Vesl/Homer proteins regulate ryanodine receptor type 2 function and intracellular calcium signaling

Cell Calcium ◽  
2003 ◽  
Vol 34 (3) ◽  
pp. 261-269 ◽  
Author(s):  
Jens H Westhoff ◽  
Sung-Yong Hwang ◽  
R Scott Duncan ◽  
Fumiko Ozawa ◽  
Pompeo Volpe ◽  
...  
2020 ◽  
Vol 11 (1) ◽  
Author(s):  
Matthew Sermersheim ◽  
Adam D. Kenney ◽  
Pei-Hui Lin ◽  
Temet M. McMichael ◽  
Chuanxi Cai ◽  
...  

Author(s):  
FRANK CH. MOOREN ◽  
ANJA LECHTERMANN ◽  
ALBERT FROMME ◽  
LOTHAR THORWESTEN ◽  
KLAUS V??LKER

2012 ◽  
Vol 198 (1) ◽  
pp. 7-10 ◽  
Author(s):  
Ilya Bezprozvanny

Mutations in presenilins (PS), transmembrane proteins encoding the catalytic subunit of γ-secretase, result in familial Alzheimer’s disease (FAD). Several studies have identified lysosomal defects in cells lacking PS or expressing FAD-associated PS mutations, which have been previously attributed to a function for PS in lysosomal acidification. Now, in this issue, Coen et al. (2012. J. Cell Biol. http://dx.doi.org/10.1083/jcb.201201076) provide a series of results that challenge this idea and propose instead that presenilins play a role in calcium-mediated lysosomal fusion.


2005 ◽  
Vol 80 (1) ◽  
pp. 135-145 ◽  
Author(s):  
Clayton S. Spada ◽  
Achim H.-P. Krauss ◽  
David F. Woodward ◽  
June Chen ◽  
Charles E. Protzman ◽  
...  

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