Effect of apalutamide on health-related quality of life in patients with non-metastatic castration-resistant prostate cancer: an analysis of the SPARTAN randomised, placebo-controlled, phase 3 trial

The Lancet Oncology ◽

10.1016/s1470-2045(18)30456-x ◽

2018 ◽

Vol 19 (10) ◽

pp. 1404-1416 ◽

Author(s):

Fred Saad ◽

David Cella ◽

Ethan Basch ◽

Boris A Hadaschik ◽

Paul N Mainwaring ◽

...

Keyword(s):

Quality Of Life ◽

Prostate Cancer ◽

Health Related Quality ◽

Castration Resistant Prostate Cancer ◽

Phase 3 ◽

Castration Resistant ◽

Related Quality ◽

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Assessment of health-related quality of life (HRQL) in PROSELICA: A Phase 3 trial assessing cabazitaxel 20 mg/m2 (C20) vs 25 mg/m2 (C25) in post-docetaxel (D) patients (pts) with metastatic castration-resistant prostate cancer (mCRPC)

Annals of Oncology ◽

10.1093/annonc/mdx370.027 ◽

2017 ◽

Vol 28 ◽

pp. v280-v281

Author(s):

M. Eisenberger ◽

A-C. Hardy-Bessard ◽

C.S. Kim ◽

L. Géczi ◽

D. Ford ◽

...

Keyword(s):

Quality Of Life ◽

Prostate Cancer ◽

Health Related Quality ◽

Castration Resistant Prostate Cancer ◽

Phase 3 ◽

Castration Resistant ◽

Related Quality ◽

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Effect of enzalutamide on health-related quality of life, pain, and skeletal-related events in asymptomatic and minimally symptomatic, chemotherapy-naive patients with metastatic castration-resistant prostate cancer (PREVAIL): results from a randomised, phase 3 trial

The Lancet Oncology ◽

10.1016/s1470-2045(15)70113-0 ◽

2015 ◽

Vol 16 (5) ◽

pp. 509-521 ◽

Author(s):

Yohann Loriot ◽

Kurt Miller ◽

Cora N Sternberg ◽

Karim Fizazi ◽

Johann S De Bono ◽

...

Keyword(s):

Quality Of Life ◽

Prostate Cancer ◽

Health Related Quality ◽

Castration Resistant Prostate Cancer ◽

Phase 3 ◽

Castration Resistant ◽

Related Quality ◽

Health Related ◽

Skeletal Related Events

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PROSELICA: Health-related quality of life (HRQL) and post-hoc analyses for the phase 3 study assessing cabazitaxel 20 (C20) vs 25 (C25) mg/m2 post-docetaxel (D) in patients (pts) with metastatic castration-resistant prostate cancer (mCRPC)

Annals of Oncology ◽

10.1093/annonc/mdw372.06 ◽

2016 ◽

Vol 27 ◽

pp. vi245

Author(s):

J.S. de Bono ◽

A.-C. Hardy-Bessard ◽

C.S. Kim ◽

L. Géczi ◽

D. Ford ◽

...

Keyword(s):

Quality Of Life ◽

Prostate Cancer ◽

Health Related Quality ◽

Castration Resistant Prostate Cancer ◽

Phase 3 ◽

Castration Resistant ◽

Related Quality ◽

Health Related ◽

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Health-related quality of life in men with metastatic castration–resistant prostate cancer

Expert Review of Pharmacoeconomics & Outcomes Research ◽

10.1586/14737167.2015.1107479 ◽

2015 ◽

Vol 15 (6) ◽

pp. 941-949 ◽

Author(s):

Abigail Gee ◽

Amarnath Challapalli ◽

Amit Bahl

Keyword(s):

Quality Of Life ◽

Prostate Cancer ◽

Health Related Quality ◽

Castration Resistant Prostate Cancer ◽

Castration Resistant ◽

Related Quality ◽

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PD14-11 HEALTH-RELATED QUALITY OF LIFE (HRQL) IN PATIENTS WITH METASTATIC CASTRATION-RESISTANT PROSTATE CANCER (MCRPC) TREATED WITH CABAZITAXEL (CBZ) IN A PROSPECTIVE OBSERVATIONAL STUDY (CAPRISTANA)

The Journal of Urology ◽

10.1016/j.juro.2018.02.797 ◽

2018 ◽

Vol 199 (4S) ◽

Author(s):

Angelika Pichler ◽

Gisoo Barnes ◽

Jana Katolicka ◽

Hana Korunkova ◽

Antoaneta Tomova ◽

...

Keyword(s):

Quality Of Life ◽

Prostate Cancer ◽

Observational Study ◽

Prospective Observational Study ◽

Health Related Quality ◽

Castration Resistant Prostate Cancer ◽

Castration Resistant ◽

Related Quality ◽

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576MO Health-related quality of life (HRQoL), pain and safety outcomes in the phase III VISION study of 177Lu-PSMA-617 in patients with metastatic castration-resistant prostate cancer

Annals of Oncology ◽

10.1016/j.annonc.2021.08.1089 ◽

2021 ◽

Vol 32 ◽

pp. S627-S628

Author(s):

K. Fizazi ◽

K. Herrmann ◽

B.J. Krause ◽

K. Rahbar ◽

K.N. Chi ◽

...

Keyword(s):

Quality Of Life ◽

Prostate Cancer ◽

Phase Iii ◽

Health Related Quality ◽

Castration Resistant Prostate Cancer ◽

Castration Resistant ◽

Safety Outcomes ◽

Related Quality ◽

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Health-related quality of life (HRQoL) deterioration and pain progression in men with non-metastatic castration-resistant prostate cancer (M0 CRPC): Results from the PROSPER study.

Journal of Clinical Oncology ◽

10.1200/jco.2018.36.15_suppl.5010 ◽

2018 ◽

Vol 36 (15_suppl) ◽

pp. 5010-5010 ◽

Author(s):

Gerhardt Attard ◽

Fred Saad ◽

Bertrand F. TOMBAL ◽

Maha Hussain ◽

Cora N. Sternberg ◽

...

Keyword(s):

Quality Of Life ◽

Prostate Cancer ◽

Health Related Quality ◽

Castration Resistant Prostate Cancer ◽

Castration Resistant ◽

Related Quality ◽

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Recent Advances In The Treatment Of Metastatic Castration Resistant Prostate Cancer: Impact On Health Related Quality Of Life

Value in Health ◽

10.1016/j.jval.2013.03.719 ◽

2013 ◽

Vol 16 (3) ◽

pp. A146-A147 ◽

Author(s):

Y. Hao ◽

C. Evans ◽

S. Hwang

Keyword(s):

Quality Of Life ◽

Prostate Cancer ◽

Health Related Quality ◽

Castration Resistant Prostate Cancer ◽

Castration Resistant ◽

Recent Advances ◽

Related Quality ◽

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Darolutamide and health-related quality of life in patients with non-metastatic castration-resistant prostate cancer: An analysis of the phase III ARAMIS trial

European Journal of Cancer ◽

10.1016/j.ejca.2021.06.010 ◽

2021 ◽

Vol 154 ◽

pp. 138-146

Author(s):

Matthew R. Smith ◽

Neal Shore ◽

Teuvo L. Tammela ◽

Albertas Ulys ◽

Egils Vjaters ◽

...

Keyword(s):

Quality Of Life ◽

Prostate Cancer ◽

Phase Iii ◽

Health Related Quality ◽

Castration Resistant Prostate Cancer ◽

Castration Resistant ◽

Related Quality ◽

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Assessment of Health-Related Quality of Life in Patients with Advanced Prostate Cancer—Current State and Future Perspectives

Cancers ◽

10.3390/cancers14010147 ◽

2021 ◽

Vol 14 (1) ◽

pp. 147

Author(s):

Alexander Kretschmer ◽

Roderick C. N. van den Bergh ◽

Alberto Martini ◽

Giancarlo Marra ◽

Massimo Valerio ◽

...

Keyword(s):

Quality Of Life ◽

Prostate Cancer ◽

Advanced Prostate Cancer ◽

Health Related Quality ◽

Castration Resistant Prostate Cancer ◽

Castration Resistant ◽

Clinical Scenarios ◽

Related Quality ◽

With the therapeutic landscape of advanced prostate cancer rapidly evolving and oncological benefits being shown for a plethora of new agents and indications, health-related quality of life (HRQOL)-associated evidence is still subpar. In the current comprehensive review, we discuss the importance of HRQOL for patients with advanced PC (metastatic hormone-sensitive prostate cancer (mHSPC), metastatic castration-resistant prostate cancer (mCRPC) and non-metastatic castration-resistant prostate cancer (nmCRPC)), and present the most frequently used tools to evaluate HRQOL in recent randomized trials. Furthermore, we discuss the ease of use of these validated questionnaires for clinicians and try to focus on the suggested appropriate use in clinical practice, as well as potential strategies for improvement of HRQOL evaluation in these clinical scenarios of advanced prostate cancer.

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