scholarly journals SALVAGE CATHETER-DIRECTED THROMBOLYSIS FOR MASSIVE PULMONARY EMBOLISM CAUSED BY DISLODGED THROMBUS DURING THROMBECTOMY ATTEMPT FOR PHLEGMASIA CERULEA DOLENS

2021 ◽  
Vol 77 (18) ◽  
pp. 2926
Author(s):  
Ilhwan Yeo ◽  
Minar Chhetry ◽  
Xuming Dai
VASA ◽  
2020 ◽  
Vol 49 (4) ◽  
pp. 333-337 ◽  
Author(s):  
Francisco Leonardo Galastri ◽  
Leonardo Guedes Moreira Valle ◽  
Breno Boueri Affonso ◽  
Marcela Juliano Silva ◽  
Rodrigo Gobbo Garcia ◽  
...  

Summary: COVID-19 is a recently identified illness that is associated with thromboembolic events. We report a case of pulmonary embolism in a patient with COVID-19, treated by catheter directed thrombectomy. A 57 year old patient presented to the emergency center with severe COVID-19 symptoms and developed massive pulmonary embolism. The patient was treated with catheter directed thrombolysis (CDT) and recovered completely. Coagulopathy associated with COVID-19 is present in all severe cases and is a dynamic process. We describe a case of massive/high risk pulmonary embolism, in a patient with COVID-19 receiving full anticoagulation, who was treated by percutaneous intervention. CDT can be an additional therapeutic option in patients with COVID-19 and pulmonary embolism that present with rapid clinical collapse.


2017 ◽  
Vol 23 (1) ◽  
pp. 65-71 ◽  
Author(s):  
Akhilesh K Sista ◽  
Oren A Friedman ◽  
Eda Dou ◽  
Brendan Denvir ◽  
Gulce Askin ◽  
...  

Pulmonary Embolism Response Teams (PERTs) have emerged to provide rapid multidisciplinary assessment and treatment of PE patients. However, descriptive institutional experience and preliminary outcomes data from such teams are sparse. PERT activations were identified through a retrospective review. Only confirmed submassive or massive PEs were included in the data analysis. In addition to baseline variables, the therapeutic intervention, length of stay (LOS), in-hospital mortality, and bleeding rate/severity were recorded. A total of 124 PERT activations occurred over 20 months: 43 in the first 10 months and 81 in the next 10. A total of 87 submassive (90.8%) and massive (9.2%) PE patients were included. The median age was 65 (51–75 IQR) years. Catheter-directed thrombolysis (CDT) was administered to 25 patients, systemic thrombolysis (ST) to six, and anticoagulation alone (AC) to 54. The median ICU stay and overall LOS were 6 (3–10 IQR) and 7 (4–14 IQR) days, respectively, with no association with any variables except a brain natriuretic peptide (BNP) >100 pg/mL ( p=0.008 ICU LOS; p=0.047 overall LOS). Twelve patients (13.7%) died in the hospital, nine of whom had metastatic or brain cancer, with a median overall LOS of 13 (11–17 IQR) days. There were five major bleeds: one in the CDT group, one in the ST group, and three in the AC group. Overall, (1) PERT activations increased after the first 10 months; (2) BNP >100 pg/mL was associated with a longer LOS; (3) rates of mortality and bleeding did not correlate with treatment; and (4) the majority of in-hospital deaths occurred in patients with advanced cancer.


2015 ◽  
Vol 39 (1) ◽  
pp. 140-143 ◽  
Author(s):  
Kyungmouk S. Lee ◽  
Akhilesh K. Sista ◽  
Oren A. Friedman ◽  
James M. Horowitz ◽  
Jeffrey L. Port ◽  
...  

2018 ◽  
Vol 45 (3) ◽  
pp. 182-185 ◽  
Author(s):  
Mohamed Shokr ◽  
Ahmed Rashed ◽  
Ashraf Mostafa ◽  
Tamam Mohamad ◽  
Theodore Schreiber ◽  
...  

Right ventricular failure secondary to pulmonary embolism is associated with morbidity and death. The Impella RP System has often been used for percutaneous mechanical circulatory support in patients with right ventricular failure from other causes, including myocardial infarction, cardiac surgery, and left ventricular assist device implantation. We report 2 cases of massive pulmonary embolism in which combined Impella RP use and ultrasound-assisted catheter-directed thrombolysis effectively treated shock caused by right ventricular failure and contributed to successful outcomes. To our knowledge, only one other patient with this indication had been treated with the Impella RP device.


Perfusion ◽  
2017 ◽  
Vol 33 (4) ◽  
pp. 323-325 ◽  
Author(s):  
Aditya Badheka ◽  
Pradeep Bangalore Prakash ◽  
Veerajalandhar Allareddy

Background: Acute massive pulmonary embolism (PE) is a very rare condition in children. We report the successful use of veno-arterial extracorporeal membrane oxygenation (VA ECMO) as a lifesaving modality in a child with acute massive PE. Case presentation: A nine-year-old female with spinal muscular atrophy type 1, chronic respiratory failure with tracheostomy and ventilator dependence presented with tachypnea and hypoxia. She had recent coiling of her pulmonary arterio-venous malformation. A chest computerized tomography scan showed massive bilateral PE. Urgent catheter-directed thrombolysis failed. She was placed on VA-ECMO with stabilization of hemodynamics. She underwent surgical thrombo-embolectomy followed by weaning of ECMO support. Discussion: The use of VA ECMO supported the cardio-respiratory status and perfusion to facilitate surgical embolectomy.


2018 ◽  
Vol 02 (01) ◽  
pp. 017-022
Author(s):  
Elie Portnoy ◽  
Vibhor Wadhwa ◽  
Mariana Barbosa ◽  
Clifford Weiss ◽  
Brian Holly ◽  
...  

AbstractThe authors seek to evaluate hemodynamic parameters as potential clinical markers of real-time clinical improvement among patients with massive pulmonary embolism (PE) in correlation with post-thrombolytic pulmonary arterial pressure improvement and overall clinical outcome. Thirteen patients with submassive or massive PE were admitted to the interventional radiology service and treated with catheter-directed thrombolysis. Among the four patients who qualified as massive PE, systolic blood pressure (BP) and vasopressor dependence suggested meaningful trends toward clinical improvement, after only 26.4% of treatment course/dose. Hemodynamic parameters such as systolic BP and inotropic vasopressor dependence may be considered in future treatment protocols as early indicators of treatment response.


2019 ◽  
Vol 73 (9) ◽  
pp. 2176
Author(s):  
José Gildardo Paredes-Vázquez ◽  
Carlos Sanchez-Diaz ◽  
Felipe Valdes ◽  
Luis Manautou ◽  
Vicente Jimenez Franco ◽  
...  

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