Application to drug–food interactions of living cells as in vitro model expressing cytochrome P450 activity: enzyme inhibition by lemon juice

Talanta ◽  
2001 ◽  
Vol 54 (5) ◽  
pp. 983-987 ◽  
Author(s):  
M Baltes
Keyword(s):  
Cytochrome P450 ◽  
Enzyme Inhibition ◽  
In Vitro Model ◽  
Living Cells ◽  
Lemon Juice ◽  
Cytochrome P450 Activity ◽  
Vitro Model ◽  
P450 Activity

Monitoring mRNA in living cells in a 3D in vitro model using TAT-peptide linked molecular beacons

Lab on a Chip ◽  
2011 ◽  
Vol 11 (22) ◽  
pp. 3908 ◽  
Author(s):  
Jennifer Claire Alexander ◽  
Abhay Pandit ◽  
Gang Bao ◽  
David Connolly ◽  
Yury Rochev
Keyword(s):  
In Vitro Model ◽  
Living Cells ◽  
Molecular Beacons ◽  
Tat Peptide ◽  
3D In Vitro Model ◽  
Vitro Model

HepG2 cells as an in vitro model for evaluation of cytochrome P450 induction by xenobiotics

2014 ◽  
Vol 38 (5) ◽  
pp. 691-704 ◽  
Author(s):  
Jong Min Choi ◽  
Soo Jin Oh ◽  
Sang Yoon Lee ◽  
Ji Hye Im ◽  
Jung Min Oh ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Hepg2 Cells ◽  
In Vitro Model ◽  
Cytochrome P450 Induction ◽  
Vitro Model

In Vitro Cytochrome P450 Activity Decreases in Children with High Pediatric End-Stage Liver Disease Scores

2012 ◽  
Vol 41 (2) ◽  
pp. 390-397 ◽  
Author(s):  
Lies De Bock ◽  
Koen Boussery ◽  
Myriam Van Winckel ◽  
Peter De Paepe ◽  
Xavier Rogiers ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
Liver Disease ◽  
End Stage Liver Disease ◽  
Cytochrome P450 Activity ◽  
End Stage ◽  
P450 Activity

Mediation of in Vitro Cytochrome P450 Activity by Common Pharmaceutical Excipients

2013 ◽  
Vol 10 (7) ◽  
pp. 2739-2748 ◽  
Author(s):  
Philip Martin ◽  
Marco Giardiello ◽  
Tom O. McDonald ◽  
Steven P. Rannard ◽  
Andrew Owen
Keyword(s):  
Cytochrome P450 ◽  
Pharmaceutical Excipients ◽  
Cytochrome P450 Activity ◽  
P450 Activity

Utility of Long-Term Cultured Human Hepatocytes as an in Vitro Model for Cytochrome P450 Induction

2006 ◽  
Vol 35 (2) ◽  
pp. 215-220 ◽  
Author(s):  
Georgina Meneses-Lorente ◽  
Christine Pattison ◽  
Claire Guyomard ◽  
Christophe Chesné ◽  
Robert Heavens ◽  
...  
Keyword(s):  
Cytochrome P450 ◽  
In Vitro Model ◽  
Human Hepatocytes ◽  
Cytochrome P450 Induction ◽  
Vitro Model
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