420: Functional role of the long noncoding RNA ANRIL in silencing of the INK4/ARF tumor suppressor locus in urothelial carcinoma

2014 ◽  
Vol 50 ◽  
pp. S100-S101
Author(s):  
M. Hoffmann ◽  
G. Niegisch ◽  
W. Schulz
Keyword(s):  
Tumor Suppressor ◽  
Urothelial Carcinoma ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Functional Role

Expression and Functional Role of Reprogramming-Related Long Noncoding RNA (lincRNA-ROR) in Glioma

2015 ◽  
Vol 56 (3) ◽  
pp. 623-630 ◽  
Author(s):  
Shiyu Feng ◽  
Jie Yao ◽  
Yang Chen ◽  
Peiliang Geng ◽  
Haibo Zhang ◽  
...  
Keyword(s):  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Functional Role

scholarly journals Signaling Events Downstream of AHR Activation That Contribute to Toxic Responses: The Functional Role of an AHR-Dependent Long Noncoding RNA ( slincR ) Using the Zebrafish Model

2018 ◽  
Vol 126 (11) ◽  
pp. 117002 ◽  
Author(s):  
Gloria R. Garcia ◽  
Prarthana Shankar ◽  
Cheryl L. Dunham ◽  
Abraham Garcia ◽  
Jane K. La Du ◽  
...  
Keyword(s):  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Functional Role ◽  
Zebrafish Model ◽  
Signaling Events ◽  
Toxic Responses

The role of long noncoding RNA FOXF1-AS1 as a tumor suppressor in non-small cell lung cancer

2016 ◽  
Vol 5 (S7) ◽  
pp. S1440-S1442 ◽  
Author(s):  
Hao Zheng ◽  
Aswini R. Krishnan ◽  
Angela E. Zou ◽  
Weg M. Ongkeko
Keyword(s):  
Lung Cancer ◽  
Tumor Suppressor ◽  
Small Cell Lung Cancer ◽  
Cell Lung Cancer ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Small Cell ◽  
Small Cell Lung

scholarly journals Involvement of the long noncoding RNA H19 in osteogenic differentiation and bone regeneration

2021 ◽  
Vol 12 (1) ◽  
Author(s):  
Zimo Zhou ◽  
Mohammad Showkat Hossain ◽  
Da Liu
Keyword(s):  
Bone Regeneration ◽  
Osteogenic Differentiation ◽  
Long Noncoding Rna ◽  
Noncoding Rna ◽  
Osteoblast Differentiation ◽  
Osteoclast Differentiation ◽  
Complex Processes ◽  
Osteogenic Induction ◽  
Novel Target

AbstractOsteogenic differentiation and bone regeneration are complex processes involving multiple genes and multiple steps. In this review, we summarize the effects of the long noncoding RNA (lncRNA) H19 on osteogenic differentiation.Osteogenic differentiation includes matrix secretion and calcium mineralization as hallmarks of osteoblast differentiation and the absorption of calcium and phosphorus as hallmarks of osteoclast differentiation. Mesenchymal stem cells (MSCs) form osteoprogenitor cells, pre-osteoblasts, mature osteoblasts, and osteocytes through induction and differentiation. lncRNAs regulate the expression of coding genes and play essential roles in osteogenic differentiation and bone regeneration. The lncRNA H19 is known to have vital roles in osteogenic induction.This review highlights the role of H19 as a novel target for osteogenic differentiation and the promotion of bone regeneration.

The functional role of tumor suppressor genes in gliomas: Clues for future therapeutic strategies

Neurology ◽  
1998 ◽  
Vol 51 (5) ◽  
pp. 1250-1255 ◽  
Author(s):  
J. Fueyo ◽  
C. Gomez-Manzano ◽  
W. K. Alfred Yung ◽  
A. P. Kyritsis
Keyword(s):  
Tumor Suppressor ◽  
Tumor Suppressor Genes ◽  
Functional Role ◽  
Therapeutic Strategies ◽  
Suppressor Genes
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