Could multiparametric magnetic resonance improve the detection rate of briganti nomogram in correctly identify prostate cancer patients without lymph node invasion?

Objectives: To determine if standard biopsy still has a role in the detection of prostate cancer or clinically significant prostate cancer in biopsy-naive patients with positive multiparametric magnetic resonance imaging. Materials and methods: We extracted, from our prospective maintained fusion biopsy database, patients from March 2014 to December 2018. The detection rate of prostate cancer and clinically significant prostate cancer and complication rate were analysed in a cohort of patients who underwent fusion biopsy alone (group A) or fusion biopsy plus standard biopsy (group B). The International Society of Urological Pathology grade group determined on prostate biopsy with the grade group determined on final pathology among patients who underwent radical prostatectomy were compared. Results: Prostate cancer was found in 249/389 (64.01%) and 215/337 (63.8%) patients in groups A and B, respectively ( P=0.98), while the clinically significant prostate cancer detection rate was 57.8% and 55.1% ( P=0.52). No significant differences in complications were found. No differences in the upgrading rate between biopsy and final pathology finding after radical prostatectomy were recorded. Conclusions: In biopsy-naive patients, with suspected prostate cancer and positive multiparametric magnetic resonance imaging the addition of standard biopsy to fusion biopsy did not increase significantly the detection rate of prostate cancer or clinically significant prostate cancer. Moreover, the rate of upgrading of the cancer grade group between biopsy and final pathology was not affected by the addition of standard biopsy. Level of evidence: Not applicable for this multicentre audit.

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PELVIC LYMPH NODE DISSECTION SHOULD BE OMITTED IN LOW RISK PROSTATE CANCER PATIENTS. RESULTS OF A MATCHED ANALYSIS

The Journal of Urology ◽

10.1016/s0022-5347(09)62109-1 ◽

2009 ◽

Vol 181 (4S) ◽

pp. 756-757

Author(s):

Alberto Briganti ◽

Alexander Haese ◽

Umberto Capitanio ◽

Andrea Gallina ◽

Felix K h Chun ◽

...

Keyword(s):

Prostate Cancer ◽

Lymph Node ◽

Cancer Patients ◽

Lymph Node Dissection ◽

Pelvic Lymph Node Dissection ◽

Low Risk ◽

Pelvic Lymph Node ◽

Node Dissection ◽

Risk Prostate Cancer ◽

Low Risk Prostate Cancer

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Relationship between prostate-specific antigen kinetics and detection rate of radiolabelled choline PET/CT in restaging prostate cancer patients: a meta-analysis

Clinical Chemistry and Laboratory Medicine (CCLM) ◽

10.1515/cclm-2013-0675 ◽

2014 ◽

Vol 52 (5) ◽

Cited By ~ 64

Author(s):

Giorgio Treglia ◽

Luca Ceriani ◽

Ramin Sadeghi ◽

Giampiero Giovacchini ◽

Luca Giovanella

Keyword(s):

Prostate Cancer ◽

Cancer Patients ◽

Prostate Specific Antigen ◽

Detection Rate ◽

Meta Analysis ◽

Specific Antigen ◽

Choline Pet ◽

Pet Ct

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Multi-Parameter Magnetic Resonance Imaging Fusion Technology Assists in Bone Diagnosis and Rehabilitation of Prostate Cancer

Journal of Medical Imaging and Health Informatics ◽

10.1166/jmihi.2021.3700 ◽

2021 ◽

Vol 11 (6) ◽

pp. 1753-1760

Author(s):

Yuzhu Jia ◽

Yibo Ying ◽

Jianju Feng

Keyword(s):

Magnetic Resonance Imaging ◽

Prostate Cancer ◽

Magnetic Resonance ◽

Early Diagnosis ◽

Detection Rate ◽

Diagnostic Technique ◽

Diagnostic Value ◽

Resonance Imaging ◽

High Risk Factors ◽

Transrectal Biopsy

Multi-parameter magnetic resonance imaging has been widely used in the diagnosis and evaluation of prostate cancer, and has important guiding significance for clinical diagnosis of prostate cancer and their treatment. This article studies the value of transrectal multiparametric ultrasound (mpUSS) in the diagnosis of clinically meaningful prostate cancer. 102 patients with high risk factors for prostate cancer were examined by mpUSS and mpMRI. The transrectal biopsy (SB) results of the prostate system were regarded as the excellent standard, and the diagnostic value of mpUSS, mpMRl and mpUSS combined with mpMRl examination for clinically meaningful prostate cancer was analyzed. The results showed that 58 of the 102 patients with SB were diagnosed with prostate cancer. Among them, 43 cases were detected by mpUSS, 50 cases were detected by mpMRl, 42 cases were detected by mpUSS combined with mpMRI (series), and 56 cases were detected by mpUSS combined with mpMRl (parallel). Grouped by Gleason score, the detection rate of mpUSS for clinically significant prostate cancer was 83.74%, and the detection rate of mpMRl was 93.5%. The comparison between the two was not statistically significant (P > 0.05), but when the two inspection methods were combined. The detection rate was 97.8%, which was significantly higher than the two inspection methods alone. Therefore, we conclude that mpUSS can be used as an imaging test for the diagnosis of prostate cancer. In addition, mpUSS has a high application value in the diagnosis of prostate cancer. The detection rate of mpUSS combined with mpMRl examination for clinically meaningful prostate cancer is significantly higher than that of mpMRl examination alone, which can be used as a diagnostic technique for early diagnosis of meaningful prostate cancer and can be used as a guide clinicians’ early diagnosis and treatment of meaningful prostate cancer.

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