Different effects of acute neonatal stressors and long-term postnatal handling on stress-induced changes in behavior and in ornithine decarboxylase activity of adult rats

2000 ◽  
Vol 120 (2) ◽  
pp. 255-259 ◽  
Author(s):  
Varda H Gilad ◽  
Jose M Rabey ◽  
Yishai Eliyayev ◽  
Gad M Gilad
1979 ◽  
Vol 237 (1) ◽  
pp. E6
Author(s):  
G Scalabrino ◽  
M E Ferioli ◽  
M Basagni ◽  
R Nebuloni ◽  
F Fraschini

The activities of ornithine and S-adenosyl-L-methionine decarboxylase were assayed in the thymuses of adult rats killed at 7-day intervals up to 6 wk after either pinealectomy or sham pinealectomy. The absence of the pineal gland markedly influenced the ornithine decarboxylase activity in the thymus, in which the level of the enzyme was decreased permanently by the 4th wk after the operation (P less than 0.05). The time course of the changes in S-adenosyl-L-methionine decarboxylase activity in the thymus during the entire period investigated was also significantly (P less than 0.05) modified by pinealectomy but did not show any stable trend. Adrenalectomy significantly raised (P less than 0.001) for ornithine decarboxylase; P less than 0.01 for S-adenosyl-L-methionine decarboxylase) the basal levels of the thymic biosynthetic polyamine decarboxylases. A pharmacological dose of corticosterone or cortisol produced a rapid and significant decrease in ornithine and S-adenosyl-L-methionine decarboxylase activities (P less than 0.02) in the thymus, whereas the injection of either D-aldosterone or ACTH was ineffective. Therefore, the thymic biosynthetic polyamine decarboxylases that in this organ are known to be located only in the lymphocytes appear to be regulated in opposing ways by the pineal gland and by the adrenal cortex.


Biochemistry ◽  
1973 ◽  
Vol 12 (16) ◽  
pp. 3072-3076 ◽  
Author(s):  
A. M. Kaye ◽  
I. Icekson ◽  
S. A. Lamprecht ◽  
Rosemarie Gruss ◽  
A. Tsafriri ◽  
...  

1978 ◽  
Vol 39 (02) ◽  
pp. 496-503 ◽  
Author(s):  
P A D’Amore ◽  
H B Hechtman ◽  
D Shepro

SummaryOrnithine decarboxylase (ODC) activity, the rate-limiting step in the synthesis of polyamines, can be demonstrated in cultured, bovine, aortic endothelial cells (EC). Serum, serotonin and thrombin produce a rise in ODC activity. The serotonin-induced ODC activity is significantly blocked by imipramine (10-5 M) or Lilly 11 0140 (10-6M). Preincubation of EC with these blockers together almost completely depresses the 5-HT-stimulated ODC activity. These observations suggest a manner by which platelets may maintain EC structural and metabolic soundness.


2007 ◽  
Vol 53 (1) ◽  
pp. 1-9 ◽  
Author(s):  
YUTAKA HOSHINO ◽  
SHINYA TERASHIMA ◽  
YASUSHI TERANISHI ◽  
MASANORI TERASHIMA ◽  
MICHIHIKO KOGURE ◽  
...  

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