Mental Disorder and Violent Victimization in a Total Birth Cohort

BackgroundPsychotropic medication use is common and increasing. Use of such drugs at the individual level over long periods has not been reported.AimsTo describe antidepressant, anxiolytic and hypnotic drug use, and associations between such medication use and common mental disorder, over a 22-year period.MethodQuestions about psychotropic medication use and symptoms of common mental disorder were asked of more than 3000 members of the 1946 British birth cohort at multiple time points between ages 31 and 53 years.ResultsPrevalence of any antidepressant, anxiolytic or hypnotic use increased significantly from 1977 (30.6 per 1000) to 1999 (59.1 per 1000) as the cohort aged. Less than 30% with mental disorder used antidepressants, anxiolytics or hypnotics. Previous use of antidepressant, anxiolytic or hypnotic was a strong predictor of future use during an episode of mental disorder (odds ratios 3.0–8.4); this association became weaker over time.ConclusionsPharmacotherapy is infrequently used by individuals with common mental disorder in Britain; this has not changed in the past three decades.

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Difficulty in making contact with others and social withdrawal as early signs of psychosis in adolescents – the Northern Finland Birth Cohort 1986

European Psychiatry ◽

10.1016/j.eurpsy.2013.11.003 ◽

2014 ◽

Vol 29 (6) ◽

pp. 345-351 ◽

Cited By ~ 8

Author(s):

P. Mäki ◽

S. Koskela ◽

G.K. Murray ◽

T. Nordström ◽

J. Miettunen ◽

...

Keyword(s):

General Population ◽

Mental Disorder ◽

Birth Cohort ◽

Psychotic Disorders ◽

Social Withdrawal ◽

Population Based ◽

Clinical Samples ◽

First Episode ◽

Control Group ◽

Episode Psychosis

AbstractAimSocial withdrawal is among the first signs of the prodromal state of psychosis seen in clinical samples. The aim of this prospective study was to find out whether difficulty in making contact with others and social withdrawal precede first episode psychosis in the young general population.MethodsThe members of the Northern Finland Birth Cohort 1986 (n = 6274) completed the PROD-screen questionnaire in 2001–2002. The Finnish Hospital Discharge Register was used to detect both new psychotic and non-psychotic disorders requiring hospitalisation during 2003–2008.ResultsTwenty-three subjects developed psychosis and 89 developed a non-psychotic mental disorder requiring hospitalisation during the follow-up. Of those who developed psychosis, 35% had reported difficulty or uncertainty in making contact with others and 30% social withdrawal in adolescence. In hospitalised non-psychotic disorder, the corresponding precentages were 10 and 13% and in the control group without hospital-treated mental disorder 9 and 11%. The differences between psychotic and non-psychotic hospitalised subjects (P < 0.01) as well as controls (P < 0.001) were statistically significant regarding difficulty or uncertainty in making contact with others.ConclusionsIn this general population-based sample self-reported difficulty or uncertainty in making contact with others in adolescence preceded psychosis specifically compared to hospitalised non-psychotic mental disorders and controls.

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Mental disorder diagnoses of offspring affected by parental cancer before early adulthood: the 1987 Finnish Birth Cohort study

Psycho-Oncology ◽

10.1002/pon.4088 ◽

2016 ◽

Vol 25 (12) ◽

pp. 1477-1484 ◽

Cited By ~ 10

Author(s):

Mika Niemelä ◽

Reija Paananen ◽

Helinä Hakko ◽

Marko Merikukka ◽

Mika Gissler ◽

...

Keyword(s):

Cohort Study ◽

Mental Disorder ◽

Birth Cohort ◽

Early Adulthood ◽

Birth Cohort Study ◽

Parental Cancer

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T127. OFFSPRING OF ANTENATALLY DEPRESSED MOTHERS AND PARENTS WITH SEVERE MENTAL DISORDER – A LONG FOLLOW-UP IN THE NORTHERN FINLAND 1966 BIRTH COHORT

Schizophrenia Bulletin ◽

10.1093/schbul/sby016.403 ◽

2018 ◽

Vol 44 (suppl_1) ◽

pp. S164-S165

Author(s):

Pirjo Mäki ◽

Tiina Taka-Eilola ◽

Graham Murray ◽

Juha Veijola

Keyword(s):

Mental Disorder ◽

Birth Cohort ◽

Severe Mental Disorder ◽

Depressed Mothers

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Mental disorder and violent victimization

PsycEXTRA Dataset ◽

10.1037/e511622010-005 ◽

2009 ◽

Keyword(s):

Mental Disorder ◽

Violent Victimization

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Intelligence and criminal behavior in a total birth cohort: An examination of functional form, dimensions of intelligence, and the nature of offending

Intelligence ◽

10.1016/j.intell.2015.06.001 ◽

2015 ◽

Vol 51 ◽

pp. 109-118 ◽

Cited By ~ 25

Author(s):

Joseph A. Schwartz ◽

Jukka Savolainen ◽

Mikko Aaltonen ◽

Marko Merikukka ◽

Reija Paananen ◽

...

Keyword(s):

Birth Cohort ◽

Criminal Behavior ◽

Functional Form ◽

Total Birth

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Substance use Disorder in the Offspring of Antenatally Depressed Mothers in the Northern Finland 1966 Birth Cohort: Relationship to Parental History of Severe Mental Disorder

European Psychiatry ◽

10.1016/j.eurpsy.2017.02.025 ◽

2017 ◽

Vol 41 (S1) ◽

pp. s246-s246

Author(s):

P. Mäki ◽

T. Taka-Eilola ◽

J. Veijola

Keyword(s):

Substance Use ◽

Mental Disorder ◽

Maternal Depression ◽

Birth Cohort ◽

Substance Use Disorder ◽

Antenatal Depression ◽

Severe Mental Disorder ◽

Parental History ◽

Increased Risk ◽

Depressed Mothers

IntroductionMaternal depression during pregnancy is common. However, reports of the adult offspring with maternal antenatal depression are scarce.ObjectivesOur aim was to study whether offspring of antenatally depressed mothers have increased risk for substance use disorder when taking account parental mental disorder.MethodsIn the Northern Finland 1966 Birth Cohort, the mothers of 12,058 children were asked at the antenatal clinic if they felt depressed. The offspring were followed for over 40 years. Substance use disorders were detected using the Finnish Care Register for Health Care, which was also used for identifying severe mental disorders in the parents till 1984.ResultsOf the mothers, 14% had rated themselves as depressed during pregnancy. Of the parents, 10% had had a hospital-treated mental disorder. The risk for substance use disorder was slightly increased in the offspring of antenatally depressed mothers (crude OR 1.6; 95% CI 1.2–2.1), when compared with the cohort members without maternal antenatal depression. The risk for substance use disorder was higher in the offspring with both maternal antenatal depression and parental mental disorder (2.8; 1.7–4.7) than in those with maternal depression but without parental mental disorder (1.4; 1.1–2.0) or those without maternal depression and with parental mental disorder (1.5; 1.1–2.2). The reference group was cohort members without maternal antenatal depression and without parental mental disorder. The association remained significant after adjustment [1].ConclusionsOffspring with both maternal depression during pregnancy and parental severe mental disorder have elevated risk for substance use disorder.Disclosure of interestThe authors have not supplied their declaration of competing interest.

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