A Cause of Sensorineural Hearing Loss in Otitis Media with Effusion

1985 ◽  
Vol 12 ◽  
pp. S40-S42 ◽  
Author(s):  
Toshio Yamashita ◽  
Hidehiko Sasa ◽  
Nobuhiro Okazaki ◽  
Tadami Kumazawa
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Otitis Media ◽  
Otitis Media With Effusion ◽  
Sensorineural Hearing

Effects of Platelet Activating Factor on the Tubotympanic Mucosa and Inner Ear in the Guinea Pig

1998 ◽  
Vol 107 (10) ◽  
pp. 876-884 ◽  
Author(s):  
Yoshiharu Ohno ◽  
Yoshihiro Ohashi ◽  
Hideki Okamoto ◽  
Yoshikazu Sugiura ◽  
Yoshiaki Nakai
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Inner Ear ◽  
Otitis Media ◽  
Middle Ear ◽  
Otitis Media With Effusion ◽  
Platelet Activating Factor ◽  
Sensorineural Hearing ◽  
Ciliary Activity ◽  
Middle Ear Mucosa

The effect of platelet activating factor (PAF) was studied to elucidate its role in the pathogenesis of otitis media and sensorineural hearing loss. The PAF alone did not induce a reduction of ciliary activity of the cultured middle ear mucosa. However, a dose-dependent decrease in ciliary activity was observed in the presence of the medium containing both PAF and macrophages. Intravenous injection of PAF did not induce dysfunction of the mucociliary system or morphologic changes of epithelium in the tubotympanum, but cytoplasmic vacuolization and ballooning were observed in the inner ear within 1 hour after injection of PAF. In contrast, intratympanic injection of PAF induced mucociliary dysfunction and some pathologic changes in the tubotympanum. Intratympanic inoculation of PAF induced no pathologic findings in the inner ear. These results suggest that PAF is at least partially involved in the pathogenesis of certain middle ear diseases such as otitis media with effusion. Additionally, PAF might be involved in the pathogenesis of some types of unexplained sensorineural hearing loss.

Sensorineural hearing loss associated with otitis media with effusion in children

1998 ◽  
Vol 46 (3) ◽  
pp. 179-184 ◽  
Author(s):  
Cemil Mutlu ◽  
A.Onur Odabasi ◽  
Kubilay Metin ◽  
Sema Basak ◽  
Gökhan Erpek
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Otitis Media ◽  
Otitis Media With Effusion ◽  
Sensorineural Hearing

Sensorineural Hearing Loss Associated with Otitis media with Effusion

ORL ◽  
1992 ◽  
Vol 54 (2) ◽  
pp. 61-65 ◽  
Author(s):  
Takehiko Harada ◽  
Tatsuya Yamasoba ◽  
Masato Yagi
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Otitis Media ◽  
Otitis Media With Effusion ◽  
Sensorineural Hearing

The effectiveness of glucocorticoid hormones in the treatment of sensorineural disorders

2018 ◽  
pp. 50-57
Author(s):  
Tatyana Kazachonok ◽  
Lyudmila Petrova
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Treatment Outcomes ◽  
Otitis Media ◽  
Treatment Effectiveness ◽  
Otitis Media With Effusion ◽  
Main Group ◽  
Sensorineural Hearing ◽  
Control Group ◽  
Glucocorticoid Hormones

Topicality: Effective treatment of acute sensorineural hearing loss is still relevant due to the fact that the number of diseases accompanied with impaired sound perceptions great, and the treatment outcome is often far from the desire done. Many researchers have noted the positive effect of systemic glucocorticoids in the treatment of acute hearing loss. Adverse effect sin case of long-term systemic use of hormones, such as insomnia, gastric ulcer, impaired glucose tolerance, arterial hypertension, etc., limitations or contraindications to their administration in patients with severe concomitant pathology, the existence of a hemato-perilymphatic barrier, which prevents penetration of glucocorticoids in to the inner environment of the ear, promote the wider use of intratympanic administration of hormones. The purpose of this study was to evaluate treatment effectiveness following intratympanic administration of glucocorticoid hormones in patients with acute sensorineural hearing loss and exudative otitis media. Materials and methods: Analysis was performed to compare treatment outcomes of 92 patients (the main group) with acute sensorineural hearing loss who were administered hormones intratympanically, with the treatment outcomes of 315 patients (the control group) receiving conventional therapy. Treatment outcomes of 23 patients with acute otitis media with effusion accompanied with combined hearing loss with a pronounced sensorineural component were analyzed. Results and discussion: As a result of the treatment, a statistically significant improvement in hearing was obtained in the main group compared to the control group. Of the 23 patients with otitis media with effusion who received the treatment, hearing has restored to the norm in 19 people, and the rest showed an improvement. Thus, intratympanic administration of glucocorticoids increases treatment effectiveness in patients with acute sensorineural hearing loss and helps to restore disturbed sound perception in the treatment of patients with otitis media with effusion.

Otitis Media and Child Development

1979 ◽  
Vol 88 (5_suppl) ◽  
pp. 29-47 ◽  
Author(s):  
Denzil N. Brooks
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Otitis Media ◽  
Otitis Media With Effusion ◽  
Impedance Measurement ◽  
Sensorineural Hearing ◽  
Auditory Dysfunction ◽  
Impedance Testing ◽  
Early Grade ◽  
Mentally Retarded Children

Otitis media with effusion (OME) is the major cause of auditory dysfunction in preschool and early-grade schoolchildren. At especially high risk are children with cleft palate/lip; some groups of mentally retarded children; children from underprivileged communities and children with severe or profound sensorineural hearing loss. In neonates the major concern is to identify those with severe sensorineural hearing loss but awareness of the likelihood of OME is also vital. The hearing loss associated with OME in its early stages may be as small as 10–15 dB and in consequence conventional hearing tests employing pure tones are inadequate as screening procedures. Acoustic impedance testing has proved to be a practicable, acceptable, sensitive and efficient method of identification of OME in infants and children. Impedance measurement cannot, as yet, provide accurate assessment of hearing loss, but this is probably not a serious drawback. The primary requirement is to detect OME in order that swift and effective treatment can be instituted.

scholarly journals Clinicostatistical Study on the Sensorineural Hearing Loss Accompanying Otitis Media with Effusion

1993 ◽  
Vol 1993 (Supplement61) ◽  
pp. 38-41
Author(s):  
Ikuji Kawata ◽  
Etsuo Endo ◽  
Akira Kanamura ◽  
Hirofumi Kihara ◽  
Yoshizumi Wada ◽  
...  
Keyword(s):  
Hearing Loss ◽  
Sensorineural Hearing Loss ◽  
Otitis Media ◽  
Otitis Media With Effusion ◽  
Sensorineural Hearing
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