296 Mitral annulus calcification highly correlates with valvular regurgitation, left atrial enlargement and left ventricular hypertrophy

2004 ◽  
Vol 3 (1) ◽  
pp. 72
Author(s):  
M MOVAHED
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Left Atrial ◽  
Ventricular Hypertrophy ◽  
Mitral Annulus ◽  
Left Ventricular ◽  
Valvular Regurgitation ◽  
Left Atrial Enlargement ◽  
Mitral Annulus Calcification ◽  
Atrial Enlargement

Utility of serial 12-lead electrocardiograms in children with Marfan syndrome

2018 ◽  
Vol 28 (8) ◽  
pp. 1009-1013 ◽  
Author(s):  
Alisa A. Arunamata ◽  
Charles T. Nguyen ◽  
Scott R. Ceresnak ◽  
Anne M. Dubin ◽  
Inger L. Olson ◽  
...  
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Marfan Syndrome ◽  
Race And Ethnicity ◽  
Left Atrial ◽  
Ventricular Hypertrophy ◽  
Left Ventricular ◽  
Qtc Interval ◽  
Left Atrial Enlargement ◽  
Atrial Enlargement

AbstractObjectivesThe goal of this study was to assess the utility of serial electrocardiograms in routine follow-up of paediatric Marfan patients.MethodsChildren ⩽18 years who met the revised Ghent criteria for Marfan syndrome and received a 12-lead electrocardiogram and echocardiogram within a 3-month period were included. Controls were matched by age, body surface area, gender, race, and ethnicity, and consisted of patients assessed in clinic with a normal cardiac evaluation. Demographic, clinical, echocardiographic, and electrocardiographic data were collected.ResultsA total of 45 Marfan patients (10.8 [2.4–17.1] years) and 37 controls (12.8 [1.3–17.1] years) were included. Left atrial enlargement and left ventricular hypertrophy were more frequently present on 12-lead electrocardiogram of Marfan patients compared with controls (12 (27%) versus 0 (0%), p<0.001; and 8 (18%) versus 0 (0%), p=0.008, respectively); however, only two patients with left atrial enlargement on 12-lead electrocardiogram were confirmed to have left atrial enlargement by echocardiogram, and one patient had mild left ventricular hypertrophy by echocardiogram, not appreciated on 12-lead electrocardiogram. QTc interval was longer in Marfan patients compared with controls (427±16 versus 417±22 ms, p=0.03), with four Marfan patients demonstrating borderline prolonged QTc intervals for gender.ConclusionsWhile Marfan patients exhibited a higher frequency of left atrial enlargement and left ventricular hypertrophy on 12-lead electrocardiograms compared with controls, these findings were not supported by echocardiography. Serial 12-lead electrocardiograms in routine follow-up of asymptomatic paediatric Marfan patients may be more appropriate for a subgroup of Marfan patients only, specifically those with prolonged QTc interval at their baseline visit.

P313The automatically assessed P-wave axis predicts cardiovascular events in patients with cardiovascular risks: The Japan Morning Surge Home Blood Pressure (J-HOP) Study

EP Europace ◽  
2020 ◽  
Vol 22 (Supplement_1) ◽  
Author(s):  
T Kabutoya ◽  
S Hoshide ◽  
K Kario
Keyword(s):  
Cardiovascular Risk ◽  
Left Ventricular Hypertrophy ◽  
Left Atrial ◽  
Cardiovascular Events ◽  
Ventricular Hypertrophy ◽  
Left Ventricular ◽  
P Wave ◽  
Axis Deviation ◽  
Left Atrial Enlargement ◽  
Atrial Enlargement

Abstract Background An abnormal P-wave axis in electrocardiography predicts the development of atrial fibrillation (AF) and cardiovascular events. There have been few reports on the relationships among an automatically assessed P-wave duration, left atrial enlargement, left ventricular hypertrophy, and cardiovascular events in patients with cardiovascular risk factors.  Purpose To determine the relationship among an abnormal P-wave axis,  left atrial enlargement, left ventricular hypertrophy, and cardiovascular events in patients with cardiovascular risk factors.  Methods We enrolled 829 subjects from the J-HOP Study who had ≥1 of four cardiovascular risk factors: hypertension, dyslipidemia, diabetes, and smoking. Twelve-lead electrocardiography was conducted, and the P-wave axis was calculated automatically using a 12-lead ECG Analysis system (Fukuda Denshi, Tokyo) according to the following formula: arctan{√3(II + III) / (2I + II-III)}. We divided the patients into three groups: those with a normal axis (0°–75°, n = 692), left axis deviation (&lt;0°, n = 39), or right axis deviation (≥75°, n = 56). The primary endpoints were fatal/nonfatal cardiovascular events: myocardial infarction, stroke, hospitalization for heart failure, and aortic dissection. We conducted echocardiography and measured the left atrial (LA) diameter, left ventricular mass index (LVMI), and brain natriuretic peptide (BNP).  Results The LA diameter, LVMI, and BNP in the patients with left axis deviation were significantly higher than those in the patients with a normal axis (LA diameter: 40.2 ± 7.0 vs. 37.0 ± 5.0, p = 0.008; LVMI: 105.7 ± 25.7 vs. 96.9 ± 25.2 g/m2, p &lt; 0.001; median BNP: 41.6 vs. 16.5 pg/dL, p &lt; 0.001). The mean follow-up period was 101 ± 34 months, and 92 cardiovascular events occurred. A Cox proportional hazards model including age, gender, smoking, history of hypertension, dyslipidemia, diabetes, LA dia., and LVMI revealed that left axis deviation of the P wave was independently associated with cardiovascular events (hazard ratio 2.31, 95%CI 1.18–4.55, p = 0.015). Conclusions: Leftward deviation of the automatically assessed P-wave axis was associated with left atrial enlargement, left ventricular hypertrophy, and cardiovascular events in patients with cardiovascular risk.

Left atrial systolic force in hypertensive patients with left ventricular hypertrophy: the LIFE study

2008 ◽  
Vol 26 (7) ◽  
pp. 1472-1476 ◽  
Author(s):  
Marcello Chinali ◽  
Giovanni de Simone ◽  
Kristian Wachtell ◽  
Eva Gerdts ◽  
Julius M Gardin ◽  
...  
Keyword(s):  
Left Ventricular Hypertrophy ◽  
Left Atrial ◽  
Ventricular Hypertrophy ◽  
Left Ventricular ◽  
Hypertensive Patients ◽  
Life Study

Blood Pressure Control and Left Ventricular Hypertrophy in Long-Term Capd and Hemodialysis Patients: A Cross-Sectional Study

2003 ◽  
Vol 23 (6) ◽  
pp. 563-567 ◽  
Author(s):  
Ali Ihsan Günal ◽  
Erdogan Ilkay ◽  
Ercan Kirciman ◽  
Ilgin Karaca ◽  
Ayhan Dogukan ◽  
...  
Keyword(s):  
Blood Pressure ◽  
Left Ventricular Hypertrophy ◽  
Wall Thickness ◽  
Left Atrial ◽  
Ventricular Hypertrophy ◽  
Left Ventricular ◽  
Volume Control ◽  
Left Ventricular Chamber ◽  
Significant Difference

Background It is still not clear whether hypertension and left ventricular hypertrophy (LVH) are more common in continuous ambulatory peritoneal dialysis (CAPD) than in hemodialysis (HD) patients. Methods To examine this subject, the indices of cardiac performance were compared between 50 HD and 34 CAPD patients. Patients were further divided into two subgroups [long-term (L) CAPD and L-HD] according to dialysis modality and duration of dialysis (more than 60 months’ duration). Results The blood pressure and cardiothoracic index of CAPD patients did not differ from HD patients. On average, the left atrial index was 2 mm/m2 higher in HD patients than in CAPD patients. Left ventricular chamber sizes, wall thickness, and left ventricular mass index (LVMI) in patients on CAPD were similar to those of HD patients. Isovolumic relaxation time (IVRT) of CAPD patients was insignificantly less than that of HD patients (101 ± 22 and 115 ± 27 msec respectively). There was no significant difference between the two subgroups (L-HD and L-CAPD) in blood pressure, left atrial diameter, left ventricular chamber size, wall thickness, LVMI, ejection fraction, or IVRT. Conclusion If normovolemia and normotension are obtained by strict volume control without using antihypertensive drugs, the effects of the two modalities of chronic dialysis treatment (HD and CAPD) on cardiac structure and function are not different from each other.

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