Combination of hyper-CVAD with ponatinib as first-line therapy for patients with Philadelphia chromosome-positive acute lymphoblastic leukaemia: a single-centre, phase 2 study

Elias Jabbour; Hagop Kantarjian; Farhad Ravandi; Deborah Thomas; Xuelin Huang; Stefan Faderl; Naveen Pemmaraju; Naval Daver; Guillermo Garcia-Manero; Koji Sasaki; Jorge Cortes; Rebecca Garris; C Cameron Yin; Joseph D Khoury; Jeffrey Jorgensen; Zeev Estrov; Zachary Bohannan; Marina Konopleva; Tapan Kadia; Nitin Jain; Courtney DiNardo; William Wierda; Vicky Jeanis; Susan O'Brien

doi:10.1016/s1470-2045(15)00207-7

Combination of hyper-CVAD with ponatinib as first-line therapy for patients with Philadelphia chromosome-positive acute lymphoblastic leukaemia: a single-centre, phase 2 study

The Lancet Oncology ◽

10.1016/s1470-2045(15)00207-7 ◽

2015 ◽

Vol 16 (15) ◽

pp. 1547-1555 ◽

Cited By ~ 143

Author(s):

Elias Jabbour ◽

Hagop Kantarjian ◽

Farhad Ravandi ◽

Deborah Thomas ◽

Xuelin Huang ◽

...

Keyword(s):

Acute Lymphoblastic Leukaemia ◽

Lymphoblastic Leukaemia ◽

Philadelphia Chromosome ◽

Phase 2 ◽

First Line ◽

Single Centre ◽

First Line Therapy ◽

Line Therapy ◽

Phase 2 Study ◽

Philadelphia Chromosome Positive

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Combination of hyper-CVAD with ponatinib as first-line therapy for patients with Philadelphia chromosome-positive acute lymphoblastic leukaemia: long-term follow-up of a single-centre, phase 2 study

The Lancet Haematology ◽

10.1016/s2352-3026(18)30176-5 ◽

2018 ◽

Vol 5 (12) ◽

pp. e618-e627 ◽

Cited By ~ 44

Author(s):

Elias Jabbour ◽

Nicholas J Short ◽

Farhad Ravandi ◽

Xuelin Huang ◽

Naval Daver ◽

...

Keyword(s):

Philadelphia Chromosome ◽

Phase 2 ◽

First Line ◽

Single Centre ◽

First Line Therapy ◽

Line Therapy ◽

Phase 2 Study ◽

Long Term Follow Up

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First-line therapy with dacomitinib, an orally available pan-HER tyrosine kinase inhibitor, for locally advanced or metastatic penile squamous cell carcinoma: results of an open-label, single-arm, single-centre, phase 2 study

BJU International ◽

10.1111/bju.14013 ◽

2017 ◽

Vol 121 (3) ◽

pp. 348-356 ◽

Cited By ~ 30

Author(s):

Andrea Necchi ◽

Salvatore Lo Vullo ◽

Federica Perrone ◽

Daniele Raggi ◽

Patrizia Giannatempo ◽

...

Keyword(s):

Kinase Inhibitor ◽

Locally Advanced ◽

Phase 2 ◽

First Line ◽

Single Centre ◽

Open Label ◽

First Line Therapy ◽

Line Therapy ◽

Phase 2 Study ◽

Penile Squamous Cell Carcinoma

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Phase 2 study of eribulin mesylate as first-line therapy for locally recurrent or metastatic human epidermal growth factor receptor 2-negative breast cancer

Breast Cancer Research and Treatment ◽

10.1007/s10549-014-2923-9 ◽

2014 ◽

Vol 146 (2) ◽

pp. 321-328 ◽

Cited By ~ 32

Author(s):

Kristi McIntyre ◽

Joyce O’Shaughnessy ◽

Lee Schwartzberg ◽

Stefan Glück ◽

Erhan Berrak ◽

...

Keyword(s):

Breast Cancer ◽

Growth Factor Receptor ◽

Phase 2 ◽

First Line ◽

Eribulin Mesylate ◽

First Line Therapy ◽

Line Therapy ◽

Phase 2 Study ◽

Epidermal Growth ◽

Locally Recurrent

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Erlotinib alone or with bevacizumab as first-line therapy in patients with advanced non-squamous non-small-cell lung cancer harbouring EGFR mutations (JO25567): an open-label, randomised, multicentre, phase 2 study

The Lancet Oncology ◽

10.1016/s1470-2045(14)70381-x ◽

2014 ◽

Vol 15 (11) ◽

pp. 1236-1244 ◽

Cited By ~ 383

Author(s):

Takashi Seto ◽

Terufumi Kato ◽

Makoto Nishio ◽

Koichi Goto ◽

Shinji Atagi ◽

...

Keyword(s):

Small Cell ◽

Egfr Mutations ◽

Phase 2 ◽

Small Cell Lung ◽

First Line ◽

Open Label ◽

Multicentre Phase ◽

First Line Therapy ◽

Line Therapy ◽

Phase 2 Study

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Etoposide and cisplatin versus irinotecan and cisplatin as the first‐line therapy for patients with advanced, poorly differentiated gastroenteropancreatic neuroendocrine carcinoma: A randomized phase 2 study

Cancer ◽

10.1002/cncr.32750 ◽

2020 ◽

Vol 126 (S9) ◽

pp. 2086-2092 ◽

Cited By ~ 1

Author(s):

Panpan Zhang ◽

Jie Li ◽

Jian Li ◽

Xiaotian Zhang ◽

Jun Zhou ◽

...

Keyword(s):

Neuroendocrine Carcinoma ◽

Phase 2 ◽

First Line ◽

First Line Therapy ◽

Line Therapy ◽

Phase 2 Study ◽

Poorly Differentiated ◽

Randomized Phase 2

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Abstract 4606: Randomized phase 2 study of efatutazone in combination with carboplatin and paclitaxel as first-line therapy for metastatic non-small cell lung cancer (NSCLC)

10.1158/1538-7445.am2012-4606 ◽

2012 ◽

Author(s):

Alice T. Shaw ◽

Doru Ghizdavescu ◽

Minish Jain ◽

Constantin Volovat ◽

Deepa Subramaniam ◽

...

Keyword(s):

Lung Cancer ◽

Small Cell Lung Cancer ◽

Small Cell ◽

Phase 2 ◽

Small Cell Lung ◽

First Line ◽

First Line Therapy ◽

Line Therapy ◽

Phase 2 Study ◽

Randomized Phase 2

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Weekly paclitaxel, capecitabine, and bevacizumab with maintenance capecitabine and bevacizumab as first-line therapy for triple-negative, metastatic, or locally advanced breast cancer: Results from the GINECO A-TaXel phase 2 study

Cancer ◽

10.1002/cncr.30170 ◽

2016 ◽

Vol 122 (20) ◽

pp. 3119-3126 ◽

Cited By ~ 8

Author(s):

Jean-Marc Ferrero ◽

Anne-Claire Hardy-Bessard ◽

Olivier Capitain ◽

Alain Lortholary ◽

Bruno Salles ◽

...

Keyword(s):

Breast Cancer ◽

Advanced Breast Cancer ◽

Triple Negative ◽

Locally Advanced Breast Cancer ◽

Locally Advanced ◽

Phase 2 ◽

First Line ◽

First Line Therapy ◽

Line Therapy ◽

Phase 2 Study

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Outcome and Biomarker Analysis from a Multicenter Phase 2 Study of Ipilimumab in Combination with Carboplatin and Etoposide as First-Line Therapy for Extensive-Stage SCLC

Journal of Thoracic Oncology ◽

10.1016/j.jtho.2016.05.028 ◽

2016 ◽

Vol 11 (9) ◽

pp. 1511-1521 ◽

Cited By ~ 43

Author(s):

Edurne Arriola ◽

Matthew Wheater ◽

Ian Galea ◽

Nadia Cross ◽

Tom Maishman ◽

...

Keyword(s):

Phase 2 ◽

First Line ◽

First Line Therapy ◽

Multicenter Phase ◽

Line Therapy ◽

Phase 2 Study ◽

Biomarker Analysis ◽

Extensive Stage

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Strong expansion of normal CD19‐negative B‐cell precursors after the use of blinatumomab in the first‐line therapy of acute lymphoblastic leukaemia in children

British Journal of Haematology ◽

10.1111/bjh.17760 ◽

2021 ◽

Author(s):

Ekaterina Mikhailova ◽

Julia Roumiantseva ◽

Olga Illarionova ◽

Svetlana Lagoyko ◽

Natalia Miakova ◽

...

Keyword(s):

Acute Lymphoblastic Leukaemia ◽

B Cell ◽

Lymphoblastic Leukaemia ◽

First Line ◽

First Line Therapy ◽

Line Therapy ◽

B Cell Precursors ◽

Strong Expansion

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Abstract CT139: First-line therapy with dacomitinib, an orally available pan-her tyrosine kinase inhibitor, for locally-advanced or metastatic penile squamous cell carcinoma: Results of an open label, single-arm, single-center, phase 2 study

10.1158/1538-7445.am2017-ct139 ◽

2017 ◽

Author(s):

Andrea Necchi ◽

Salvatore Lo Vullo ◽

Daniele Raggi ◽

Patrizia Giannatempo ◽

Nicola Nicolai ◽

...

Keyword(s):

Kinase Inhibitor ◽

Locally Advanced ◽

Phase 2 ◽

Single Center ◽

First Line ◽

Open Label ◽

First Line Therapy ◽

Line Therapy ◽

Phase 2 Study ◽

Penile Squamous Cell Carcinoma

Download Full-text