BENDAVIA (MTP-131), A NOVEL MITOCHONDRIA-TARGETING PEPTIDE, IMPROVES ACTIVITY AND EXPRESSION OF CYTOCHROME-C OXIDASE AND ATTENUATES MEDIATORS OF CARDIOMYOCYTE APOPTOSIS IN LEFT VENTRICULAR MYOCARDIUM OF DOGS WITH ADVANCED HEART FAILURE

Hani N. Sabbah; Ramesh C. Gupta; Kristina Szekely; Mengjun Wang; Kefei Zhang; Sharad Rastogi

doi:10.1016/s0735-1097(13)60710-x

BENDAVIA (MTP-131), A NOVEL MITOCHONDRIA-TARGETING PEPTIDE, IMPROVES ACTIVITY AND EXPRESSION OF CYTOCHROME-C OXIDASE AND ATTENUATES MEDIATORS OF CARDIOMYOCYTE APOPTOSIS IN LEFT VENTRICULAR MYOCARDIUM OF DOGS WITH ADVANCED HEART FAILURE

Journal of the American College of Cardiology ◽

10.1016/s0735-1097(13)60710-x ◽

2013 ◽

Vol 61 (10) ◽

pp. E710 ◽

Cited By ~ 1

Author(s):

Hani N. Sabbah ◽

Ramesh C. Gupta ◽

Kristina Szekely ◽

Mengjun Wang ◽

Kefei Zhang ◽

...

Keyword(s):

Heart Failure ◽

Cytochrome C ◽

Cytochrome C Oxidase ◽

Ventricular Myocardium ◽

Left Ventricular ◽

Advanced Heart Failure ◽

Cardiomyocyte Apoptosis ◽

Left Ventricular Myocardium ◽

Targeting Peptide ◽

Mitochondria Targeting

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Long-term therapy with Bendavia (MTP-131), a novel mitochondria-targeting peptide, reverses mitochondrial abnormalities in left ventricular myocardium of dogs with advanced heart failure

European Heart Journal ◽

10.1093/eurheartj/eht307.p640 ◽

2013 ◽

Vol 34 (suppl 1) ◽

pp. P640-P640

Author(s):

H. N. Sabbah ◽

R. C. Gupta ◽

S. Rastogi ◽

M. Wang ◽

K. Zhang

Keyword(s):

Heart Failure ◽

Ventricular Myocardium ◽

Left Ventricular ◽

Advanced Heart Failure ◽

Term Therapy ◽

Left Ventricular Myocardium ◽

Targeting Peptide ◽

Long Term Therapy ◽

Mitochondria Targeting

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BENDAVIA (MTP-131), A NOVEL MITOCHONDRIA-TARGETING PEPTIDE, NORMALIZES EXPRESSION OF CARDIOLIPIN REMODELING GENES AND PROTEINS IN LEFT VENTRICULAR MYOCARDIUM OF DOGS WITH ADVANCED HEART FAILURE

Journal of the American College of Cardiology ◽

10.1016/s0735-1097(14)60758-0 ◽

2014 ◽

Vol 63 (12) ◽

pp. A758 ◽

Cited By ~ 2

Author(s):

Hani N. Sabbah ◽

Ramesh C. Gupta ◽

Sharad Rastogi ◽

Mengjun Wang ◽

Kefei Zhang ◽

...

Keyword(s):

Heart Failure ◽

Ventricular Myocardium ◽

Left Ventricular ◽

Advanced Heart Failure ◽

Left Ventricular Myocardium ◽

Targeting Peptide ◽

Mitochondria Targeting

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BENDAVIA (MTP-131), A NOVEL MITOCHONDRIA-TARGETING PEPTIDE, IMPROVES ACTIVITIES OF MITOCHONDRIA COMPLEX-I AND COMPLEX-IV IN LEFT VENTRICULAR MYOCARDIUM OF DOGS WITH ADVANCED HEART FAILURE

Journal of the American College of Cardiology ◽

10.1016/s0735-1097(14)60882-2 ◽

2014 ◽

Vol 63 (12) ◽

pp. A882

Author(s):

Hani N. Sabbah ◽

Ramesh C. Gupta ◽

Sharad Rastogi ◽

Mengjun Wang ◽

Kefei Zhang ◽

...

Keyword(s):

Heart Failure ◽

Complex I ◽

Ventricular Myocardium ◽

Left Ventricular ◽

Advanced Heart Failure ◽

Left Ventricular Myocardium ◽

Complex Iv ◽

Targeting Peptide ◽

Mitochondria Targeting ◽

Mitochondria Complex I

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LONG-TERM THERAPY WITH BENDAVIA (MTP-131), A NOVEL MITOCHONDRIA-TARGETING PEPTIDE, REVERSES MITOCHONDRIAL FUNCTIONAL ABNORMALITIES IN LEFT VENTRICULAR MYOCARDIUM OF DOGS WITH ADVANCED HEART FAILURE

Journal of the American College of Cardiology ◽

10.1016/s0735-1097(13)60709-3 ◽

2013 ◽

Vol 61 (10) ◽

pp. E709 ◽

Cited By ~ 3

Author(s):

Hani N. Sabbah ◽

Ramesh C. Gupta ◽

Mengjun Wang ◽

Kefei Zhang ◽

Sharad Rastogi

Keyword(s):

Heart Failure ◽

Ventricular Myocardium ◽

Left Ventricular ◽

Advanced Heart Failure ◽

Term Therapy ◽

Left Ventricular Myocardium ◽

Targeting Peptide ◽

Long Term Therapy ◽

Mitochondria Targeting

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Long-term therapy with Bendavia (MTP-131), a novel mitochondria-targeting peptide, normalizes functional mitochondrial abnormalities in left ventricular myocardium of dogs with heart failure

Mitochondrion ◽

10.1016/j.mito.2013.07.039 ◽

2013 ◽

Vol 13 (6) ◽

pp. 912 ◽

Cited By ~ 1

Author(s):

Hani N. Sabbah ◽

Ramesh C. Gupta ◽

Sharad Rastogi ◽

Mengjum Wang ◽

Keife Zhang

Keyword(s):

Heart Failure ◽

Ventricular Myocardium ◽

Left Ventricular ◽

Term Therapy ◽

Left Ventricular Myocardium ◽

Mitochondrial Abnormalities ◽

Targeting Peptide ◽

Long Term Therapy ◽

Mitochondria Targeting

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Long-term therapy with Bendavia (MTP-131), a novel mitochondria-targeting peptide, normalizes Complex-I Activity and reduces the NADH/NAD ratio in left ventricular myocardium of dogs with advanced heart failure

Mitochondrion ◽

10.1016/j.mito.2015.07.064 ◽

2015 ◽

Vol 24 ◽

pp. S21-S22

Author(s):

Hani N. Sabbah ◽

Ramesh C. Gupta

Keyword(s):

Ventricular Myocardium ◽

Left Ventricular ◽

Advanced Heart Failure ◽

Term Therapy ◽

Left Ventricular Myocardium ◽

Targeting Peptide ◽

Long Term Therapy ◽

Complex I Activity ◽

Mitochondria Targeting

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Chronic Therapy With Elamipretide (MTP-131), a Novel Mitochondria-Targeting Peptide, Improves Left Ventricular and Mitochondrial Function in Dogs With Advanced Heart Failure

Circulation Heart Failure ◽

10.1161/circheartfailure.115.002206 ◽

2016 ◽

Vol 9 (2) ◽

Cited By ~ 72

Author(s):

Hani N. Sabbah ◽

Ramesh C. Gupta ◽

Smita Kohli ◽

Mengjun Wang ◽

Souheila Hachem ◽

...

Keyword(s):

Heart Failure ◽

Mitochondrial Function ◽

Left Ventricular ◽

Advanced Heart Failure ◽

Chronic Therapy ◽

Targeting Peptide ◽

Mitochondria Targeting

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Thymosin β4 and Its Cleavage Product Ac-SDKP Are Down-Regulated in Left Ventricular Myocardium of Patients With Advanced Heart Failure

The Journal of Heart and Lung Transplantation ◽

10.1016/j.healun.2015.01.238 ◽

2015 ◽

Vol 34 (4) ◽

pp. S89 ◽

Cited By ~ 1

Author(s):

H.N. Sabbah ◽

R.C. Gupta ◽

V. Singh-Gupta

Keyword(s):

Heart Failure ◽

Ventricular Myocardium ◽

Left Ventricular ◽

Advanced Heart Failure ◽

Cleavage Product ◽

Left Ventricular Myocardium ◽

Thymosin Β4

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Activity of Cytochrome c Oxidase in the Right and Left Ventricular Myocardium of Male and Female Rats Exposed To Intermittent High Altitude Hypoxiaa

Annals of the New York Academy of Sciences ◽

10.1111/j.1749-6632.1999.tb09242.x ◽

1999 ◽

Vol 874 (1 HEART IN STRE) ◽

pp. 269-277 ◽

Cited By ~ 7

Author(s):

A. STIEGLEROVA ◽

Z. DRAHOTA ◽

J. HOUSTEK ◽

M. MILEROVA ◽

V. PELOUCH ◽

...

Keyword(s):

Cytochrome C ◽

High Altitude ◽

Cytochrome C Oxidase ◽

Ventricular Myocardium ◽

Left Ventricular ◽

Female Rats ◽

Left Ventricular Myocardium ◽

Male And Female ◽

Male And Female Rats ◽

The Right

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P6170Elamipretide normalizes protein and mRNA expression levels of mitofilin in left ventricular myocardium of dogs with advanced heart failure

European Heart Journal ◽

10.1093/eurheartj/ehx493.p6170 ◽

2017 ◽

Vol 38 (suppl_1) ◽

Author(s):

H.N. Sabbah ◽

R.C. Gupta ◽

V. Singh-Gupta ◽

K. Zhang ◽

J. Xu

Keyword(s):

Heart Failure ◽

Mrna Expression ◽

Ventricular Myocardium ◽

Left Ventricular ◽

Advanced Heart Failure ◽

Left Ventricular Myocardium ◽

Expression Levels ◽

Mrna Expression Levels

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