scholarly journals Partitioning a matrix with non-guillotine cuts to minimize the maximum cost

2002 ◽  
Vol 116 (3) ◽  
pp. 243-260 ◽  
Author(s):  
Aristide Mingozzi ◽  
Serena Morigi
Keyword(s):  
2020 ◽  
Vol 15 ◽  
Author(s):  
Billu Payal ◽  
Anoop Kumar ◽  
Harsh Saxena

Background: Asthma and Chronic Obstructive Pulmonary Diseases (COPD) are well known respiratory diseases affecting millions of peoples in India. In the market, various branded generics, as well as generic drugs, are available for their treatment and how much cost will be saved by utilizing generic medicine is still unclear among physicians. Thus, the main aim of the current investigation was to perform cost-minimization analysis of generic versus branded generic (high and low expensive) drugs and branded generic (high expensive) versus branded generic (least expensive) used in the Department of Pulmonary Medicine of Era Medical University, Lucknow for the treatment of asthma and COPD. Methodology: The current index of medical stores (CIMS) was referred for the cost of branded drugs whereas the cost of generic drugs was taken from Jan Aushadi scheme of India 2016. The percentage of cost variation particularly to Asthma and COPD regimens on substituting available generic drugs was calculated using standard formula and costs were presented in Indian Rupees (as of 2019). Results: The maximum cost variation was found between the respules budesonide high expensive branded generic versus least expensive branded generic drugs and generic versus high expensive branded generic. In combination, the maximum cost variation was observed in the montelukast and levocetirizine combination. Conclusion: In conclusion, this study inferred that substituting generic antiasthmatics and COPD drugs can bring potential cost savings in patients.


Energies ◽  
2021 ◽  
Vol 14 (15) ◽  
pp. 4675
Author(s):  
Ayat-allah Bouramdane ◽  
Alexis Tantet ◽  
Philippe Drobinski

In this study, we examine how Battery Storage (BES) and Thermal Storage (TES) combined with solar Photovoltaic (PV) and Concentrated Solar Power (CSP) technologies with an increased storage duration and rental cost together with diversification would influence the Moroccan mix and to what extent the variability (i.e., adequacy risk) can be reduced; this is done using recent (2013) cost data and under various penetration scenarios. To do this, we use MERRA-2 climate reanalysis to simulate hourly demand and capacity factors (CFs) of wind, solar PV and CSP without and with increasing storage capabilities—as defined by the CSP Solar Multiple (SM) and PV Inverter Loading Ratio (ILR). We adjust these time series to observations for the four Moroccan electrical zones over the year 2018. Our objective is to maximize the renewable (RE) penetration and minimize the imbalances between RE production and consumption considering three optimization strategies. We analyze mixes along Pareto fronts using the Mean-Variance Portfolio approach—implemented in the E4CLIM model—in which we add a maximum-cost constraint to take into account the different rental costs of wind, PV and CSP. We propose a method to calculate the rental cost of storage and production technologies taking into account the constraints on storage associated with the increase of SM and ILR in the added PV-BES and CSP-TES modules, keeping the mean solar CFs fixed. We perform some load bands-reduction diagnostics to assess the reliability benefits provided by each RE technology. We find that, at low penetrations, the maximum-cost budget is not reached because a small capacity is needed. The higher the ILR for PV, the larger the share of PV in the mix compared to wind and CSP without storage is removed completely. Between PV-BES and CSP-TES, the latter is preferred as it has larger storage capacity and thus stronger impact in reducing the adequacy risk. As additional BES are installed, more than TES, PV-BES is favored. At high penetrations, optimal mixes are impacted by cost, the more so as CSP (resp., PV) with high SM (resp., ILR) are installed. Wind is preferably installed due to its high mean CF compared to cost, followed by either PV-BES or CSP/CSP-TES. Scenarios without or with medium storage capacity favor CSP/CSP-TES, while high storage duration scenarios are dominated by low-cost PV-BES. However, scenarios ignoring the storage cost and constraints provide more weight to PV-BES whatever the penetration level. We also show that significant reduction of RE variability can only be achieved through geographical diversification. Technological complementarity may only help to reduce the variance when PV and CSP are both installed without or with a small amount of storage. However, the diversification effect is slightly smaller when the SM and ILR are increased and the covariances are reduced as well since mixes become less diversified.


This paper provides the management methods of AC & DC smart grids. AC smart grids square measure a convenient approach to integration distributed energy systems with utility power systems. Smart grid may be a arrangement of smart generators, fuel cell, storage systems and masses. DC micro grids will cause additional economical integration of distributed generation. The methods of smart grids measure completely by the management of converters. In solar panel maximum cost utilized in storage systems like battery. In this paper a latest method has been recommended to replace the battery with fuel cell. Stored hydrogen used as a fuel which generate electricity. In this type of hydrogen storage system efficiency is not more than 55 percentages. This paper explaining about the scheme of the management methods of converter and the management methods of smart grids in each AC & DC conditions


Author(s):  
Alexander Yakovlev

Today is the time of transnational corporations and large companies. They bring to their shareholders and owners the major profits, and they are the main sponsors of scientific and technological progress. However, the extensive way of its development is not possible for environmental, marketing, resource, and many other reasons. So, the main field of competition between companies becomes a fight for the client, the individualization of approach to him, and the maximum cost reduction. At the same time, a series of scandals that erupted in the early 2000s with such major corporations as Enron Corporation, WorldCom, Tyco International, Adelphia, and Peregrine Systems has shown that the system of corporate governance, on which depends the welfare of hundreds of thousands of people, requires serious improvements in terms of transparency and openness. In this regard, the U.S. adopted the Sarbanes-Oxley Act of 2002, under which management companies legally obliged to prove that his decisions are based on reliable, relevant, credible and accurate information (Devenport & Harris, 2010).


Author(s):  
Irving Streimer

The paper develops a methodological approach to the sizing of man-machine systems which is predicated upon the efficiency of conversion of available system energy into useful goal directed work. Systems are generically categorized into two classes as a function of their energy replacement characteristics. Four classes of energy conversion efficiency degradations are delineated which can adversely affect system capability, reliability, and cost. The effects of alterations in operator performance characteristics upon system design are detailed in terms of engineering changes, and suggestions are advanced as to the nature of the future research necessary to obtain maximum cost effectiveness in future systems.


2020 ◽  
pp. 667-678 ◽  
Author(s):  
Omoruyi Credit Irabor ◽  
William Swanson ◽  
Fiza Shaukat ◽  
Johanna Wirtz ◽  
Abba Aji Mallum ◽  
...  

PURPOSE The limited radiotherapy resources for global cancer control have resulted in increased interest in developing time- and cost-saving innovations to expand access to those resources. Hypofractionated regimens could minimize cost and increase access for limited-resource countries. In this investigation, we estimated the percentage cost-savings per radiotherapy course and increased radiotherapy access in African countries after adopting hypofractionation for breast and prostate radiotherapy. For perspective, results were compared with high-income countries. METHODS The cost and course of breast and prostate radiotherapy for conventional and hypofractionated regimens in low-resource facilities were calculated using the Radiotherapy Cost Estimator tool developed by the International Atomic Energy Agency (IAEA) and then compared with another activity-based costing model. The potential maximum cost savings in each country over 7 years for breast and prostate radiotherapy were then estimated using cancer incidence data from the Global Cancer Observatory database with use rates applied. The increase in radiotherapy access was estimated by current national capacities from the IAEA directory. RESULTS The estimated cost per course of conventional and hypofractionated regimens were US$2,232 and $1,339 for breast treatment, and $3,389 and $1,699 for prostate treatment, respectively. The projected potential maximum cost savings with full hypofractionation implementation were $1.1 billion and $606 million for breast and prostate treatment, respectively. The projected increase of radiotherapy access due to implementing hypofractionation varied between +0.3% to 25% and +0.4% to 36.0% for breast and prostate treatments, respectively. CONCLUSION This investigation demonstrates that adopting hypofractionated regimens as standard treatment of breast and prostate cancers can result in substantial savings and increase radiotherapy access in developing countries. Given reduced delivery cost and treatment times, we anticipate a substantial increase in radiotherapy access with additional innovations that will allow progressive hypofractionation without compromising quality.


Sign in / Sign up

Export Citation Format

Share Document