Influence of spray nozzle aperture during high shear wet granulation on granule properties and its compression attributes

Real-time monitoring of granule properties during high shear wet granulation by near-infrared spectroscopy with a chemometrics approach

RSC Advances ◽

10.1039/c7ra05252a ◽

2017 ◽

Vol 7 (61) ◽

pp. 38307-38317 ◽

Cited By ~ 5

Author(s):

F. Shikata ◽

S. Kimura ◽

Y. Hattori ◽

M. Otsuka

Keyword(s):

Infrared Spectroscopy ◽

Real Time ◽

Near Infrared Spectroscopy ◽

Near Infrared ◽

Wet Granulation ◽

High Shear ◽

Monitoring Method ◽

Granulation Process ◽

An in-line near-infrared spectroscopy monitoring method was developed for analyzing granule properties during a high shear wet granulation process.

Predictive population balance model development and validation of the effect of high shear wet granulation process parameters on granule properties

Powder Technology ◽

10.1016/j.powtec.2018.07.004 ◽

2018 ◽

Vol 338 ◽

pp. 391-401 ◽

Cited By ~ 3

Author(s):

Anik Chaturbedi ◽

Preetanshu Pandey ◽

Dilbir Bindra ◽

Jay Poorna Reddy ◽

Bo Lang ◽

...

Keyword(s):

Process Parameters ◽

Model Development ◽

Balance Model ◽

Population Balance Model ◽

Wet Granulation ◽

High Shear ◽

Granulation Process ◽

Development And Validation ◽

Effect of Physical States of Binders on High-Shear Wet Granulation and Granule Properties: A Mechanistic Approach Toward Understanding High-Shear wet Granulation Process, Part 3: Effect of Binder Rheological Properties

10.1002/jps.23059 ◽

2012 ◽

Vol 101 (5) ◽

pp. 1877-1887 ◽

Cited By ~ 7

Author(s):

Jinjiang Li ◽

Li Tao ◽

David Buckley ◽

Jing Tao ◽

Julia Gao ◽

...

Keyword(s):

Rheological Properties ◽

Wet Granulation ◽

High Shear ◽

Granulation Process ◽

Mechanistic Approach ◽

The Effect of the Physical States of Binders on High-Shear Wet Granulation and Granule Properties: A Mechanistic Approach Towards Understanding High-Shear Wet Granulation Process. Part I. Physical Characterization of Binders

10.1002/jps.22260 ◽

2011 ◽

Vol 100 (1) ◽

pp. 164-173 ◽

Cited By ~ 12

Author(s):

Jinjiang Li ◽

Li Tao ◽

Mandar Dali ◽

David Buckley ◽

Julia Gao ◽

...

Keyword(s):

Physical Characterization ◽

Wet Granulation ◽

High Shear ◽

Granulation Process ◽

Mechanistic Approach ◽

The Effect of the Physical States of Binders on High-Shear Wet Granulation and Granule Properties: A Mechanistic Approach Toward Understanding High-Shear Wet Granulation Process. Part II. Granulation and Granule Properties

10.1002/jps.22261 ◽

2011 ◽

Vol 100 (1) ◽

pp. 294-310 ◽

Cited By ~ 14

Author(s):

Jinjiang Li ◽

Li Tao ◽

Mandar Dali ◽

David Buckley ◽

Julia Gao ◽

...

Keyword(s):

Wet Granulation ◽

High Shear ◽

Granulation Process ◽

Mechanistic Approach ◽

The Effect of the Physical State of Binders on High-Shear Wet Granulation and Granule Properties: A Mechanistic Approach to Understand the High-Shear Wet Granulation Process. Part IV. The Impact of Rheological State and Tip-speeds

10.1002/jps.23750 ◽

2013 ◽

Vol 102 (12) ◽

pp. 4384-4394 ◽

Cited By ~ 3

Author(s):

Jinjiang Li ◽

Li Tao ◽

David Buckley ◽

Jing Tao ◽

Julia Gao ◽

...

Keyword(s):

Physical State ◽

Wet Granulation ◽

High Shear ◽

Granulation Process ◽

Mechanistic Approach ◽

The Impact ◽

Efficient Global Sensitivity-Based Model Calibration of a High-Shear Wet Granulation Process

Chemical Engineering Science ◽

10.1016/j.ces.2021.116569 ◽

2021 ◽

pp. 116569

Author(s):

Aaron S. Yeardley ◽

Stefan Bellinghausen ◽

Robert Milton ◽

James D. Litster ◽

Solomon F. Brown

Keyword(s):

Model Calibration ◽

Wet Granulation ◽

High Shear ◽

Granulation Process ◽

Global Sensitivity ◽

High Shear Wet Granulation

A combined experimental and modeling approach to study the effects of high-shear wet granulation process parameters on granule characteristics

Pharmaceutical Development and Technology ◽

10.3109/10837450.2012.700933 ◽

2012 ◽

Vol 18 (1) ◽

pp. 210-224 ◽

Cited By ~ 40

Author(s):

Preetanshu Pandey ◽

Jing Tao ◽

Anwesha Chaudhury ◽

Rohit Ramachandran ◽

Julia Z. Gao ◽

...

Keyword(s):

Process Parameters ◽

Wet Granulation ◽

High Shear ◽

Granulation Process ◽

Modeling Approach ◽

High Shear Wet Granulation

Optimization of a high shear wet granulation process using focused beam reflectance measurement and particle vision microscope technologies

10.1002/jps.22556 ◽

2011 ◽

Vol 100 (8) ◽

pp. 3431-3440 ◽

Cited By ~ 15

Author(s):

Zane Arp ◽

Ben Smith ◽

Eric Dycus ◽

Des O'grady

Keyword(s):

Wet Granulation ◽

High Shear ◽

Reflectance Measurement ◽

Granulation Process ◽

Focused Beam

High shear wet granulation: Improved understanding of the effects of process variables on granule and tablet properties of a high-dose, high-hydrophobicity API based on quality by design and multivariate analysis approaches

Advanced Powder Technology ◽

10.1016/j.apt.2021.11.021 ◽

2021 ◽

Author(s):

Binbin Liu ◽

Jiamiao Wang ◽

Qin Zhou ◽

Lijie Zhao ◽

Youjie Wang ◽

...

Keyword(s):

Multivariate Analysis ◽

Quality By Design ◽

Wet Granulation ◽

High Dose ◽

High Shear ◽

Process Variables ◽

Tablet Properties ◽

High Shear Wet Granulation