Oncological prognostic factors in intermediate risk prostate cancer after laparoscopic radical prostatectomy: 15 years of experience

2019 ◽  
Vol 18 (11) ◽  
pp. e3444-e3445
Author(s):  
J.M.E. Quesada Olarte
Keyword(s):  
Prostate Cancer ◽  
Prognostic Factors ◽  
Radical Prostatectomy ◽  
Laparoscopic Radical Prostatectomy ◽  
Intermediate Risk ◽  
Years Of Experience ◽  
Risk Prostate Cancer

scholarly journals Treatment outcomes of 125I low-dose-rate brachytherapy vs radical prostatectomy for patients with intermediate-risk prostate cancer

2020 ◽  
Author(s):  
Zhien Zhou ◽  
Meiting He ◽  
Yi Zhou ◽  
Weigang Yan ◽  
Xingcheng Wu ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Dose Rate ◽  
Low Dose ◽  
Intermediate Risk ◽  
Relapse Free Survival ◽  
Free Survival ◽  
Low Dose Rate ◽  
Risk Prostate Cancer ◽  
Low Dose Rate Brachytherapy

Abstract Background: Radical prostatectomy (RP) and low-dose-rate brachytherapy (LDR) are two widely used treatment options for patients with intermediate-risk prostate cancer (IRPC). However, which one is better remains controversial. Therefore, the purpose of this study was to compare the efficacy of RP vs LDR for patients with IRPC. Methods: A retrospective analysis was performed on 361 IRPC patients who underwent treatment from January 2010 and August 2017. 160 underwent RP and 201 underwent LDR using Iodine-125. Biochemical failure for RP was defined as prostate-specific antigen (PSA) levels > 0.2 ng/ml, and for LDR as nadir PSA level + 2 ng/ml. The log-rank test compared biochemical relapse-free survival (bRFS) between the two modalities, and Cox regression identified factors associated with bRFS. Results: Median follow-up was 54 months for RP and 69 months for LDR. The 5-and 8-year bRFS rates were 70.2% and 63.1% in the RP group, and 83.2% and 68.9% in the LDR group, respectively, P=0.003. There were no significant differences in terms of clinical relapse-free survival (cRFS), cancer-specific survival (CSS) or overall survival (OS) between the two groups. Conclusion: LDR is a reasonable treatment option for IRPC patients, yielding improved bRFS and equivalent rates of cRFS, CSS and OS compared with RP.

Role of laparoscopic radical prostatectomy in locally advanced and high-risk prostate cancer: Whether safe and effective approach?

2021 ◽  
Vol 4 (1) ◽  
pp. 5
Author(s):  
SanjeetK Singh ◽  
GurunamSingh Girniwale ◽  
Alok Srivastava ◽  
Anjana Singh ◽  
Chandrakant Munjewar
Keyword(s):  
Prostate Cancer ◽  
High Risk ◽  
Radical Prostatectomy ◽  
Locally Advanced ◽  
Laparoscopic Radical Prostatectomy ◽  
High Risk Prostate Cancer ◽  
Risk Prostate Cancer

Pathologic Outcomes of Gleason 6 Favorable Intermediate-Risk Prostate Cancer Treated With Radical Prostatectomy: Implications for Active Surveillance

2018 ◽  
Vol 16 (3) ◽  
pp. 226-234 ◽  
Author(s):  
David D. Yang ◽  
Brandon A. Mahal ◽  
Vinayak Muralidhar ◽  
Marie E. Vastola ◽  
Ninjin Boldbaatar ◽  
...  
Keyword(s):  
Prostate Cancer ◽  
Radical Prostatectomy ◽  
Active Surveillance ◽  
Intermediate Risk ◽  
Risk Prostate Cancer
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