P-164 Transoral laser resection of early supraglottic tumours, comparative quality of life study and cost benefit versus horizontal supraglottic laryngectomy

Oral Oncology ◽  
2021 ◽  
Vol 118 ◽  
pp. 18
Author(s):  
Miklos Csanady ◽  
Zoltan Tobias ◽  
Laszló Rovo
Keyword(s):  
Quality Of Life ◽  
Cost Benefit ◽  
Laser Resection ◽  
Life Study ◽  
Supraglottic Laryngectomy

Prophylaxis in people with haemophilia

2009 ◽  
Vol 101 (04) ◽  
pp. 674-681 ◽  
Author(s):  
Massimo Franchini ◽  
Annarita Tagliaferri ◽  
Antonio Coppola
Keyword(s):  
Quality Of Life ◽  
Cost Benefit ◽  
Primary Prophylaxis ◽  
Secondary Prophylaxis ◽  
Severe Haemophilia ◽  
Duration Of Treatment ◽  
First Choice ◽  
Long Term Treatment

SummaryA four-decade clinical experience and recent evidence from randomised controlled studies definitively recognised primary prophylaxis, i.e. the regular infusion of factor concentrates started after the first haemarthrosis and/or before the age of two years, as the first-choice treatment in children with severe haemophilia. The available data clearly show that preventing bleeding since an early age enables to avoid or reduce the clinical impact of muscle-skeletal impairment from haemophilic arthropathy and the related consequences in psycho-social development and quality of life of these patients. In this respect, the aim of secondary prophylaxis, defined as regular long-term treatment started after the age of two years or after two or more joint bleeds, is to avoid (or delay) the progression of arthropathy. The clinical benefits of secondary prophylaxis have been less extensively studied, especially in adolescents and adults; also in the latter better outcomes and quality of life for earlier treatment have been reported. This review summarises evidence from literature and current clinical strategies for prophylactic treatment in patients with severe haemophilia, also focusing on challenges and open issues (optimal regimen and implementation, duration of treatment, long-term adherence and outcomes, cost-benefit ratios) in this setting.

An open-label, multicenter, randomized, comparative, safety, efficacy, cycle control, and quality of life study of CTR 25, Alesse™, and Ortho Tri-Cyclen®

2004 ◽  
Vol 1271 ◽  
pp. 307-310
Author(s):  
Victoria Davis ◽  
Brian Hauck ◽  
Sheila Dunn ◽  
Marie Ann Jamieson ◽  
Robert Lea ◽  
...  
Keyword(s):  
Quality Of Life ◽  
Open Label ◽  
Life Study ◽  
Comparative Safety

PP017 Social Cost Benefit Analysis Of Cognitive Behavioral Therapy For Alcohol And Cannabis Addiction

2017 ◽  
Vol 33 (S1) ◽  
pp. 75-76
Author(s):  
Paul van Gils ◽  
Eelco Over ◽  
Anita Suijkerbuijk ◽  
Joran Lokkerbol ◽  
Ardine de Wit
Keyword(s):  
Quality Of Life ◽  
Traffic Accidents ◽  
Social Cost ◽  
Cost Benefit Analysis ◽  
Behavioral Therapy ◽  
Cost Benefit ◽  
Benefit Analysis ◽  
Costs And Benefits ◽  
Addiction Care

INTRODUCTION:Due to their chronic nature and high prevalence, alcohol and cannabis addiction leads to a significant (disease) burden and high costs, both for those involved and for society. The latter includes effects on health care, quality of life, employment, criminality, education, social security, violence in the public and private domain, and traffic accidents. In the Netherlands, a considerable number of people with an alcohol or cannabis addiction currently do not receive addiction care. Cognitive Behavioral Therapy (CBT) is effective as a treatment for both alcohol and cannabis addiction and is widely used in specialized addiction care centers. This social cost-benefit analysis (SCBA) models costs and benefits of increasing the uptake of CBT for persons with an alcohol addiction and for adolescents with a cannabis addiction, taking into account a wide range of social costs and effects (1).METHODS:The method follows general Dutch guidance for performing SCBA. A literature search was conducted to evaluate efficacy of CBT for alcohol and cannabis dependence. In addition, the social costs of alcohol and cannabis addiction for society were mapped, and the costs of enhancing the uptake of CBT were explored. Costs and benefits of increased uptake of CBT for different social domains were modeled for a ten year period, and compared with current (unchanged) uptake during this period. Compliance problems (about 50 percent of clients do not finish CBT) and fall-back to addiction behavior (decrease of effects of CBT over time) were taken into account in model estimations.RESULTS:Per client treated with CBT, the estimated benefits to society are EUR10,000-14,000 and EUR9,700-13,000, for alcohol and cannabis addiction, respectively. These benefits result from reduced morbidity and mortality, improved quality of life, higher productivity, fewer traffic accidents, and fewer criminal activities.CONCLUSIONS:This SCBA shows that not only treated clients but also society will benefit from an increase in people treated with CBT in specialized addiction care centers.

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