Advances in cell separation: recent developments in counterflow centrifugal elutriation and continuous flow cell separation

1999 ◽  
Vol 722 (1-2) ◽  
pp. 55-69 ◽  
Author(s):  
Johann Bauer
Keyword(s):  
Continuous Flow ◽  
Cell Separation ◽  
Flow Cell ◽  
Centrifugal Elutriation ◽  
Recent Developments

scholarly journals Principles of blood separation and component extraction in a disposable continuous-flow single-stage channel

Blood ◽  
1979 ◽  
Vol 54 (1) ◽  
pp. 254-268 ◽  
Author(s):  
JP Hester ◽  
RM Kellogg ◽  
AP Mulzet ◽  
VR Kruger ◽  
KB McCredie ◽  
...  
Keyword(s):  
Whole Blood ◽  
Continuous Flow ◽  
Cell Separation ◽  
Flow Cell ◽  
Buffy Coat ◽  
Single Stage ◽  
Flow Rates ◽  
Blood Separation ◽  
Final Yield ◽  
Component Extraction

Abstract A single-stage disposable channel and seal that provides for leukocyte and granulocyte collection by continuous-flow cell separation (CFCS) has been designed by the IBM Corporation. This paper describes (1) the separation characteristics of whole blood as it responds to varying gravitational (G) forces and flow rates through the channel; (2) the mechanism by which the buffy coat accumulates and is extracted; (3) the efficiency of extraction; (4) those donor and procedural variables that contribute to the final yield; (5) posttransfusion increment response in patients; and (6) the functional integrity of the cells collected.

Human bone marrow processing using a new continuous-flow cell separation device

Transfusion ◽  
2015 ◽  
Vol 56 (4) ◽  
pp. 899-904 ◽  
Author(s):  
Martin G. Guttridge ◽  
Christopher Bailey ◽  
Christopher Sidders ◽  
Jennifer Nichols ◽  
Jane Bromham ◽  
...  
Keyword(s):  
Bone Marrow ◽  
Continuous Flow ◽  
Cell Separation ◽  
Flow Cell ◽  
Human Bone ◽  
Human Bone Marrow ◽  
Separation Device

Principles of Continuous Flow Cell Separation in a Circumferential Flow Disposable Channel

1980 ◽  
pp. 101-113 ◽  
Author(s):  
Jeane P. Hester ◽  
Robert M. Kellogg ◽  
Alfred Mulzet ◽  
Kenneth B. McCredie ◽  
Emil J. Freireich
Keyword(s):  
Continuous Flow ◽  
Cell Separation ◽  
Flow Cell

CELL SEPARATION BY COUNTERCURRENT CENTRIFUGAL ELUTRIATION: RECENT DEVELOPMENTS

2012 ◽  
Vol 42 (3) ◽  
pp. 217-233 ◽  
Author(s):  
Jirka Grosse ◽  
Karl Meier ◽  
Thomas J. Bauer ◽  
Christoph Eilles ◽  
Daniela Grimm
Keyword(s):  
Cell Separation ◽  
Centrifugal Elutriation ◽  
Recent Developments

scholarly journals Principles of blood separation and component extraction in a disposable continuous-flow single-stage channel

Blood ◽  
1979 ◽  
Vol 54 (1) ◽  
pp. 254-268 ◽  
Author(s):  
JP Hester ◽  
RM Kellogg ◽  
AP Mulzet ◽  
VR Kruger ◽  
KB McCredie ◽  
...  
Keyword(s):  
Whole Blood ◽  
Continuous Flow ◽  
Cell Separation ◽  
Flow Cell ◽  
Buffy Coat ◽  
Single Stage ◽  
Flow Rates ◽  
Blood Separation ◽  
Final Yield ◽  
Component Extraction

A single-stage disposable channel and seal that provides for leukocyte and granulocyte collection by continuous-flow cell separation (CFCS) has been designed by the IBM Corporation. This paper describes (1) the separation characteristics of whole blood as it responds to varying gravitational (G) forces and flow rates through the channel; (2) the mechanism by which the buffy coat accumulates and is extracted; (3) the efficiency of extraction; (4) those donor and procedural variables that contribute to the final yield; (5) posttransfusion increment response in patients; and (6) the functional integrity of the cells collected.

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