Abstract
In the modern world, sequencing is an integral part of medicine, biology and other scientific fields. The Illimina / Solexa method is a new generation method and relates to methods of mass parallel sequencing. One of the features of using this method is the sequential pumping of various chemicals through the flow cell in which the reaction occurs. For uniformity and high quality of DNA sequencing, it is necessary that the amount of gas in liquids be minimized. Because many it can adversely affect both during chemical reactions and at the stage of recording reaction results. This article will examine the sequencing system using the Illumina\Solexa method using bubble sensors. An algorithm was developed that periodically receives information from bubble sensors in a microfluidic tube. The information received is processed and allows at certain stages to report deviations from the normal conditions for sequencing. The experimental results are presented.