Drug diffusion and binding in ionizable interpenetrating networks from poly(vinyl alcohol) and poly(acrylic acid)

1998 ◽  
Vol 46 (1) ◽  
pp. 15-29 ◽  
Author(s):  
Nicholas A. Peppas ◽  
Shelia L. Wright
Keyword(s):  
Acrylic Acid ◽  
Vinyl Alcohol ◽  
Poly Vinyl Alcohol ◽  
Interpenetrating Networks ◽  
Drug Diffusion ◽  
Poly Acrylic Acid

Bending Characteristics of Electrical Responsive Poly(vinyl alcohol)/Poly(acrylic acid) Semi-Interpenetrating Polymer Network Hydrogel under DC Electric Field

2009 ◽  
Vol 79-82 ◽  
pp. 1595-1598 ◽  
Author(s):  
Wei Wei Cui ◽  
Li Zhu Liu ◽  
Xing Song Zhu
Keyword(s):  
Acrylic Acid ◽  
Osmotic Pressure ◽  
Vinyl Alcohol ◽  
Polymer Network ◽  
Interpenetrating Polymer Network ◽  
Poly Vinyl Alcohol ◽  
Gradient Theory ◽  
Stimuli Responsive ◽  
Interpenetrating Networks ◽  
Poly Acrylic Acid

Semi-Interpenetrating networks (SIPN) hydrogel composed of poly (acrylic acid) (PAA) and poly (vinyl alcohol) (PVA) was prepared by free radical solution polymerization. The SIPN was characterized by Fourier transform infrared spectroscopy (FTIR). The electric stimuli responsive characteristics were investigated. The hydrogel bent toward the anode initially, altered the bending direction for two times and bent toward the anode ultimately when it was placed in a 0.1 M NaCl aqueous solution under non-contact DC field. For interpreting the special deformation the osmotic pressure curves according to Shiga’ osmotic pressure model were simulated and the pH gradient theory was applied to explain the final direction.

Synthesis, characterization, and their some chemical and biological properties of PVA/PAA/nPS hydrogel nanocomposites: Hydrogel and wound dressing

2020 ◽  
Vol 35 (3) ◽  
pp. 203-215
Author(s):  
Mehmet Emin Diken ◽  
Berna Koçer Kizilduman ◽  
Begümhan Yilmaz Kardaş ◽  
Enes Emre Doğan ◽  
Mehmet Doğan ◽  
...  
Keyword(s):  
Fourier Transform ◽  
Acrylic Acid ◽  
Infrared Spectra ◽  
Vinyl Alcohol ◽  
Fourier Transform Infrared ◽  
Poly Vinyl Alcohol ◽  
Seed Particles ◽  
Fourier Transform Infrared Spectra ◽  
Hydrogel Nanocomposites ◽  
Poly Acrylic Acid

The nanocomposite hydrogels were prepared by dispersing of the nanopomegranate seed particles into poly(vinyl alcohol)/poly(acrylic acid) blend matrix in an aqueous medium by the solvent casting method. These hydrogels were characterized using scanning electron microscopy, Fourier transform infrared spectra, differential scanning calorimetry, and optical contact angle instruments. The nanopomegranate seed, blend, and hydrogel nanocomposites were tested for microbial activity. In addition, cytocompatibilities of these blend and hydrogel nanocomposites/composites were tested on human lymphocyte with in vitro MTS cell viability assays. Fourier transform infrared spectra revealed that esterification reaction took place among functional groups in the structure of poly(vinyl alcohol) and poly(acrylic acid). The hydrophilic properties of all hydrogels decreased with increasing nanopomegranate seed content. The mean diameters of the nanopomegranate seed particles were about 88 nm. Nanopomegranate seed particles demonstrated antibacterial properties against gram-positive bacteria, Staphylococcus aureus, and gram-negative bacteria, Escherichia coli. The lymphocyte viabilities increased after addition of nanopomegranate seeds into the polymer blend. The swelling behavior of blend and hydrogels was dependent on the cross-linking density created by the reaction between poly(vinyl alcohol)/poly(acrylic acid) blend and nanopomegranate seed. Scanning electron microscopy images were highly consistent with Fourier transform infrared spectra, differential scanning calorimetry, and antibacterial activity results.

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