Expression of super cervical ganglion-10 (SCG-10) mRNA in the monkey cerebral cortex during postnatal development

2002 ◽  
Vol 323 (3) ◽  
pp. 199-202 ◽  
Author(s):  
Takao Oishi ◽  
Noriyuki Higo ◽  
Keiji Matsuda ◽  
Motoharu Hayashi
Keyword(s):  
Cerebral Cortex ◽  
Postnatal Development ◽  
Cervical Ganglion

scholarly journals Localization of CGRP and VEGF mRNAs in the mouse superior cervical ganglion during pre- and postnatal development

2018 ◽  
Vol 62 (4) ◽  
Author(s):  
Kazuyuki Mitsuoka ◽  
Yoko Miwa ◽  
Takeshi Kikutani ◽  
Iwao Sato
Keyword(s):  
In Situ Hybridization ◽  
Postnatal Development ◽  
Blood Supply ◽  
Superior Cervical Ganglion ◽  
Prenatal Development ◽  
Antisense Probe ◽  
Calcitonin Gene ◽  
Cervical Ganglion ◽  
Endothelial Growth Factor

The neuropeptide calcitonin gene-related peptide (CGRP) mediates inflammation and head pain by influencing the functional vascular blood supply. CGRP is a well-characterized mediator of receptor-regulated neurotransmitter release. However, knowledge regarding the role of CGRP during the development of the superior cervical ganglion (SCG) is limited. In the present study, we observed the localization of CGRP and vascular endothelial growth factor (VEGF-A) mRNAs during prenatal development at embryonic day 14.5 (E14.5), E17.5 and postnatal day 1 (P1) using in situ hybridization. The antisense probe for CGRP was detected by in situ hybridization at E14.5, E17.5, and P1, and the highest levels were detected at E17.5. In contrast, the antisense probe for VEGF-A was detected by in situ hybridization in gradually increasing intensity from E14.5 to P1. The differences in the expression of these two markers revealed specific characteristics related to CGRP concentration and release compared to those of VEGF-A during development. The correlation between CGRP and VEGF-A may influence functional stress and the vascular blood supply during prenatal and postnatal development.

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