scholarly journals P077 DEMOGRAPHIC AND DISEASE-RELATED FACTORS INFLUENCING ASSESSMENT OF DISEASE ACTIVITY IN CROHN'S DISEASE

2008 ◽  
Vol 2 (1) ◽  
pp. 28
Author(s):  
H.C.R. Stjernman ◽  
C. Tysk ◽  
S. Almer ◽  
M. Ström ◽  
H. Hjortswang
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Disease Activity ◽  
Related Factors ◽  
Factors Influencing ◽  
Assessment Of Disease Activity

Tu1213 Reproducibility of Magnetic Resonance Enterography Assessment of Disease Activity in Crohn's Disease Using Central Readers

2015 ◽  
Vol 148 (4) ◽  
pp. S-824 ◽  
Author(s):  
Ingrid Ordás ◽  
Jordi Rimola ◽  
Guangyong Zou ◽  
Cynthia Santillan ◽  
Karin Horsthuis ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Magnetic Resonance ◽  
Crohn's Disease ◽  
Disease Activity ◽  
Magnetic Resonance Enterography ◽  
Assessment Of Disease Activity

scholarly journals 486 Are Surgical Resection Margins A Risk Factor for Crohn’s Disease Recurrence?

2021 ◽  
Vol 108 (Supplement_2) ◽  
Author(s):  
A A Haiduc ◽  
R Patel ◽  
A Karim
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Disease Activity ◽  
Surgical Resection ◽  
Colonic Resection ◽  
Sufficient Evidence ◽  
Resection Margins ◽  
Related Factors ◽  
Clinical Recurrence ◽  
Disease Free

Abstract Despite advances in treatment, Crohn’s disease (CD) recurrence is still high. Various factors correlated with recurrence are studied however, there is no consensus regarding the importance of disease-free resection margins. Our goal was to ascertain whether surgical margins predict recurrence rates of CD and identify other potential factors correlated with recurrence. This is a retrospective cohort study on patients who have had a colonic resection for CD from December 2016 to November 2019. Demographics, surgical procedure details, disease activity at resection margins and number of readmissions were recorded. Clinical recurrence was defined as readmission to hospital for a Crohn’s related flare-up within 12 months of surgical resection. Positive disease activity at the resection margins was defined histologically. We compared the readmission rate between all categories. Of the 55 patients identified, 52 (22 female) were included. Of these, seven were readmitted, six are smokers, 19 had mesenteric excision and 33 had Crohn’s positive resection margins. Chi-squared tests showed there are no significant correlations between patient and procedure variables, and readmission rates (p > 0.05). We have not found sufficient evidence to conclude that a disease-free resection margin post colonic resection or any other patient-related factors are associated with decreased recurrence of CD.

Dynamic Contrast-Enhanced MRI of the Bowel Wall for Assessment of Disease Activity in Crohn's Disease

2006 ◽  
Vol 186 (5) ◽  
pp. 1384-1392 ◽  
Author(s):  
Jasper Florie ◽  
Martin N. J. M. Wasser ◽  
Kasia Arts-Cieslik ◽  
Erik M. Akkerman ◽  
Peter D. Siersema ◽  
...  
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Disease Activity ◽  
Bowel Wall ◽  
Dynamic Contrast Enhanced Mri ◽  
Dynamic Contrast Enhanced ◽  
Enhanced Mri ◽  
Contrast Enhanced ◽  
Assessment Of Disease Activity ◽  
Contrast Enhanced Mri

scholarly journals An Analysis of Crohn’s Disease Activity Indices from a Registry of Patients in Eastern Pennsylvania

1991 ◽  
Vol 5 (6) ◽  
pp. 199-208 ◽  
Author(s):  
JF Reed ◽  
Linda A Faust
Keyword(s):  
Crohn’S Disease ◽  
Crohn's Disease ◽  
Disease Activity ◽  
Disease Patient ◽  
Weighted Kappa ◽  
Well Being ◽  
Eastern Pennsylvania ◽  
Disease Study ◽  
National Cooperative ◽  
Assessment Of Disease Activity

The objectives of this report were to compare Crohn’s disease patients’ assessment of disease activity and its effect on their well-being to their physician’s assessment of the disease activity and the patient’s well-being; and to use existing Crohn’s disease indices in comparing the severity of Crohn’s disease across various indices. The indices included in this study were the National Cooperative Crohn’s Disease Study index, the Harvey and Bradshaw Index, the Oxford Index, the Modified Organisation Mondiale de Gastroentérologie Index, the Cape Town Index, the Bristol Index, and the St Marks Index. The comparison of Crohn’s disease patient self-evaluation and physician evaluation of the patient indicates a significant agreement between patient and physician assessment of disease activity (Χ241.68, P=0.00001). Cohen’s weighted kappa, a chance-corrected coefficient of agreement for nominal scales, was also used to evaluate the quality of agreement between physician and patient assessment of well-being. The weighted kappa (0.2322, P=0.0002) indicates a significant level of agreement.

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