156 Comparison Between Screen-detected Invasive Breast Cancer and Symptomatic Breast Cancer According to Immunohistochemical Intrinsic Subtypes

2012 ◽  
Vol 48 ◽  
pp. S85
Author(s):  
N. Kobayashi ◽  
K. Ushimado ◽  
M. Hikichi ◽  
S. Miyajima ◽  
T. Utsumi
Keyword(s):  
Breast Cancer ◽  
Invasive Breast Cancer ◽  
Intrinsic Subtypes ◽  
Symptomatic Breast Cancer ◽  
Symptomatic Breast

scholarly journals The value of mammography in women with focal breast complaints in addition to initial targeted ultrasound

2020 ◽  
Author(s):  
L. Appelman ◽  
P. T. M. Appelman ◽  
C. C. N. Siebers ◽  
P. Bult ◽  
H. L. S. Go ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Breast Imaging ◽  
Digital Breast Tomosynthesis ◽  
Breast Disease ◽  
Added Value ◽  
Breast Tomosynthesis ◽  
Targeted Ultrasound ◽  
Symptomatic Breast Cancer ◽  
Symptomatic Breast

Abstract Purpose To determine the added value of mammography in women with focal breast complaints and the utility of initial targeted ultrasound in this setting. Methods Women with symptomatic breast disease who were evaluated by breast imaging (mammography/digital breast tomosynthesis and ultrasound) between January 2016 and December 2016 in the Radboud University Medical Centre were included. We retrospectively collected the following data: date of birth, indication of imaging, visibility on mammography/ultrasound, whether biopsy was taken, additional findings, BI-RADS-classification, pathology and follow-up results. Results A total of 494 women were included (mean age 46.5, range 30 to 93). In 49 women (9.9%), symptomatic breast cancer was diagnosed, all visible during targeted ultrasound. The negative predictive value of targeted ultrasound was very high (99.8%). Additional findings on mammography were significantly more often malignant when the symptomatic lesion was also malignant (3.8% vs 70%, P < 0.05). In only one patient with symptoms caused by a benign finding, an incidental malignancy was detected on mammography outside the area of complaint (detection rate 2.2/1000 examinations). Conclusions The contribution of mammography for cancer detection in women with focal breast complaints is very low when targeted ultrasound is performed. Additional findings are most common in patients with symptomatic breast cancer. Our results suggest that initial targeted ultrasound is a more appropriate initial tool for the evaluation of focal breast complaints. Mammography could be performed on indication only.

scholarly journals Population estimates of survival in women with screen-detected and symptomatic breast cancer taking account of lead time and length bias

2008 ◽  
Vol 116 (1) ◽  
pp. 179-185 ◽  
Author(s):  
Gill Lawrence ◽  
Matthew Wallis ◽  
Prue Allgood ◽  
Iris D. Nagtegaal ◽  
Jane Warwick ◽  
...  
Keyword(s):  
Breast Cancer ◽  
Lead Time ◽  
Population Estimates ◽  
Length Bias ◽  
Symptomatic Breast Cancer ◽  
Symptomatic Breast
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