10 oral MRI-based treatment planning in cervix carcinoma; its impact on the conformality of the treatment

2002 ◽  
Vol 63 ◽  
pp. S4
2002 ◽  
Vol 10 (4) ◽  
pp. 253-259 ◽  
Author(s):  
Milutin Baucal ◽  
Jovan Babic ◽  
Zoran Kuzmanovic

BACKGROUND: Brachytherapy of cervix carcinoma often results in high doses to surrounding structures, such as rectum and bladder. Therefore, these organs should be closely monitored. Purpose of this work was to evaluate rectal marker made in our institution for rectal dose measurements by comparing it with the method recommended in ICRU (International Commission on Radiation Units and Measurements) Report 38. METHODS: In this work rectal dosimetry was performed by two different methods. In one, rectal marker made in Institute of Oncology Sremska Kamenica was used, while in the other method recommended in ICRU Report 38 dose on ICRU rectal point was measured A total of 34 applications using Microselectron HDR and its standard applicator set were performed in a prospective way. The prescribed dose was 7.6 Gy to point A for each application. Rectal doses were calculated by Nucletron Plato Treatment Planning System. RESULTS: Differences found between the means of ICRU point R and rectal marker points Rref and Rmax were significant (P<0.002 and P<0.00002). The same result was obtained for Rref and Rmax pair (P<0.003). CONCLUSION: Maximal doses obtained using rectal marker were in most cases high- er than those obtained by ICRU method. It conforms well to several CT-based dosimetry studies where rectum dose was found to be higher from that obtained by ICRU method.


Author(s):  
S Srivastava ◽  
N K Painuly ◽  
S P Mishra ◽  
K Srivastava ◽  
N Singh ◽  
...  

Background: Brachytherapy treatment planning in cervix carcinoma patients using two dimensional (2D) orthogonal images provides only point dose estimates while CT-based planning provides volumetric dose assessment helping in understanding the correlation between morbidity and the dose to organs at risk (OARs) and treatment volume.Objective: Aim of present study is to compare International Commission on Radiation Units and Measurements Report 38 (ICRU 38) reference point doses to OARs with volumetric doses using 2D images and CT images in patients with cervical cancer.Material and Methods: In this prospective study, 20 patients with cervical cancer stages (IIB-IIIB) were planned for a brachytherapy dose of 7Gy per fraction for three fractions using 2D image-based treatment plan and CT-based plan. ICRU 38 points for bladder and rectum were identified on both 2D image-based plan and CT-based plan and doses (DICRU) at these points were compared to the minimum dose to 2cc volume (D2cc) of bladder and rectum receiving the highest dose.Results: D2cc bladder dose was 1.60 (±0.67) times more than DICRUb bladder dose whereas D2cc rectum dose was 1.13±0.40 times DICRUr. Significant difference was found between DICRUb and D2cc dose for bladder (p=.0.016) while no significant difference was seen between DICRUr and D2cc dose for rectum (p=0.964).Conclusion: The study suggests that ICRU 38 point doses are not the true representation of maximum doses to OARs. CT-based treatment planning is more a reliable tool for OAR dose assessment than the conventional 2D radiograph-based plan.


2005 ◽  
Vol 173 (4S) ◽  
pp. 412-412
Author(s):  
Ashutosh Tewari ◽  
Assaad El-Hakim ◽  
Peter N. Schlegel ◽  
Mani Menon ◽  
Deirdre M. Coll

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