Granule cell dendritic spine density in the rat hippocampus varies with spine shape and location

1985 ◽  
Vol 54 (2-3) ◽  
pp. 219-224 ◽  
Author(s):  
Nancy L. Desmond ◽  
William B. Levy
Keyword(s):  
Granule Cell ◽  
Dendritic Spine ◽  
Rat Hippocampus ◽  
Spine Density ◽  
Spine Shape ◽  
Dendritic Spine Density

scholarly journals 3P220 Activin A acutely increases dendritic spine density in rat hippocampus

2004 ◽  
Vol 44 (supplement) ◽  
pp. S244
Author(s):  
K. Mitsuhashi ◽  
H. Mukai ◽  
Y. Hojo ◽  
M. Asashima ◽  
A. Fukui ◽  
...  
Keyword(s):  
Dendritic Spine ◽  
Activin A ◽  
Rat Hippocampus ◽  
Spine Density ◽  
Dendritic Spine Density

scholarly journals Effect of tibolone on dendritic spine density in the rat hippocampus

2015 ◽  
Vol 30 (7) ◽  
pp. 401-406 ◽  
Author(s):  
V. Beltrán-Campos ◽  
A. Díaz-Ruiz ◽  
E. Padilla-Gómez ◽  
H. Aguilar Zavala ◽  
C. Ríos ◽  
...  
Keyword(s):  
Dendritic Spine ◽  
Rat Hippocampus ◽  
Spine Density ◽  
Dendritic Spine Density

scholarly journals The Effects of Cocaine Self-Administration on Dendritic Spine Density in the Rat Hippocampus Are Dependent on Genetic Background

2013 ◽  
Vol 25 (1) ◽  
pp. 56-65 ◽  
Author(s):  
Miguel Miguéns ◽  
Asta Kastanauskaite ◽  
Santiago M. Coria ◽  
Abraham Selvas ◽  
Inmaculada Ballesteros-Yañez ◽  
...  
Keyword(s):  
Dendritic Spine ◽  
Genetic Background ◽  
Rat Hippocampus ◽  
Spine Density ◽  
Self Administration ◽  
Dendritic Spine Density

scholarly journals Simultaneous Changes of Spatial Memory and Spine Density after Intrahippocampal Administration of Fibrillar Aβ1–42to the Rat Brain

2014 ◽  
Vol 2014 ◽  
pp. 1-9 ◽  
Author(s):  
Emőke Borbély ◽  
János Horváth ◽  
Szabina Furdan ◽  
Zsolt Bozsó ◽  
Botond Penke ◽  
...  
Keyword(s):  
Spatial Memory ◽  
Dendritic Spine ◽  
Density Measurement ◽  
Rat Hippocampus ◽  
Learning Ability ◽  
Spine Density ◽  
Ca1 Region ◽  
Dendritic Spine Density ◽  
Intrahippocampal Injection ◽  
The Brain

Several animal models of Alzheimer’s disease have been used in laboratory experiments. Intrahippocampal injection of fibrillar amyloid-beta (fAβ) peptide represents one of the most frequently used models, mimicking Aβdeposits in the brain. In our experiment synthetic fAβ1–42peptide was administered to rat hippocampus. The effect of the Aβpeptide on spatial memory and dendritic spine density was studied. The fAβ1–42-treated rats showed decreased spatial learning ability measured in Morris water maze (MWM). Simultaneously, fAβ1–42caused a significant reduction of the dendritic spine density in the rat hippocampus CA1 region. The decrease of learning ability and the loss of spine density were in good correlation. Our results prove that both methods (MWM and dendritic spine density measurement) are suitable for studying Aβ-triggered neurodegeneration processes.

scholarly journals FMRP regulates the subcellular distribution of cortical dendritic spine density in a non-cell-autonomous manner

2021 ◽  
pp. 105253
Author(s):  
Katherine M. Bland ◽  
Adam Aharon ◽  
Eden L. Widener ◽  
M. Irene Song ◽  
Zachary O. Casey ◽  
...  
Keyword(s):  
Dendritic Spine ◽  
Subcellular Distribution ◽  
Spine Density ◽  
Dendritic Spine Density
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