Discovery of subtype-selective metabotropic glutamate receptor ligands using functional HTS assays

Drug Discovery Today ◽

10.1016/s1359-6446(00)01499-9 ◽

2000 ◽

Vol 5 ◽

pp. 20-26 ◽

Author(s):

Mark A Varney ◽

Carla M Suto

Keyword(s):

Glutamate Receptor ◽

Metabotropic Glutamate Receptor ◽

Receptor Ligands ◽

Metabotropic Glutamate ◽

Subtype Selective

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Therapeutic potential of non-competitive, subtype-selective metabotropic glutamate receptor ligands

Expert Opinion on Therapeutic Patents ◽

10.1517/13543776.12.12.1845 ◽

2002 ◽

Vol 12 (12) ◽

pp. 1845-1852 ◽

Author(s):

Vincent Mutel

Keyword(s):

Glutamate Receptor ◽

Metabotropic Glutamate Receptor ◽

Therapeutic Potential ◽

Receptor Ligands ◽

Metabotropic Glutamate ◽

Subtype Selective

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S.04.05 The anxiolytic-like effects of metabotropic glutamate receptor ligands

European Neuropsychopharmacology ◽

10.1016/s0924-977x(05)80604-2 ◽

2005 ◽

Vol 15 ◽

pp. S321-S322

Keyword(s):

Glutamate Receptor ◽

Metabotropic Glutamate Receptor ◽

Receptor Ligands ◽

Metabotropic Glutamate

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Actions of group i and group ii metabotropic glutamate receptor ligands on 5-hydroxytryptamine release in the rat cerebral cortex in vivo: differential roles in the regulation of central serotonergic neurotransmission

Neuroscience ◽

10.1016/s0306-4522(02)00837-0 ◽

2003 ◽

Vol 117 (3) ◽

pp. 671-679 ◽

Author(s):

J.J Lee ◽

M.J Croucher

Keyword(s):

Cerebral Cortex ◽

Glutamate Receptor ◽

Metabotropic Glutamate Receptor ◽

Rat Cerebral Cortex ◽

Receptor Ligands ◽

Metabotropic Glutamate ◽

Serotonergic Neurotransmission ◽

Group I ◽

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Group-II metabotropic glutamate receptor ligands as adjunctive drugs in the treatment of depression: a new strategy to shorten the latency of antidepressant medication?

Molecular Psychiatry ◽

10.1038/sj.mp.4002005 ◽

2007 ◽

Vol 12 (8) ◽

pp. 704-706 ◽

Author(s):

F Matrisciano ◽

I Panaccione ◽

M Zusso ◽

P Giusti ◽

R Tatarelli ◽

...

Keyword(s):

Glutamate Receptor ◽

Metabotropic Glutamate Receptor ◽

Antidepressant Medication ◽

Receptor Ligands ◽

Metabotropic Glutamate ◽

Treatment Of Depression ◽

New Strategy ◽

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New perspectives for the development of selective metabotropic glutamate receptor ligands

European Journal of Pharmacology ◽

10.1016/s0014-2999(99)00258-7 ◽

1999 ◽

Vol 375 (1-3) ◽

pp. 277-294 ◽

Author(s):

Jean-Philippe Pin ◽

Cyril De Colle ◽

Anne-Sophie Bessis ◽

Francine Acher

Keyword(s):

Glutamate Receptor ◽

Metabotropic Glutamate Receptor ◽

Receptor Ligands ◽

Metabotropic Glutamate

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Effects of group II and III metabotropic glutamate receptor ligands on conditioned taste aversion learning

Behavioural Brain Research ◽

10.1016/j.bbr.2013.06.032 ◽

2013 ◽

Vol 253 ◽

pp. 9-16 ◽

Author(s):

D. Klakotskaia ◽

A.K. Ramsey ◽

S.W. Fowler ◽

P. Serfozo ◽

A. Simonyi ◽

...

Keyword(s):

Taste Aversion ◽

Glutamate Receptor ◽

Conditioned Taste Aversion ◽

Metabotropic Glutamate Receptor ◽

Aversion Learning ◽

Receptor Ligands ◽

Taste Aversion Learning ◽

Metabotropic Glutamate ◽

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Organocatalytic Enantioselective Synthesis of Metabotropic Glutamate Receptor Ligands

Organic Letters ◽

10.1021/ol0512942 ◽

2005 ◽

Vol 7 (18) ◽

pp. 3885-3888 ◽

Author(s):

Jeff T. Suri ◽

Derek D. Steiner ◽

Carlos F. Barbas

Keyword(s):

Glutamate Receptor ◽

Metabotropic Glutamate Receptor ◽

Enantioselective Synthesis ◽

Receptor Ligands ◽

Metabotropic Glutamate

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Attenuation of morphine withdrawal symptoms by subtype-selective metabotropic glutamate receptor antagonists

British Journal of Pharmacology ◽

10.1038/sj.bjp.0701000 ◽

1997 ◽

Vol 120 (6) ◽

pp. 1015-1020 ◽

Author(s):

Marian E Fundytus ◽

Jennifer Ritchie ◽

Terence J Coderre

Keyword(s):

Glutamate Receptor ◽

Metabotropic Glutamate Receptor ◽

Morphine Withdrawal ◽

Withdrawal Symptoms ◽

Receptor Antagonists ◽

Metabotropic Glutamate ◽

Glutamate Receptor Antagonists ◽

Subtype Selective

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Profiling of orthosteric and allosteric group-III metabotropic glutamate receptor ligands on various G protein-coupled receptors with Tag-lite® assays

Neuropharmacology ◽

10.1016/j.neuropharm.2018.07.032 ◽

2018 ◽

Vol 140 ◽

pp. 233-245 ◽

Author(s):

Abderazak Belhocine ◽

Pietro Veglianese ◽

Candide Hounsou ◽

Elodie Dupuis ◽

Francine Acher ◽

...

Keyword(s):

G Protein ◽

Glutamate Receptor ◽

Metabotropic Glutamate Receptor ◽

G Protein Coupled Receptors ◽

Receptor Ligands ◽

Group Iii ◽

Metabotropic Glutamate ◽

G Protein Coupled

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In vivo modulation of extracellular hippocampal glutamate and GABA levels and limbic seizures by group I and II metabotropic glutamate receptor ligands

Journal of Neurochemistry ◽

10.1046/j.1471-4159.2003.02251.x ◽

2004 ◽

Vol 88 (5) ◽

pp. 1068-1077 ◽

Author(s):

Ilse Smolders ◽

Hilde Lindekens ◽

Ralph Clinckers ◽

Alfred Meurs ◽

Michael J. O'Neill ◽

...

Keyword(s):

Glutamate Receptor ◽

Metabotropic Glutamate Receptor ◽

Receptor Ligands ◽

Limbic Seizures ◽

Metabotropic Glutamate ◽

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