[414] STUDY ON THE EXPRESSION OF TOLL-LIKE RECEPTOR 3 (TLR3) ON DENDRITIC CELLS DERIVED FROM PERIPHERAL BLOOD MONOCYTE OF CHRONIC HEPATITIS B PATIENTS

2007 ◽  
Vol 46 ◽  
pp. S159 ◽  
Author(s):  
G.F. Shi ◽  
M.Q. Chen ◽  
Q. Li
Keyword(s):  
Dendritic Cells ◽  
Chronic Hepatitis ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Peripheral Blood ◽  
Peripheral Blood Monocyte ◽  
Blood Monocyte ◽  
Toll Like Receptor

scholarly journals Reduced Expression of Toll-Like Receptor 2 on Peripheral Monocytes in Patients with Chronic Hepatitis B

2006 ◽  
Vol 13 (8) ◽  
pp. 972-974 ◽  
Author(s):  
Stephen M. Riordan ◽  
Narelle Skinner ◽  
Jelica Kurtovic ◽  
Stephen Locarnini ◽  
Kumar Visvanathan
Keyword(s):  
Chronic Hepatitis ◽  
Hepatitis B ◽  
Chronic Hepatitis B ◽  
Persistent Infection ◽  
Peripheral Blood Monocyte ◽  
Toll Like Receptor ◽  
Wild Type ◽  
Viral Inhibition ◽  
B Virus ◽  
Toll Like Receptor 2

ABSTRACT Persistent infection with hepatitis B virus (HBV) likely depends on viral inhibition of host defenses. We report that chronic hepatitis B e antigen-positive HBV infection is associated with a significant reduction in peripheral blood monocyte expression of Toll-like receptor 2, a key component of innate immunity, thereby providing a mechanism by which wild-type HBV may establish persistent infection.

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