

...

Keyword(s):

Physical State ◽

Wet Granulation ◽

High Shear ◽

Granulation Process ◽

Mechanistic Approach ◽

The Impact ◽