113 Is the breast-conserving treatment with radiotherapy appropriate in BRCA1/2 mutation carriers? Long term results and review of the literature

2010 ◽  
Vol 8 (3) ◽  
pp. 91-91
Author(s):  
Y. Kirova ◽  
A. Savignoni ◽  
B. Sigal-Zafrani ◽  
A. de La Rochefordiere ◽  
R. Salmon ◽  
...  
2009 ◽  
Vol 120 (1) ◽  
pp. 119-126 ◽  
Author(s):  
Youlia M. Kirova ◽  
Alexia Savignoni ◽  
Brigitte Sigal-Zafrani ◽  
Anne de La Rochefordiere ◽  
Rémy J. Salmon ◽  
...  

2019 ◽  
Vol 24 (1) ◽  
pp. 79-85 ◽  
Author(s):  
Anthony D. Honigman ◽  
Danielle P. Dubin ◽  
Justin Chu ◽  
Matthew J. Lin

Pearly penile papules (PPPs) are benign, dome-shaped lesions found around the corona of the penis. Despite being asymptomatic and benign in nature, the appearance of PPPs may cause a great deal of psychological distress to both the patient and their sexual partner. While patient reassurance may be the first-line treatment, several other treatment modalities including cryotherapy, electrodessication and curettage, and laser therapy have all been used to treat PPPs in order to achieve a cosmetic outcome that satisfies the patient. Based on the evaluation of the existing literature, ablative laser therapies offer satisfactory cosmetic outcomes with good long-term results.


Cancers ◽  
2021 ◽  
Vol 13 (20) ◽  
pp. 5107
Author(s):  
Diane Jornet ◽  
Pierre Loap ◽  
Jean-Yves Pierga ◽  
Fatima Laki ◽  
Anne Vincent-Salomon ◽  
...  

Background: Neoadjuvant concurrent radiochemotherapy makes it possible to increase the breast conservation rate. This study reports the long term outcome of this treatment. Methods: From 2001 to 2003, 59 women with T2–3 N0–2 M0 invasive breast cancer (BC) not amenable to upfront breast conserving treatment (BCS) were included in this prospective, non-randomized phase II study. Chemotherapy (CT) consisted of four cycles of continuous 5-FU infusion and Vinorelbine. Starting concurrently with the second CT cycle, normofractionated RT was delivered to the breast and LN. Breast surgery was then performed. Results: Median follow-up (FU) was 13 years [3–18]. BCS was performed in 41 (69%) patients and mastectomy in 18 patients, with pathological complete response rate of 27%. Overall and distant-disease free survivals rates at 13 years were 70.9% [95% CI 59.6–84.2] and 71.5% [95% CI 60.5–84.5] respectively. Loco regional and local controls rates were 83.4% [95% CI 73.2–95.0] and 92.1% [95% CI 83.7–100], respectively. Late toxicity (CTCAE-V3) was assessed in 51 patients (86%) with a median follow-up of 13 years. Fifteen presented grade 2 fibrosis (29.4%), 8 (15.7%) had telangiectasia, and 1 had radiodermatitis. Conclusions: This combined treatment provided high long-term local control rates with limited side-effects.


2005 ◽  
Vol 13 (3) ◽  
pp. 267-272 ◽  
Author(s):  
O Ozdemir ◽  
C Kurt ◽  
E Coskunol ◽  
I Calli ◽  
MH Ozsoy

1992 ◽  
Vol 82 (3) ◽  
pp. 162-166 ◽  
Author(s):  
CL Sands ◽  
N Daly ◽  
JM Karlin ◽  
BL Scurran

An unusual case of suspected lateral subtalar joint dislocation was reported. A review of the literature found that medial dislocations were reported four times more frequently than lateral dislocations. Half of the cases of subtalar dislocation reviewed here described associated fractures, the incidence of which was higher in lateral dislocations. In both types of dislocations examined, almost half were reduced nonoperatively. In most cases, long-term results of repair of these injuries were considered favorable.


2019 ◽  
Vol 276 (10) ◽  
pp. 2747-2754
Author(s):  
Filippo Di Lella ◽  
Ilaria Iaccarino ◽  
Maurizio Negri ◽  
Vincenzo Vincenti ◽  
Federica Canzano ◽  
...  

Author(s):  
Youlia M. Kirova ◽  
Francois Campana ◽  
Alexia Savignoni ◽  
Fatima Laki ◽  
Marius Muresan ◽  
...  

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