Subgroup analysis of olaparib monotherapy versus chemotherapy by hormone receptor and BRCA mutation status in patients with HER2-negative metastatic breast cancer and a germline BRCA mutation: OlympiAD

Subgroup Analysis ◽

Hormone Receptor ◽

Brca Mutation ◽

Metastatic Breast ◽

Mutation Status ◽

Abstract P5-21-13: Olaparib monotherapy versus chemotherapy for patients with HER2-negative metastatic breast cancer and a germline BRCA mutation: Asian subgroup analysis from the phase III OlympiAD trial

10.1158/1538-7445.sabcs17-p5-21-13 ◽

2018 ◽

Author(s):

S-A Im ◽

B Xu ◽

W Li ◽

M Robson ◽

Q Ouyang ◽

...

Keyword(s):

Breast Cancer ◽

Subgroup Analysis ◽

Brca Mutation ◽

Metastatic Breast ◽

Phase Iii ◽

A Real-World Evidence Study of CDK4/6 Inhibitor Treatment Patterns and Outcomes in Metastatic Breast Cancer by Germline BRCA Mutation Status

Oncology and Therapy ◽

10.1007/s40487-021-00162-4 ◽

2021 ◽

Author(s):

Jenna M. Collins ◽

Beth L. Nordstrom ◽

Kimmie K. McLaurin ◽

Tapashi B. Dalvi ◽

Susan C. McCutcheon ◽

...

Keyword(s):

Breast Cancer ◽

Real World ◽

Brca Mutation ◽

Metastatic Breast ◽

Treatment Patterns ◽

Mutation Status ◽

Real World Evidence ◽

Germline Brca Mutation ◽

Inhibitor Treatment

Olaparib monotherapy for Asian patients with a germline BRCA mutation and HER2-negative metastatic breast cancer: OlympiAD randomized trial subgroup analysis

Scientific Reports ◽

10.1038/s41598-020-63033-4 ◽

2020 ◽

Vol 10 (1) ◽

Author(s):

Seock-Ah Im ◽

Binghe Xu ◽

Wei Li ◽

Mark Robson ◽

Quchang Ouyang ◽

...

Keyword(s):

Breast Cancer ◽

Randomized Trial ◽

Subgroup Analysis ◽

Brca Mutation ◽

Metastatic Breast ◽

Asian Patients ◽

A Study of Fluzoparib±Apatinib Versus Chemotherapy Treatment of Physician's Choice in HER2-negative Metastatic Breast Cancer Patients With Germline BRCA Mutation

Case Medical Research ◽

10.31525/ct1-nct04296370 ◽

2020 ◽

Author(s):

Keyword(s):

Breast Cancer ◽

Cancer Patients ◽

Brca Mutation ◽

Metastatic Breast ◽

Breast Cancer Patients ◽

Chemotherapy Treatment ◽

Olaparib for Metastatic Breast Cancer in Patients with a Germline BRCA Mutation

New England Journal of Medicine ◽

10.1056/nejmx170012 ◽

2017 ◽

Vol 377 (17) ◽

pp. 1700-1700 ◽

Cited By ~ 6

Keyword(s):

Breast Cancer ◽

Brca Mutation ◽

Metastatic Breast ◽

Abstract OT1-1-14: A phase 2, 2-stage, 2-cohort study of the oral PARP inhibitor BMN 673 in patients with germline BRCA mutation and locally advanced and/or metastatic breast cancer (ABRAZO study)

10.1158/1538-7445.sabcs14-ot1-1-14 ◽

2015 ◽

Author(s):

Nicholas C Turner ◽

Judith Balmana ◽

Susan M Domchek ◽

Frances Visco ◽

Charlie Zhang ◽

...

Keyword(s):

Breast Cancer ◽

Cohort Study ◽

Brca Mutation ◽

Parp Inhibitor ◽

Locally Advanced ◽

Metastatic Breast ◽

Phase 2 ◽

A phase 2 study (2-stage, 2-cohort) of the oral PARP inhibitor talazoparib (BMN 673) in patients with germline BRCA mutation and locally advanced and/or metastatic breast cancer (ABRAZO).

Journal of Clinical Oncology ◽

10.1200/jco.2015.33.15_suppl.tps1108 ◽

2015 ◽

Vol 33 (15_suppl) ◽

pp. TPS1108-TPS1108 ◽

Cited By ~ 1

Author(s):

Nicholas C. Turner ◽

Judith Balmaña ◽

Peter A. Fasching ◽

Sara A. Hurvitz ◽

Melinda L. Telli ◽

...

Keyword(s):

Breast Cancer ◽

Brca Mutation ◽

Parp Inhibitor ◽

Locally Advanced ◽

Metastatic Breast ◽

Phase 2 ◽

Phase 2 Study ◽

Patient-reported outcomes in patients with a germline BRCA mutation and HER2-negative metastatic breast cancer receiving olaparib versus chemotherapy in the OlympiAD trial

European Journal of Cancer ◽

10.1016/j.ejca.2019.06.023 ◽

2019 ◽

Vol 120 ◽

pp. 20-30 ◽

Cited By ~ 6

Author(s):

Mark Robson ◽

Kathryn J. Ruddy ◽

Seock-Ah IM ◽

Elżbieta Senkus ◽

Binghe Xu ◽

...

Keyword(s):

Breast Cancer ◽

Patient Reported Outcomes ◽

Brca Mutation ◽

Metastatic Breast ◽

Patient Reported ◽

Faculty Opinions recommendation of Olaparib for Metastatic Breast Cancer in Patients with a Germline BRCA Mutation.

Faculty Opinions – Post-Publication Peer Review of the Biomedical Literature ◽

10.3410/f.727687763.793559064 ◽

2019 ◽

Author(s):

Ahmad Awada

Keyword(s):

Breast Cancer ◽

Brca Mutation ◽

Metastatic Breast ◽

Real-world clinical outcomes and treatment patterns among metastatic breast cancer (MBC) patients with germline BRCA mutation (gBRCAmut).

Journal of Clinical Oncology ◽

10.1200/jco.2018.36.15_suppl.e13075 ◽

2018 ◽

Vol 36 (15_suppl) ◽

pp. e13075-e13075

Author(s):

Ruben Quek ◽

Jack Mardekian

Keyword(s):

Breast Cancer ◽

Clinical Outcomes ◽

Real World ◽

Brca Mutation ◽

Metastatic Breast ◽

Treatment Patterns ◽