scholarly journals Effectiveness and cost-effectiveness of group support psychotherapy delivered by trained lay health workers for depression treatment among people with HIV in Uganda: a cluster-randomised trial

2020 ◽  
Vol 8 (3) ◽  
pp. e387-e398 ◽  
Author(s):  
Etheldreda Nakimuli-Mpungu ◽  
Seggane Musisi ◽  
Kizito Wamala ◽  
James Okello ◽  
Sheila Ndyanabangi ◽  
...  
2018 ◽  
Vol 3 (1) ◽  
pp. e000577 ◽  
Author(s):  
Jane Goudge ◽  
Tobias Chirwa ◽  
Sandra Eldridge ◽  
Francesc Xavier F Gómez-Olivé ◽  
Chodziwadziwa Kabudula ◽  
...  

IntroductionIn low/middle-income countries with substantial HIV and tuberculosis epidemics, health services often neglect other highly prevalent chronic conditions, such as hypertension, which as a result are poorly managed. This paper reports on a study to assess the effect on hypertension management of lay health workers (LHW) working in South African rural primary healthcare clinics to support the provision of integrated chronic care.MethodsA pragmatic cluster randomised trial with a process evaluation in eight rural clinics assessed the effect of adding two LHWs supporting nurses in providing chronic disease care in each intervention clinic over 18 months. Control clinics continued with usual care. The main outcome measure was the change in the difference of percentage of clinic users who had elevated cardiovascular risk associated with high blood pressure (BP) before and after the intervention, as measured by two cross-sectional population surveys.ResultsThere was no improvement in BP control among users of intervention clinics as compared with control clinics. However, the LHWs improved clinic functioning, including overall attendance, and attendance on the correct day. All clinics faced numerous challenges, including rapidly increasing number of users of chronic care, unreliable BP machines and cuffs, intermittent drug shortages and insufficient space.ConclusionLHWs improved the process of providing care but improved BP control required improved clinical care by nurses which was compromised by large and increasing numbers of patients, the dominance of the vertically funded HIV programme and the poor standards of equipment in clinics.Trial registration numberISRCTN12128227.


BMJ Open ◽  
2015 ◽  
Vol 5 (10) ◽  
pp. e007284 ◽  
Author(s):  
Melinde R S Boland ◽  
Annemarije L Kruis ◽  
Apostolos Tsiachristas ◽  
Willem J J Assendelft ◽  
Jacobijn Gussekloo ◽  
...  

2018 ◽  
Vol 213 (2) ◽  
pp. 456-463 ◽  
Author(s):  
Elizabeth M. Camacho ◽  
Linda M. Davies ◽  
Mark Hann ◽  
Nicola Small ◽  
Peter Bower ◽  
...  

BackgroundCollaborative care can support the treatment of depression in people with long-term conditions, but long-term benefits and costs are unknown.AimsTo explore the long-term (24-month) effectiveness and cost-effectiveness of collaborative care in people with mental-physical multimorbidity.MethodA cluster randomised trial compared collaborative care (integrated physical and mental healthcare) with usual care for depression alongside diabetes and/or coronary heart disease. Depression symptoms were measured by the symptom checklist-depression scale (SCL-D13). The economic evaluation was from the perspective of the English National Health Service.Results191 participants were allocated to collaborative care and 196 to usual care. At 24 months, the mean SCL-D13 score was 0.27 (95% CI, −0.48 to −0.06) lower in the collaborative care group alongside a gain of 0.14 (95% CI, 0.06-0.21) quality-adjusted life-years (QALYs). The cost per QALY gained was £13 069.ConclusionsIn the long term, collaborative care reduces depression and is potentially cost-effective at internationally accepted willingness-to-pay thresholds.Declaration of interestNone.


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