Simultaneous determination of SU5416 and its phase I and phase II metabolites in rat and dog plasma by LC/MS/MS

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/s0731-7085(01)00341-7 ◽

2001 ◽

Vol 25 (5-6) ◽

pp. 821-832 ◽

Author(s):

Yeping Zhao ◽

Cheng Y Yang ◽

Joshua Haznedar ◽

Lida Antonian

Keyword(s):

Phase I ◽

Simultaneous Determination ◽

Phase Ii ◽

Phase Ii Metabolites

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Simultaneous determination of genistein and its four phase II metabolites in blood by a sensitive and robust UPLC–MS/MS method: Application to an oral bioavailability study of genistein in mice

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2010.03.011 ◽

2010 ◽

Vol 53 (1) ◽

pp. 81-89 ◽

Author(s):

Zhen Yang ◽

Wei Zhu ◽

Song Gao ◽

Haiyan Xu ◽

Baojian Wu ◽

...

Keyword(s):

Simultaneous Determination ◽

Phase Ii ◽

Oral Bioavailability ◽

Bioavailability Study ◽

Phase Ii Metabolites

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Simultaneous enantiomeric determination of MDMA and its phase I and phase II metabolites in urine by liquid chromatography–tandem mass spectrometry with chiral derivatization

Analytical and Bioanalytical Chemistry ◽

10.1007/s00216-012-6385-9 ◽

2012 ◽

Vol 404 (8) ◽

pp. 2427-2435 ◽

Author(s):

Keiko Nakanishi ◽

Munehiro Katagi ◽

Kei Zaitsu ◽

Noriaki Shima ◽

Hiroe Kamata ◽

...

Keyword(s):

Mass Spectrometry ◽

Liquid Chromatography ◽

Tandem Mass Spectrometry ◽

Phase I ◽

Phase Ii ◽

Tandem Mass ◽

Chromatography Tandem Mass Spectrometry ◽

Liquid Chromatography Tandem Mass ◽

Phase Ii Metabolites

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Determination of buprenorphine, naloxone and phase I and phase II metabolites in rat whole blood by LC–MS/MS

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2019.113042 ◽

2020 ◽

Vol 180 ◽

pp. 113042

Author(s):

Camille Cohier ◽

Sophie Salle ◽

Anne Fontova ◽

Bruno Mégarbane ◽

Olivier Roussel

Keyword(s):

Phase I ◽

Phase Ii ◽

Whole Blood ◽

Phase Ii Metabolites

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A newin vitroapproach for the simultaneous determination of phase I and phase II enzymatic activities of human hepatocyte preparations

Rapid Communications in Mass Spectrometry ◽

10.1002/rcm.3359 ◽

2008 ◽

Vol 22 (2) ◽

pp. 240-244 ◽

Author(s):

Agustín Lahoz ◽

Maria Teresa Donato ◽

Sandra Montero ◽

José V. Castell ◽

Maria José Gómez-Lechón

Keyword(s):

Phase I ◽

Simultaneous Determination ◽

Phase Ii ◽

Enzymatic Activities ◽

Human Hepatocyte

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Characterization of phase I and phase II metabolites of hop (Humulus lupulus L.) bitter acids: In vitro and in vivo metabolic profiling by UHPLC-Q-Orbitrap

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2021.114107 ◽

2021 ◽

pp. 114107

Author(s):

Emanuela Salviati ◽

Eduardo Sommella ◽

Albino Carrizzo ◽

Veronica Di Sarno ◽

Alessia Bertamino ◽

...

Keyword(s):

Phase I ◽

Phase Ii ◽

Metabolic Profiling ◽

Humulus Lupulus ◽

Humulus Lupulus L ◽

Bitter Acids ◽

Phase Ii Metabolites

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Metabolism of (2S)-Pterosin A: Identification of the Phase I and Phase II Metabolites in Rat Urine

Drug Metabolism and Disposition ◽

10.1124/dmd.112.045039 ◽

2012 ◽

Vol 40 (8) ◽

pp. 1566-1574 ◽

Author(s):

Yung-Ping Lee ◽

Feng-Lin Hsu ◽

Jaw-Jou Kang ◽

Chien-Kuang Chen ◽

Shoei-Sheng Lee

Keyword(s):

Phase I ◽

Phase Ii ◽

Rat Urine ◽

Phase Ii Metabolites

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High-performance liquid chromatographic method for the simultaneous determination of nalbuphine and its prodrug, sebacoyl dinalbuphine ester, in dog plasma and application to pharmacokinetic studies in dogs

Journal of Chromatography B Biomedical Sciences and Applications ◽

10.1016/s0378-4347(00)00326-1 ◽

2000 ◽

Vol 746 (2) ◽

pp. 241-247 ◽

Author(s):

Li-Heng Pao ◽

Cheng-Huei Hsiong ◽

Oliver Yoa-Pu Hu ◽

Shung-Tai Ho

Keyword(s):

Simultaneous Determination ◽

High Performance ◽

Chromatographic Method ◽

High Performance Liquid Chromatographic ◽

Pharmacokinetic Studies ◽

Liquid Chromatographic Method ◽

Liquid Chromatographic

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Microbial production of phase I and phase II metabolites of midazolam

Xenobiotica ◽

10.3109/00498254.2011.622417 ◽

2011 ◽

Vol 42 (3) ◽

pp. 285-293 ◽

Author(s):

Cyrille Marvalin ◽

Mireille Denoux ◽

Serge Pérard ◽

Sébastien Roy ◽

Robert Azerad

Keyword(s):

Phase I ◽

Phase Ii ◽

Microbial Production ◽

Phase Ii Metabolites

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Simultaneous determination of harmine, harmaline and their metabolites harmol and harmalol in beagle dog plasma by UPLC–ESI-MS/MS and its application to a pharmacokinetic study

Journal of Pharmaceutical and Biomedical Analysis ◽

10.1016/j.jpba.2013.07.019 ◽

2013 ◽

Vol 85 ◽

pp. 162-168 ◽

Author(s):

Lei Zhang ◽

Liang Teng ◽

Can Gong ◽

Wei Liu ◽

Xuemei Cheng ◽

...

Keyword(s):

Simultaneous Determination ◽

Pharmacokinetic Study ◽

Esi Ms ◽

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Quantitative determination of the phase I/phase II ratio in sodium triphosphate by Raman spectrometry

Analytical Chemistry ◽

10.1021/ac60348a022 ◽

1974 ◽

Vol 46 (12) ◽

pp. 1824-1826

Author(s):

Jan. Bus

Keyword(s):

Phase I ◽

Quantitative Determination ◽

Phase Ii ◽

Raman Spectrometry

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