scholarly journals International consensus on a standard set of outcome measures for child and youth anxiety, depression, obsessive-compulsive disorder, and post-traumatic stress disorder

2021 ◽  
Vol 8 (1) ◽  
pp. 76-86
Author(s):  
Karolin R Krause ◽  
Sophie Chung ◽  
Abiodun O Adewuya ◽  
Anne Marie Albano ◽  
Rochelle Babins-Wagner ◽  
...  
Keyword(s):  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Post Traumatic Stress ◽  
Obsessive Compulsive ◽  
International Consensus ◽  
Compulsive Disorder ◽  
Youth Anxiety ◽  
Post Traumatic ◽  
Standard Set ◽  
Anxiety Depression

scholarly journals B-41 SPECT Differences between Obsessive Compulsive Disorder and Post-Traumatic Stress Disorder (PTSD)

2019 ◽  
Vol 34 (6) ◽  
pp. 987-987
Author(s):  
D Lopez Palacios ◽  
A Lopez ◽  
B McDonald ◽  
C Golden ◽  
D Amen ◽  
...  
Keyword(s):  
Obsessive Compulsive Disorder ◽  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Stress Disorder ◽  
Photon Emission ◽  
Emission Computed Tomography ◽  
Post Traumatic Stress ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Post Traumatic

Abstract Objective To assess whether diagnosed Obsessive Compulsive Disorder (OCD) and Post Traumatic Stress Disorder (PTSD) interactively alter brain activity, as measured by a Single Photon Emission Computed Tomography (SPECT) imaging. Method The sample included adults diagnosed with OCD (n = 915) with a mean age of 34.65 and predominantly male (68.6%) and adults with PTSD (n = 1,481) which had a mean age of 41.33 and was predominantly female (57.2%). Significant differences were observed for gender . Multiple ANCOVAs were conducted to determine differences between cerebral blood flow (CBF)in 17 different brain regions. Results Results showed hyper-perfusion in the PTSD group as compared to the OCD group in the pariental L/R[F(1,2393) = 6.47,p < 0.01/F(1,2393) = 12.31,p < .01], motor sensory L/R[F(1,2393) = 19.33,p < .001/F(1,2393) = 17.32,p < .01] and temporal left [F(1,2393) = 12.49,p < .01]. Conclusion Significantly higher rCBF in the pariental and motor sensory for OCD individuals may be due to visual-constructive and controlled fluency which are usually associated with compulsion. Due to the hyperalert nature related with OCD rituals, these areas are more active when compared to PTSD. Hyperfusion was reported for PTSD in the left temporal lobe compared to OCD, this region is usually associated with registering potential threasts in the environment. This can be explained by the hypervigilant conduct seen in individuals with PTSD. Overall, it appears that individuals with OCD struggle with continual inability to inhibit repetitive thoughts and behaviors due to the over activation in the motor sensory and parietal region. Alternatively, the activation in PTSD individuals can be a result of a way to help them cope with threats in the environment.

Ketamine’s dose-related effects on anxiety symptoms in patients with treatment refractory anxiety disorders

2017 ◽  
Vol 31 (10) ◽  
pp. 1302-1305 ◽  
Author(s):  
Paul Glue ◽  
Natalie J Medlicott ◽  
Sarah Harland ◽  
Shona Neehoff ◽  
Bridie Anderson-Fahey ◽  
...  
Keyword(s):  
Anxiety Disorder ◽  
Anxiety Disorders ◽  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Post Traumatic Stress ◽  
Treatment Resistant ◽  
Obsessive Compulsive ◽  
Compulsive Disorder ◽  
Post Traumatic ◽  
Resistant Depression

The N-methyl-D-aspartate receptor antagonist ketamine has rapid onset activity in treatment-resistant depression, post-traumatic stress disorder and obsessive compulsive disorder. Due to similarities in brain network activity in depression and anxiety disorders, we hypothesized that ketamine might also be active in other refractory anxiety disorders. We evaluated the efficacy and safety of ketamine in 12 patients with refractory generalized anxiety disorder and/or social anxiety disorder who were not currently depressed, using an ascending single dose study design (0.25, 0.5, 1 mg/kg administered subcutaneously) at weekly intervals. Within 1 h of dosing, patients reported reduced anxiety, which persisted for up to seven days. A dose-response profile was noted for anxiolytic effects, dissociative side effects, and changes in blood pressure and heart rate, with minor changes at 0.25 mg/kg, and progressively greater and more durable changes at the higher doses. Ten of 12 patients were treatment responders at 0.5–1 mg/kg. Ketamine was safe and well tolerated in this population. Ketamine may be a potential therapeutic alternative for patients with refractory generalized anxiety disorder/social anxiety disorder. Along with its demonstrated effectiveness in patients with treatment-resistant depression, obsessive compulsive disorder and post-traumatic stress disorder, these data raise the intriguing possibility that ketamine may have broad efficacy in disorders characterized by negative emotional states, and that these disorders may share a common precipitating neurobiology.

scholarly journals CAUSES AND EFFECTS OF THE PROTAGONIST’S WORRY IN DANIELLE STEEL’S NOVEL FAMILY TIES

2020 ◽  
Vol 3 (1) ◽  
pp. 60-69
Author(s):  
Muhammad Ikhsan ◽  
Susi Ekalestari
Keyword(s):  
Post Traumatic Stress Disorder ◽  
Traumatic Stress ◽  
Qualitative Method ◽  
Human Life ◽  
The Novel ◽  
Post Traumatic Stress ◽  
Obsessive Compulsive ◽  
Family Ties ◽  
Compulsive Disorder ◽  
Post Traumatic

This research analyses the causes and effects of the protagonist’s worry in Danielle Steel’s novel Family Ties,  a story of woman, Annie Ferguson, who must become a mother in her bachelorette. She always worries about the future of her sister’s children. This research applied the theory of worry proposed by Graham (2006), who said that worry is “prominent feature of most anxiety-based disorders including generalized anxiety disorder, specific phobias obsessive-compulsive disorder, panic disorder, and post-traumatic stress disorder“. The research is completed by using descriptive qualitative method in which the finding is presented in the form of description. The data of this study is obtained from the novel Family Ties by Danielle Steel.  The analysis finds that the dominant causes of the protagonist’s worry come from her nephews’ life which affects her life negatively. The effects of her worry will be a lesson for human life because every human being certainly has worry feeling in their life in certain situations.

Sign in / Sign up

Export Citation Format

Share Document