PO-1728: Development of a new prompt gamma ray detection system for full 3D proton range verification

2020 ◽  
Vol 152 ◽  
pp. S957-S958
Author(s):  
P. Costanza ◽  
R.I. Mackay ◽  
K.J. Kirkby ◽  
M.J. Taylor
2021 ◽  
Author(s):  
Valerie Nwadeyi ◽  
Paul maggi ◽  
Zhong He ◽  
Jerimy Polf

This manuscript discusses the use of a large volume array CZT detector for experimental prompt gamma-ray imaging. Namely, the 718 keV and the 4.44 MeV photopeaks produced from proton-carbon interactions are imaged using maximum likelihood expectation maximization (MLEM). Various proton beam irradiations are used to characterize the feasibility of using both photopeaks for beam range verification.


2014 ◽  
Vol 41 (6Part29) ◽  
pp. 495-495
Author(s):  
J Verburg ◽  
M Testa ◽  
E Cascio ◽  
T Bortfeld ◽  
H Lu ◽  
...  

2015 ◽  
Vol 42 (6Part27) ◽  
pp. 3548-3548
Author(s):  
J Verburg ◽  
T Bortfeld ◽  
J Seco

2021 ◽  
Author(s):  
Valerie Nwadeyi ◽  
Paul maggi ◽  
Zhong He ◽  
Jerimy Polf

This manuscript discusses the use of a large volume array CZT detector for experimental prompt gamma-ray imaging. Namely, the 718 keV and the 4.44 MeV photopeaks produced from proton-carbon interactions are imaged using maximum likelihood expectation maximization (MLEM). Various proton beam irradiations are used to characterize the feasibility of using both photopeaks for beam range verification.


2019 ◽  
Vol 62 ◽  
pp. 20-32 ◽  
Author(s):  
Melek Zarifi ◽  
Susanna Guatelli ◽  
Yujin Qi ◽  
David Bolst ◽  
Dale Prokopovich ◽  
...  

2021 ◽  
Author(s):  
Valerie Nwadeyi ◽  
Paul maggi ◽  
Zhong He ◽  
Jerimy Polf

<p><i>Position sensitive CdZnTe Compton imaging cameras are currently being studied for their use of proton beam range verification for radiotherapy applications. This work presents the use of an experimental large volume CdZnTe detector for the detection of prompt gamma rays that are emitted from proton-nuclei interaction within plastic (C2H4) targets. Two experiments were conducted where the incident angle and the dose profile of the beam were varied. The energy spectra from these experiments show that the angle at which the beam enters the target can influence the photopeak to Compton continuum ratios, resulting in more than 18% increase at 718 keV when the beam is parallel to the detector. Images of the 718 keV and 4.44 MeV characteristic prompt gamma ray emission from carbon-proton interactions are reconstructed using list-mode maximum likelihood expectation maximization (MLEM). Images from these prompt gamma emissions line up well with the expected location of the proton beam within the plastic targets.</i><br></p>


2021 ◽  
Author(s):  
Valerie Nwadeyi ◽  
Paul maggi ◽  
Zhong He ◽  
Jerimy Polf

This manuscript discusses the use of a large volume array CZT detector for experimental prompt gamma-ray imaging. Namely, the 718 keV and the 4.44 MeV photopeaks produced from proton-carbon interactions are imaged using maximum likelihood expectation maximization (MLEM). Various proton beam irradiations are used to characterize the feasibility of using both photopeaks for beam range verification.


2019 ◽  
Vol 216 ◽  
pp. 03005
Author(s):  
Michele Riva ◽  
Elia A. Vallicelli ◽  
Andrea Baschirotto ◽  
Marcello De Matteis

Proton range verification by ionoacoustic wave sensing is a technique under development for applications in adron therapy as an alternative to nuclear imaging. It provides an acoustic imaging of the proton energy deposition vs. depth using the acoustic wave Time of Flight (ToF). State-of-the-art (based on simulations and experimental results) points out that this detection technique achieves better spatial resolution (< 1 mm) of the proton range comparing with Positron-Emission-Tomography (PET) and prompt gamma ray techniques. This work presents a complete Geant4/k-Wave model that allows to understand several physical phenomena and to evaluate the key parameters that affect the acoustic field generated by the incident proton radiation.


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