scholarly journals A six-year study of coxsackievirus B infections in heart disease

1974 ◽  
Vol 73 (2) ◽  
pp. 165-172 ◽  
Author(s):  
N. R. Grist ◽  
Eleanor J. Bell
Keyword(s):  
Heart Disease ◽  
Cardiac Disease ◽  
Complement Fixation ◽  
Acute Myocarditis ◽  
Virus Infections ◽  
Coxsackievirus B ◽  
B Virus ◽  
Bacterial Pericarditis ◽  
Group B ◽  
Coxsackie Group

SUMMARYVirological examination of 385 patients with suspected heart disease and 26 with Bornholmdisease over a period of 6 years suggested that Coxsackie group B virus infections were associated with at least half the cases of acute myocarditis and one third of the cases ofacute non-bacterial pericarditis. Complement-fixation tests revealed only a few cardiac illnesses associated with other infections (influenza and Mycoplasma pneumoniae). No evidence of infection was found in chronic cardiac disease.

The role of Coxsackie Group B virus infections in sporadic myopericarditis

1971 ◽  
Vol 82 (6) ◽  
pp. 750-758 ◽  
Author(s):  
Clyde H. Koontz ◽  
C.George Ray
Keyword(s):  
Virus Infections ◽  
B Virus ◽  
Group B ◽  
Coxsackie Group

The Epidemiology of Enteroviruses

1975 ◽  
Vol 20 (1) ◽  
pp. 27-31 ◽  
Author(s):  
N. R. Grist ◽  
Eleanor J. Bell ◽  
D. Reid
Keyword(s):  
Cardiac Disease ◽  
Age Groups ◽  
Clinical Manifestations ◽  
Coxsackie Virus ◽  
Enterovirus Infection ◽  
Virus Infections ◽  
Mucous Membranes ◽  
Group A ◽  
Group B ◽  
Coxsackie Group

International and local Scottish data illustrate the epidemiology of enteroviruses in recent years. Polioviruses still predominate as causes of serious paralytic disease, except where controlled by vaccination and require continuing surveillance. Aseptic meningitis is the commonest reported illness due to enterovirus infection, but notable clinical manifestations of certain types (particularly coxsackie group A) involve the skin and mucous membranes and the respiratory tract. Gastrointestinal disturbance has been reported in some echovirus infections, and cardiac disease is particularly associated with group B coxsackie virus infections. Although most enterovirus infections are silent or trivial in severity, the trend towards periodic epidemicity of different enteroviruses involving older age-groups may entail the emergence of new disease problems of which heart disease may be one example.

Experimental Coxsackie group B virus infections

1963 ◽  
Vol 13 (1-3) ◽  
pp. 160-166 ◽  
Author(s):  
E. Irene Grodums ◽  
G. Dempster ◽  
W. A. Spencer
Keyword(s):  
Virus Infections ◽  
B Virus ◽  
Group B ◽  
Coxsackie Group

EXPERIMENTAL COXSACKIE B-3 INFECTION IN THE HIBERNATING SQUIRREL AND BAT

1961 ◽  
Vol 7 (4) ◽  
pp. 587-594 ◽  
Author(s):  
George Dempster ◽  
E. Irene Grodums ◽  
W. A. Spencer
Keyword(s):  
Ground Squirrel ◽  
Adult Mouse ◽  
Brown Fat ◽  
Young Mouse ◽  
B Virus ◽  
Group B ◽  
First Time ◽  
The Brain ◽  
Coxsackie B ◽  
Coxsackie Group

It has been shown for the first time that Coxsackie B-3 virus will infect hibernating mammals such as the ground squirrel and the bat, in both the hibernating and nonhibernating states. Pathological changes in the heart and brown fat of squirrels in hibernation were comparable with those observed in mice. In squirrels the brain appeared to be relatively resistant, although the region of the olfactory bulb was often involved. Although no lesions were observed in bats killed in hibernation, a few died with meningoencephalitis. Viraemia was observed in both species and found to be more persistent in the bat.Biochemical studies were conducted upon the normal brown fat of the different species, and it was interesting to find that whereas the morphology and lipid content (total lipid and phospholipid) of the young mouse, adult squirrel, and adult bat were very similar, the corresponding characters of adult mouse brown fat showed marked differences. The significance of the resemblance of young mouse brown fat to that found in the hibernating mammal is being assessed further in the light of the function of the brown fat and its susceptibility to Coxsackie group B virus infection.

Coxsackie Group B virus and primary myocardial disease in infants and children

1974 ◽  
Vol 88 (3) ◽  
pp. 311-314 ◽  
Author(s):  
Prapit Sudhas Na Ayuthya ◽  
Jidbhong Jayavasu ◽  
Boonchob Pongpanich
Keyword(s):  
Infants And Children ◽  
Myocardial Disease ◽  
B Virus ◽  
Group B ◽  
In Infants And Children ◽  
Coxsackie Group
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