Neurological soft signs in adolescents with poor performance on the continuous performance test: markers of liability for schizophrenia spectrum disorders?

1999 ◽  
Vol 86 (3) ◽  
pp. 217-228 ◽  
Author(s):  
Jordi E. Obiols ◽  
Francisco Serrano ◽  
Beatriu Caparrós ◽  
Susana Subirá ◽  
Neus Barrantes
2006 ◽  
Vol 115 (4) ◽  
pp. 771-778 ◽  
Author(s):  
Matthew T. Avila ◽  
Olalla Robles ◽  
L. Elliot Hong ◽  
Theresa A. Blaxton ◽  
Carol S. Myers ◽  
...  

2019 ◽  
Vol 210 ◽  
pp. 101-106 ◽  
Author(s):  
Stefan Fritze ◽  
Alina L. Bertolino ◽  
Katharina M. Kubera ◽  
Cristina E. Topor ◽  
Mike M. Schmitgen ◽  
...  

2019 ◽  
Vol 34 (6) ◽  
pp. 868-868
Author(s):  
S Sarkissians ◽  
A Hauson ◽  
N Stelmach ◽  
A Walker ◽  
A Pollard ◽  
...  

Abstract Objective Heroin dependent individuals appear to have significant deficits in attention which can be assessed using digit span forward (DSF) or the continuous performance test (CPT). The current meta-analysis examined differences between DSF and CPT results in studies of heroin dependent participants. Data selection Two researchers independently searched nine databases (e.g., PsycINFO, Pubmed, ProceedingsFirst), extracted required data, and calculated effect sizes. Inclusion criteria identified studies that had (a) compared heroin-dependent groups to healthy controls and (b) matched groups on either age, education, or IQ (at least 2 out of 3). Studies were excluded if participants were reported to have Axis I diagnoses (other than heroin dependence) or comorbidities known to impact neuropsychological functioning. Ten articles were coded and analyzed for the current study. Data synthesis When examined together, DSF and CPT evidenced a moderate and statistically significant effect size estimate (g = 0.614, p = .002). Subgroup analysis did not reveal statistically significant differences between the two groups (Q-Between = 0.228, p = 0.633). The effect size for DSF was g = 0.535 (p = 0.001) and for CPT was g = 0.774 (p = 0.104). The heterogeneity of DSF was in the moderate range, I2 = 71.291%, p = 0.002 while the heterogeneity of CPT was in the large range I2 = 97.863%, p = 0.001. Conclusion Heroin dependent individuals appear to demonstrate similarly poor performance on DSF and CPT. Assuming that both tests measure the same construct, both appear to be sensitive to the effect of Heroin on attention.


1992 ◽  
Vol 71 (3_suppl) ◽  
pp. 1131-1136 ◽  
Author(s):  
Jordi E. Obiols ◽  
Margarida Clos ◽  
Eulalia Corberó ◽  
Mercè García-Domingo ◽  
Isabel de Trinchería ◽  
...  

We studied groups of 39 schizophrenic subjects, 35 schizotypic subjects, and 33 control subjects, comparing them on a standard sustained attention task called the Continuous Performance Test (identical pairs version). The expected negative relationship between performance on sustained attention and psychopathology was confirmed by differences among the three groups which were in the direction predicted, although only the difference between the schizophrenic group and the other two groups was significant. This finding adds evidence to the view from research on high risk and attention with schizophrenic subjects that subtle attention deficits are present among subjects within the schizophrenia spectrum. Consequently, our results can be understood as supporting a dimensional theory of psychopathology.


2015 ◽  
Vol 42 (3) ◽  
pp. 560-570 ◽  
Author(s):  
Raymond C. K. Chan ◽  
Weizhen Xie ◽  
Fu-lei Geng ◽  
Ya Wang ◽  
Simon S. Y. Lui ◽  
...  

2020 ◽  
Vol 31 ◽  
pp. 47-57 ◽  
Author(s):  
Stefan Fritze ◽  
Fabio Sambataro ◽  
Katharina M. Kubera ◽  
Alina L. Bertolino ◽  
Cristina E. Topor ◽  
...  

Author(s):  
K. Hennighausen ◽  
G. Schulte-Körne ◽  
A. Warnke ◽  
H. Remschmidt

Zusammenfassung Fragestellung: Gibt es neurophysiologische Korrelate der Aufmerksamkeitsstörung beim hyperkinetischen Syndrom (HKS) und welche Bedeutung haben diese für die Ätiologie der Störung. Methodik: Selektive Aufmerksamkeitsprozesse wurden anhand des zweistufigen Continuous Performance Test (CPT) bei 18 Jungen mit hyperkinetischem Syndrom (HKS) untersucht und mit einer nach dem Alter parallelisierten Kontrollgruppe von 21 Jungen verglichen. Die Altersspanne der Stichprobe betrug 6 bis 12 Jahre. Parallel dazu wurden ereigniskorrelierte Potentiale (EKP) während des Tests an den Elektrodenpositionen Fz, Cz, Pz und Oz mit Referenz zu verbundenen Ohren abgeleitet. Ergebnisse: Im EKP nach dem präparatorischen Stimulus konnten zwei Komponenten der Contingent Negative Variation (CNV) mit unterschiedlicher topographischer Verteilung identifiziert werden (CNV-1: 600 bis 1100 ms und CNV-2: 1000 bis 1500 ms nach Stimulus). Die Stichproben unterschieden sich nicht auf der Verhaltensebene (Fehlerrate und Reaktionszeit). Signifikante Gruppenunterschiede ergaben sich hinsichtlich der Topographie der beiden CNV-Komponenten. Kinder mit HKS zeigten im Vergleich zu Kontrollkindern eine signifikant niedrigere CNV-1 über der frontalen und eine Tendenz zu stärkerer Negativierung (CNV-1 und CNV-2) über der occipitalen Elektrode. Schlussfolgerungen: Die Ergebnisse unterstützen die Hypothese einer Unterfunktion frontaler inhibitorischer Prozesse bei Kindern mit HKS.


2016 ◽  
Vol 32 (4) ◽  
pp. 291-297 ◽  
Author(s):  
Dubi Lufi ◽  
Shachar Pan

Abstract. Several studies have shown that Continuous Performance Tests (CPT) can diagnose Attention Deficit Hyperactivity Disorder (ADHD) better than other tests. Research reporting comparisons of two or more CPT-type tests is scarce. The purpose of the study was to compare the Mathematics Continuous Performance Test (MATH-CPT) with another CPT-type test (CPT II) and a questionnaire (the Brown Scale). The comparison was carried out by looking at correlations among subscales and checking the precision of detecting ADHD. Ninety-five high school and college students participated in the study, 41 with ADHD were the research group and 54 were the control group. The participants performed the two tests and answered the questionnaire. The results showed that the MATH-CPT correctly identified 74.50% of the participants of both groups as compared to the 71.60% of the CPT II. Correlations between the two CPT-type tests were moderate; however, they were similar to correlations found in other studies comparing similar tools. The MATH-CPT, final attention formula, showed significant correlations with the Brown scales, while the CPT II, confidence index associated with ADHD assessment, showed nonsignificant correlations with the questionnaire. The study indicated that MATH-CPT can be used with a clinical population of ADHD and for research purposes.


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