scholarly journals THE APTAMER BC 007 FOR THE TREATMENT OF DILATED CARDIOMYOPATHIES WITH POSITIVITY FOR ANTI-β1-ADRENOCEPTOR AUTOANTIBODIES: DATA FROM STUDIES IN DOBERMAN PINSCHERS AND HUMANS

2020 ◽  
Vol 75 (11) ◽  
pp. 3623
Author(s):  
Ingolf Schimke ◽  
Niels Becker ◽  
Gerd Wallukat ◽  
Katrin Wenzel ◽  
Annekathrin Haberland ◽  
...  
Keyword(s):  
2012 ◽  
Vol 27 (1) ◽  
pp. 106-111 ◽  
Author(s):  
K. Foss ◽  
R.C. da Costa ◽  
P.J. Rajala-Shultz ◽  
M.J. Allen

1975 ◽  
Vol 16 (1-12) ◽  
pp. 11-19 ◽  
Author(s):  
A. D. J. WATSON ◽  
C. R. R. HUXTABLE ◽  
B. R. H. FARROW
Keyword(s):  

2017 ◽  
Vol 30 (2) ◽  
pp. 310-314 ◽  
Author(s):  
Julian A. Crespi ◽  
Laura S. Barrientos ◽  
Guillermo Giovambattista

von Willebrand disease (vWD) is the most common inherited coagulopathy in dogs, particularly in Doberman Pinschers. We developed a pyrosequencing-based assay to estimate the frequency of the c.7437G>A mutation associated with vWD type 1 in the Doberman Pinscher population of Buenos Aires, Argentina. We found a 0.41 frequency for the mutated allele, which varied significantly within families (family 1 = 0.43, family 2 = 0.58, unrelated animals = 0.35). The use of a popular founder male carrier of mutant allele A increased vWD incidence within a family and in the general population. The mode of inheritance was confirmed as autosomal dominant with incomplete penetrance. No differences were found between sexes and coat colors. Pyrosequencing was a good complement to clinical and coagulation tests for vWD type 1 diagnosis and a useful alternative for detecting the c.7437G>A mutation.


2020 ◽  
Vol 257 (10) ◽  
pp. 1041-1044 ◽  
Author(s):  
Kathryn M. Meurs ◽  
Joshua A. Stern ◽  
Darcy Adin ◽  
Bruce W. Keene ◽  
Theresa C. De Francesco ◽  
...  

2004 ◽  
Vol 18 (5) ◽  
pp. 647-650 ◽  
Author(s):  
P.J.J. Mandigers ◽  
T.S.G.A.M. Ingh ◽  
P. Bode ◽  
E. Teske ◽  
J. Rothuizen

Sign in / Sign up

Export Citation Format

Share Document