P.2.b.018 Impaired cognitive inhibition and verbal memory in association with the STin2 polymorphism of the serotonin transporter gene in major depression

2006 ◽  
Vol 16 ◽  
pp. S311
Author(s):  
A. Sárosi ◽  
G.K. Balogh ◽  
E. Dömötör ◽  
M. Sasvári-Székely ◽  
A. Székely ◽  
...  
Keyword(s):  
Major Depression ◽  
Serotonin Transporter ◽  
Verbal Memory ◽  
Serotonin Transporter Gene ◽  
Cognitive Inhibition ◽  
Transporter Gene

Neuroticism Mediates the Association of the Serotonin Transporter Gene with Lifetime Major Depression

2006 ◽  
Vol 53 (1) ◽  
pp. 1-8 ◽  
Author(s):  
Marcus R. Munafò ◽  
Taane G. Clark ◽  
Kate H. Roberts ◽  
Elaine C. Johnstone
Keyword(s):  
Major Depression ◽  
Serotonin Transporter ◽  
Serotonin Transporter Gene ◽  
Transporter Gene

scholarly journals Association of Serotonin Transporter Gene AluJb Methylation with Major Depression, Amygdala Responsiveness, 5-HTTLPR/rs25531 Polymorphism, and Stress

2017 ◽  
Vol 43 (6) ◽  
pp. 1308-1316 ◽  
Author(s):  
Ilona Schneider ◽  
Harald Kugel ◽  
Ronny Redlich ◽  
Dominik Grotegerd ◽  
Christian Bürger ◽  
...  
Keyword(s):  
Major Depression ◽  
Serotonin Transporter ◽  
Serotonin Transporter Gene ◽  
Transporter Gene

Serotonin Transporter Gene Polymorphisms and Sertraline Response in Major Depression Patients

2008 ◽  
Vol 12 (2) ◽  
pp. 225-231 ◽  
Author(s):  
Ozlem Dogan ◽  
Nevzat Yuksel ◽  
Mehmet Ali Ergun ◽  
Akin Yilmaz ◽  
Mustafa N. Ilhan ◽  
...  
Keyword(s):  
Major Depression ◽  
Serotonin Transporter ◽  
Gene Polymorphisms ◽  
Serotonin Transporter Gene ◽  
Transporter Gene

Serotonin transporter gene status predicts caudate nucleus but not amygdala or hippocampal volumes in older persons with major depression

2007 ◽  
Vol 98 (1-2) ◽  
pp. 137-142 ◽  
Author(s):  
Ian B. Hickie ◽  
Sharon L. Naismith ◽  
Philip B. Ward ◽  
Elizabeth M. Scott ◽  
Philip B. Mitchell ◽  
...  
Keyword(s):  
Major Depression ◽  
Caudate Nucleus ◽  
Serotonin Transporter ◽  
Older Persons ◽  
Serotonin Transporter Gene ◽  
Transporter Gene ◽  
Gene Status

scholarly journals Mood changes after delivery: role of the serotonin transporter gene

2008 ◽  
Vol 193 (5) ◽  
pp. 383-388 ◽  
Author(s):  
J. Sanjuan ◽  
R. Martin-Santos ◽  
L. Garcia-Esteve ◽  
J. M. Carot ◽  
R. Guillamat ◽  
...  
Keyword(s):  
Depressive Symptoms ◽  
Major Depression ◽  
Serotonin Transporter ◽  
Post Partum ◽  
Serotonin Transporter Gene ◽  
High Expression ◽  
Transporter Gene ◽  
Mood Changes ◽  
Post Partum Period

BackgroundPolymorphic variations in the serotonin transporter gene (5-HTT) moderate the depressogenic effects of tryptophan depletion. After childbirth there is a sharp reduction in brain tryptophan availability, thus polymorphic variations in5-HTTmay play a similar role in the post-partum period.AimsTo study the role of5-HTTpolymorphic variations in mood changes after delivery.MethodOne thousand, eight hundred and four depression-free Spanish women were studied post-partum. We evaluated depressive symptoms at 2–3 days, 8 weeks and 32 weeks post-partum. We used diagnostic interview to confirm major depression for all probable cases. Based on two polymorphisms of5-HTT(5-HTTLPR and STin2 VNTR), three genotype combinations were created to reflect different levels of5-HTTexpression.ResultsOne hundred and seventy-three women (12.7%) experienced major depression during the 32-week post-partum period. Depressive symptoms were associated with the high-expression5-HTTgenotypes in a dose–response fashion at 8 weeks post-partum, but not at 32 weeks.ConclusionsHigh-expression5-HTTgenotypes may render women more vulnerable to depressive symptoms after childbirth.

scholarly journals Childhood Stress, Serotonin Transporter Gene and Brain Structures in Major Depression

2010 ◽  
Vol 35 (6) ◽  
pp. 1383-1390 ◽  
Author(s):  
Thomas Frodl ◽  
Elena Reinhold ◽  
Nikolaos Koutsouleris ◽  
Gary Donohoe ◽  
Brigitta Bondy ◽  
...  
Keyword(s):  
Major Depression ◽  
Serotonin Transporter ◽  
Brain Structures ◽  
Serotonin Transporter Gene ◽  
Transporter Gene ◽  
Childhood Stress
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