Improving the Results of Ganglion Aspiration by the Use of Hyaluronidase

We present the results of a prospective randomized trial comparing the treatment of ganglia by aspiration under local anaesthetic and either instillation of steroid alone or with the prior use of hyaluronidase. Thirty-five patients were treated in each group and followed up for 2 years. The cure rate with the combined use of hyaluronidase and methylprednisolone was 89%, compared to 57% when treated by aspiration and instillation of methylprednisolone alone.

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920 THE EFFECT OF THE COMBINED USE OF L-MENTHOL SPRAYING AND CARBON DIOXIDE INSUFFLATION ON THE ADENOMA DETECTION RATE DURING COLONOSCOPY: A PROSPECTIVE, RANDOMIZED TRIAL

Gastrointestinal Endoscopy ◽

10.1016/j.gie.2018.04.1328 ◽

2018 ◽

Vol 87 (6) ◽

pp. AB125-AB126 ◽

Cited By ~ 1

Author(s):

Ken Inoue ◽

Takashi Okuda ◽

Kohei Oka ◽

Satoshi Sugino ◽

Toshifumi Tsuji ◽

...

Keyword(s):

Carbon Dioxide ◽

Randomized Trial ◽

Detection Rate ◽

Adenoma Detection Rate ◽

Prospective Randomized Trial ◽

Carbon Dioxide Insufflation ◽

Combined Use ◽

Adenoma Detection

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Propofol Injection Pain: Comparing the Addition of Lignocaine or Metoclopramide

Anaesthesia and Intensive Care ◽

10.1177/0310057x9402200511 ◽

1994 ◽

Vol 22 (5) ◽

pp. 568-570 ◽

Cited By ~ 20

Author(s):

D. W. J. Mecklem

Keyword(s):

Randomized Trial ◽

Local Anaesthetic ◽

Lower Incidence ◽

Haemodynamic Effects ◽

Prospective Randomized Trial ◽

Injection Pain ◽

Pain On Injection ◽

Extrapyramidal Reaction ◽

Recovery Times ◽

A Minor

Lignocaine has been shown to reduce the incidence of pain on injection of propofol. Metoclopramide, a weak local anaesthetic and commonly used antiemetic, was combined with propofol and the mixture compared, in a prospective, randomized trial, with a lignocaine-propofol combination. The incidence of injection pain was similar in both groups, as were recovery times and incidence of vomiting. The metoclopramide-propofol group experienced a lower incidence of nausea. One patient in the metoclopramide-propofol group had a minor extrapyramidal reaction. No adverse local or haemodynamic effects were seen.

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Scabies in Koranic schools in Dakar, Senegal: Comparison of two therapeutic modalities

Public Health of Indonesia ◽

10.36685/phi.v7i4.456 ◽

2021 ◽

Vol 7 (4) ◽

pp. 172-181

Author(s):

Ly Fatimata ◽

Faye Adama ◽

Wone Issa ◽

Lelo Souleye ◽

Diouf Astou ◽

...

Keyword(s):

Randomized Trial ◽

Optimal Treatment ◽

Tropical Disease ◽

Prospective Randomized Trial ◽

Neglected Tropical Disease ◽

Cure Rate ◽

Benzyl Benzoate ◽

Therapeutic Modalities ◽

Significant Difference ◽

The Mean

Background: In 2017, WHO recognized scabies as a neglected tropical disease. The optimal treatment is not well defined in some communities.Objective: This study aimed to compare ivermectin and benzyl benzoate in the treatment of scabies in Koranic schools (or "daara") in Dakar (region).Methods: This was a prospective randomized trial conducted from January to October 2018 in Senegal. Any resident living in the selected "daara" and diagnosed with scabies was included. The administered treatments were benzyl benzoate (BB) or ivermectin. At the outset, if one case of scabies was diagnosed, all residents received treatment. Ivermectin was given at the dose of 200 mg/kg. The same treatment was repeated on day 7 for each group, the endpoint was at D14, and the data were analyzed with STATA 14.Results: Fifteen "daara" were included. Of the 959 residents, 70 were diagnosed with scabies: prevalence of 7.29%. All patients except one were male; the mean age was 9.98 years (4-17). At D14, in the BB arm, cure rate was 42.85% (n = 15) while in the ivermectin arm, this rate was 5.71% (n = 2) with a significant difference (p = 0.01). On D28, the cure rate was still higher in the BB group 57.14 (n=20) versus ivermectin 21.42 (n = 6) with a significant difference (p = 0.004). On D42, all patients except eight were cured. At D14, we found a link between the cure rate, the number of people in the room (p = 0.01), and the number of showers per week (p = 0.01) but no link with the number of people per "daara" (p = 0.163). At D28, we found a link between the cure rate, the number of people sleeping in the room (p = 0.03), and the number of showers per week (p = 0.01) but not with the number of people per "daara" (p = 0.07).Conclusion: In Koranic schools, the cure rate is higher with benzyl benzoate compared to ivermectin.

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