Effect of customized small bowel displacement system in pelvic irradiation

1998 ◽  
Vol 40 (3) ◽  
pp. 623-627 ◽  
Author(s):  
Seung Jae Huh ◽  
Do Hoon Lim ◽  
Yong Chan Ahn ◽  
Dae Yong Kim ◽  
Moon Kyung Kim ◽  
...  
Keyword(s):  
Small Bowel ◽  
Pelvic Irradiation ◽  
Displacement System

scholarly journals Radiation-Induced Emesis (RIE) in Extended-Field Radiotherapy for Gynecological Malignancies: Dosimetric and Non-Dosimetric Factors

2021 ◽  
Vol 28 (5) ◽  
pp. 3602-3609
Author(s):  
Yu-Ming Wang ◽  
Yi-Fan Chen ◽  
Pei-Yi Lee ◽  
Meng-Wei Ho ◽  
Eng-Yen Huang
Keyword(s):  
Logistic Regression ◽  
Small Bowel ◽  
Early Onset ◽  
Independent Factor ◽  
Pelvic Radiotherapy ◽  
Pelvic Irradiation ◽  
Gynecological Malignancies ◽  
Radiation Induced ◽  
Extended Field

Radiation-induced emesis (RIE) is usually noted during abdominal-pelvic radiotherapy. In gynecological malignancies, it is usually noted in para-aortic but not whole-pelvic irradiation. Irradiated small bowel (SB) may be associated with RIE. The significance of SB dosimetry remains unclear. Dosimetric and non-dosimetric factors were evaluated and correlated with RIE in 45 patients with gynecological malignancies undergoing extended-field radiotherapy (EFRT) (median 45 Gy) from 2006 to 2021. Early-onset RIE (within 72 h after the first fraction of EFRT) was noted in 10 of 12 RIE patients. RIE was significantly associated with the SB mean dose. The RIE rates were 58.3% and 15.2% (p = 0.007) in patients with a low (<63%) and high (≥63%) SB mean dose. Logistic regression revealed that the SB mean dose remained the independent factor of overall RIE (p = 0.049) and early-onset RIE (p = 0.014). Therefore, constraint of the SB mean dose limited to less than 63% of the prescribed dose is suggested to decrease RIE.

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