scholarly journals TRANSFER OF CARE LEADING TO TOTAL ARTIFICIAL HEART AS BRIDGE TO TRANSPLANT IN END STAGE CARDIAC AMYLOIDOSIS

2015 ◽  
Vol 65 (10) ◽  
pp. A612
Author(s):  
Michael Scully ◽  
Gregory Francisco ◽  
Keshav Nayak
Keyword(s):  
Artificial Heart ◽  
Cardiac Amyloidosis ◽  
Total Artificial Heart ◽  
Transfer Of Care ◽  
Bridge To Transplant ◽  
End Stage

scholarly journals Success of Thrombectomy in Management of Ischemic Stroke in Two Patients with SynCardia Total Artificial Heart in Bridge-to-Transplantation

2021 ◽  
Vol 8 (9) ◽  
pp. 126
Author(s):  
Brendan Le Picault ◽  
Charles-Henri David ◽  
Pierre-Louis Alexandre ◽  
Cédric Lenoble ◽  
Philippe Bizouarn ◽  
...  
Keyword(s):  
Ischemic Stroke ◽  
Case Report ◽  
Artificial Heart ◽  
Mechanical Thrombectomy ◽  
Total Artificial Heart ◽  
Neurological Deficits ◽  
Circulatory Support ◽  
Hemorrhagic Complication ◽  
Bridge To Transplant ◽  
End Stage

Introduction: Circulatory assistance from a SynCardia Total Artificial Heart (SynCardia-TAH) is a reliable bridge-to-transplant solution for patients with end-stage biventricular heart failure. Ischemic strokes affect about 10% of patients with a SynCardia-TAH. We report for the first time in the literature two successful thrombectomies to treat the acute phase of ischemic stroke in two patients treated with a SynCardia-TAH in the bridge-to-transplant (BTT). Case report: We follow two patients with circulatory support from a SynCardia-TAH in the bridge-to-transplant for terminal biventricular cardiac failure with ischemic stroke during the support period. An early in-hospital diagnosis enables the completion of a mechanical thrombectomy within the first 6 h of the onset of symptoms. There was no intracranial hemorrhagic complication during or after the procedure and the patients fully recovered from neurological deficits, allowing a successful heart transplant. Conclusion: This case report describes the possibility of treating ischemic strokes under a SynCardia-TAH by mechanical thrombectomy following the same recommendations as for the general population with excellent results and without any hemorrhagic complication during or after the procedure.

scholarly journals Loeffler's Endocarditis Treated with Total Artificial Heart as Bridge to Transplant

2021 ◽  
Vol 40 (4) ◽  
pp. S528
Author(s):  
G.T. Gibson ◽  
S. Rangasamy ◽  
J. Contreras ◽  
A. Singhvi ◽  
A. Fox ◽  
...  
Keyword(s):  
Artificial Heart ◽  
Total Artificial Heart ◽  
Bridge To Transplant

305 Bridge to Transplant Using BiVAD or Total Artificial Heart: Is There a Survival Difference?

2012 ◽  
Vol 31 (4) ◽  
pp. S109-S110
Author(s):  
A. Nguyen ◽  
M. Pozzi ◽  
C. Mastroianni ◽  
P. Leprince ◽  
P. Alain ◽  
...  
Keyword(s):  
Artificial Heart ◽  
Total Artificial Heart ◽  
Bridge To Transplant ◽  
Survival Difference

Current state of total artificial heart therapy and introduction of the most important total artificial heart systems

2019 ◽  
Vol 64 (3) ◽  
pp. 247-250
Author(s):  
Sotirios Spiliopoulos ◽  
Vera Hergesell ◽  
Andrae Wasler ◽  
Otto Dapunt
Keyword(s):  
Heart Failure ◽  
Organ Donation ◽  
Clinical Outcomes ◽  
Artificial Heart ◽  
Cardiac Transplantation ◽  
Total Artificial Heart ◽  
Successful Implementation ◽  
Technical Requirements ◽  
Current State ◽  
End Stage

AbstractDue to the declining instances of organ donation, total artificial heart (TAH) therapy is of increasing importance for the management of end-stage biventricular heart failure. We introduce the currently most important established and novel TAH systems (SynCardia, CARMAT, ReinHeart, BiVACOR), report clinical outcomes and discuss technical requirements for the successful implementation of TAH therapy as an alternative to cardiac transplantation.

The Total Artificial Heart

1991 ◽  
Vol 2 (3) ◽  
pp. 587-597
Author(s):  
Lawrence E. Barker
Keyword(s):  
Artificial Heart ◽  
Total Artificial Heart ◽  
Thromboembolic Events ◽  
Bridge To Transplant ◽  
University Of Utah ◽  
Cardiac Assistance ◽  
Permanent Implants ◽  
Mechanical Devices ◽  
The University

In the early 1800s, an awareness of potential ventricular failure stimulated interest in artificial heart replacement. In 1937 the first total artificial heart (TAH) was implanted into the chest of a dog by Russian physicians. The primary driving force for mechanical cardiac assistance developed from the necessity for circulatory assistance in order to perform corrective cardiac surgery. In 1953 the first successful closure of an atrial septal defect using extracorporeal circulation was performed. During the following decade the concept of using mechanical devices to assist the failing heart was aggressively pursued. This culminated in the first implant of a TAH in a human in 1969 as a bridge to transplant. Clinical implant of the TAH as a permanent device was performed in 1982 by researchers at the University of Utah. This patient lived for 112 days. Three successive permanent implants were performed in Louisville, Kentucky, with one patient surviving for 620 days. All of these permanent TAH patients suffered from device-related complications including bleeding, infection, and thromboembolic events. It became apparent that the present configuration of the TAH with its external drive lines and large air console was not ideal for long-term support. In 1985 the first implant of the Symbion J-7-100 TAH (Jarvik-7) as a bridge to transplant was performed. This patient was supported by the device for 9 days and was successfully transplanted and discharged home. Since 1985 more than 170 patients have been bridged using the Symbion J-7 TAH with more than 70% of these patients being successfully transplanted. The incidence of thromboembolic events has dramatically reduced with better understanding of anticoagulation requirements. Infection continues to be the greatest potential complication with these patients. In spite of this, the pneumatic TAH has proved to be an adequate bridge to transplant device

Reintroduction of the Jarvik/CardioWest Total Artificial Heart as a Bridge to Transplant

1998 ◽  
pp. 421-423
Author(s):  
Ricardo J. Moreno-Cabral ◽  
Robert M. Adamson ◽  
Walter P. Dembitsky ◽  
Pat O. Daily ◽  
Francisco A. Arabía ◽  
...  
Keyword(s):  
Artificial Heart ◽  
Total Artificial Heart ◽  
Bridge To Transplant

The Biocompatibility Challenges in the Total Artificial Heart Evolution

2019 ◽  
Vol 21 (1) ◽  
pp. 85-110 ◽  
Author(s):  
Eleonora Dal Sasso ◽  
Andrea Bagno ◽  
Silvia T.G. Scuri ◽  
Gino Gerosa ◽  
Laura Iop
Keyword(s):  
Heart Failure ◽  
Artificial Heart ◽  
Comprehensive Analysis ◽  
Therapeutic Options ◽  
Total Artificial Heart ◽  
Final Treatment ◽  
End Stage Heart Failure ◽  
End Stage

There are limited therapeutic options for final treatment of end-stage heart failure. Among them, implantation of a total artificial heart (TAH) is an acceptable strategy when suitable donors are not available. TAH development began in the 1930s, followed by a dramatic evolution of the actuation mechanisms operating the mechanical pumps. Nevertheless, the performance of TAHs has not yet been optimized, mainly because of the low biocompatibility of the blood-contacting surfaces. Low hemocompatibility, calcification, and sensitivity to infections seriously affect the success of TAHs. These unsolved issues have led to the withdrawal of many prototypes during preclinical phases of testing. This review offers a comprehensive analysis of the pathophysiological events that may occur in the materials that compose TAHs developed to date. In addition, this review illustrates bioengineering strategies to prevent these events and describes the most significant steps toward the achievement of a fully biocompatible TAH.

scholarly journals Paving the way for destination therapy of end-stage biventricular heart failure: the ReinHeart total artificial heart concept

2014 ◽  
Vol 46 (6) ◽  
pp. 935-936 ◽  
Author(s):  
R. Koerfer ◽  
S. Spiliopoulos ◽  
T. Finocchiaro ◽  
D. Guersoy ◽  
G. Tenderich ◽  
...  
Keyword(s):  
Heart Failure ◽  
Artificial Heart ◽  
Total Artificial Heart ◽  
Destination Therapy ◽  
End Stage ◽  
The Way
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