Phosphatidylinositol-3 kinase and extracellular signal-regulated kinase mediate the chemotactic and mitogenic effects of insulin-like growth factor-I in human hepatic stellate cells

Extracellular Signal Regulated Kinase ◽

Factor I ◽

Extracellular Signal ◽

Growth Factor I ◽

Expression of insulin-like growth factor I by activated hepatic stellate cells reduces fibrogenesis and enhances regeneration after liver injury

Gut ◽

10.1136/gut.2003.024505 ◽

2005 ◽

Vol 54 (1) ◽

pp. 134-141 ◽

Cited By ~ 59

Author(s):

S Sanz

Keyword(s):

Growth Factor ◽

Liver Injury ◽

Hepatic Stellate Cells ◽

Stellate Cells ◽

Factor I ◽

Growth Factor I ◽

Activated Hepatic Stellate Cells

Evaluation of intracellular signalling pathways in response to insulin-like growth factor I in apoptotic-resistant activated human hepatic stellate cells

Fibrogenesis & Tissue Repair ◽

10.1186/1755-1536-2-1 ◽

2009 ◽

Vol 2 (1) ◽

Cited By ~ 21

Author(s):

Alessandra Gentilini ◽

Benedetta Lottini ◽

Marco Brogi ◽

Alessandra Caligiuri ◽

Lorenzo Cosmi ◽

...

Keyword(s):

Growth Factor ◽

Hepatic Stellate Cells ◽

Stellate Cells ◽

Intracellular Signalling ◽

Signalling Pathways ◽

Factor I ◽

Intracellular Signalling Pathways ◽

Growth Factor I

Insulin like growth factor-I induces limited association of phosphatidylinositol 3-kinase to its receptor.

Endocrinology ◽

10.1210/endo.130.3.1311242 ◽

1992 ◽

Vol 130 (3) ◽

pp. 1490-1498 ◽

Cited By ~ 2

Author(s):

K Yamamoto ◽

E G Lapetina ◽

C P Moxham

Keyword(s):

Growth Factor ◽

Factor I ◽

Growth Factor I ◽

The Phosphatidylinositol-3 kinase Pathway Is Not Essential for Insulin-like Growth Factor I Receptor-mediated Clonogenic Radioresistance

Journal of Radiation Research ◽

10.1269/jrr.43.325 ◽

2002 ◽

Vol 43 (3) ◽

pp. 325-329 ◽

Cited By ~ 3

Author(s):

DONG YU ◽

HIROSHI WATANABE ◽

HITOSHI SHIBUYA ◽

MASAHIKO MIURA

Keyword(s):

Growth Factor ◽

Factor I ◽

Growth Factor I ◽

Kinase Pathway ◽

Insulin-Like Growth Factor-I Regulates Proliferation and Osteoblastic Differentiation of Calcifying Vascular Cells via Extracellular Signal-Regulated Protein Kinase And Phosphatidylinositol 3-Kinase Pathways

Circulation Research ◽

10.1161/01.res.0000157671.47477.71 ◽

2005 ◽

Vol 96 (4) ◽

pp. 398-400 ◽

Cited By ~ 77

Author(s):

Kristen Radcliff ◽

Tri-Bang Tang ◽

Jina Lim ◽

Zina Zhang ◽

Moeen Abedin ◽

...

Keyword(s):

Growth Factor ◽

Protein Kinase ◽

Osteoblastic Differentiation ◽

Vascular Cells ◽

Factor I ◽

Extracellular Signal ◽

Growth Factor I ◽

Calcifying Vascular Cells

Insulin-like Growth Factor-I Inhibits Transcriptional Responses of Transforming Growth Factor-β by Phosphatidylinositol 3-Kinase/Akt-dependent Suppression of the Activation of Smad3 but Not Smad2

Journal of Biological Chemistry ◽

10.1074/jbc.m304583200 ◽

2003 ◽

Vol 278 (40) ◽

pp. 38342-38351 ◽

Cited By ~ 76

Author(s):

Kyung Song ◽

Susan C. Cornelius ◽

Michael Reiss ◽

David Danielpour

Keyword(s):

Growth Factor ◽

Transforming Growth Factor ◽

Transforming Growth Factor Β ◽

Transcriptional Responses ◽

Factor I ◽

Growth Factor I ◽

Insulin-Like Growth Factor-I Inhibits Dexamethasone-Induced Catabolism in Cultured L6 Myotubes by Activation of Phosphatidylinositol 3-Kinase

Journal of Burn Care & Rehabilitation ◽

10.1097/00004630-200303002-00195 ◽

2003 ◽

Vol 24 ◽

pp. S140

Author(s):

&NA;

Keyword(s):

Growth Factor ◽

Factor I ◽

L6 Myotubes ◽

Growth Factor I ◽

Insulin like growth factor-I induces limited association of phosphatidylinositol 3-kinase to its receptor

Endocrinology ◽

10.1210/en.130.3.1490 ◽

1992 ◽

Vol 130 (3) ◽

pp. 1490-1498 ◽

Cited By ~ 10

Author(s):

K. Yamamoto

Keyword(s):

Growth Factor ◽

Factor I ◽

Growth Factor I ◽

Mitogen-Activated Protein Kinase and Phosphatidylinositol 3-Kinase Pathways Are Not Sufficient for Insulin-Like Growth Factor I-Induced Mitogenesis and Tumorigenesis

Endocrinology ◽

10.1210/endo.138.6.5215 ◽

1997 ◽

Vol 138 (6) ◽

pp. 2552-2558 ◽

Cited By ~ 15

Author(s):

Angus G. Scrimgeour ◽

Vicky A. Blakesley ◽

Bethel S. Stannard ◽

Derek LeRoith

Keyword(s):

Growth Factor ◽

Protein Kinase ◽

Mitogen Activated Protein Kinase ◽

Factor I ◽

Mitogen Activated Protein ◽

Growth Factor I ◽

Phosphatidylinositol 3-Kinase (PI3K) Activity Bound to Insulin-like Growth Factor-I (IGF-I) Receptor, which Is Continuously Sustained by IGF-I Stimulation, Is Required for IGF-I-induced Cell Proliferation

Journal of Biological Chemistry ◽

10.1074/jbc.m112.393074 ◽

2012 ◽

Vol 287 (35) ◽

pp. 29713-29721 ◽

Cited By ~ 19

Author(s):

Toshiaki Fukushima ◽

Yusaku Nakamura ◽

Daisuke Yamanaka ◽

Takashi Shibano ◽

Kazuhiro Chida ◽

...

Keyword(s):

Cell Proliferation ◽

Growth Factor ◽

Factor I ◽

Pi3k Activity ◽

Igf I ◽

Growth Factor I ◽