scholarly journals A neuroendocrine model of obesity worsen insulin resistance of spontaneously hypertensive rats: a new model of type 2 diabetes

2003 ◽  
Vol 16 (5) ◽  
pp. A19
Author(s):  
C FERREIRA
Keyword(s):  
Insulin Resistance ◽  
Type 2 Diabetes ◽  
Spontaneously Hypertensive Rats ◽  
Hypertensive Rats ◽  
Spontaneously Hypertensive ◽  
New Model

Protective effects of losartan on some type 2 diabetes mellitus-induced complications in Wistar and spontaneously hypertensive rats

2020 ◽  
Vol 35 (3) ◽  
pp. 527-538
Author(s):  
Daniela Pechlivanova ◽  
Ekaterina Krumova ◽  
Nedelina Kostadinova ◽  
Jeny Mitreva-Staleva ◽  
Petar Grozdanov ◽  
...  
Keyword(s):  
Diabetes Mellitus ◽  
Type 2 Diabetes ◽  
Type 2 Diabetes Mellitus ◽  
Spontaneously Hypertensive Rats ◽  
Protective Effects ◽  
Hypertensive Rats ◽  
Spontaneously Hypertensive

β-Pro7Ang III is a novel highly selective angiotensin II type 2 receptor (AT2R) agonist, which acts as a vasodepressor agent via the AT2R in conscious spontaneously hypertensive rats

2015 ◽  
Vol 129 (6) ◽  
pp. 505-513 ◽  
Author(s):  
Mark Del Borgo ◽  
Yan Wang ◽  
Sanja Bosnyak ◽  
Morimer Khan ◽  
Pia Walters ◽  
...  
Keyword(s):  
Cardiovascular Disease ◽  
Angiotensin Ii ◽  
Protein Binding ◽  
Binding Site ◽  
Spontaneously Hypertensive Rats ◽  
Protective Effects ◽  
Ang Ii ◽  
Hypertensive Rats ◽  
Spontaneously Hypertensive

We have synthesized a highly selective compound that is able to target a protein-binding site [called angiotensin (Ang) II type 2 receptor, AT2R] in the cardiovascular system. This research tool will enhance our ability to stimulate AT2R to produce protective effects against cardiovascular disease.

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